Charge assignments in multiple-U(1) gauge theories

We discuss the choice of gauge field basis in multiple-U(1) gauge theories. We find that there is a preferred basis, specified by the charge orthogonality condition, in which the U(1) gauge fields do not mix under one-loop renormalization group running.Comment: 7 pages, LaTe

Electric circuit networks equivalent to chaotic quantum billiards

We formulate two types of electric RLC resonance network equivalent to quantum billiards. In the network of inductors grounded by capacitors squared resonant frequencies are eigenvalues of the quantum billiard. In the network of capacitors grounded by inductors squared resonant frequencies are given by inverse eigen values of the billiard. In both cases local voltages play role of the wave function of the quantum billiard. However as different from quantum billiards there is a heat power because of resistance of the inductors. In the equivalent chaotic billiards we derive the distribution of the heat power which well describes numerical statistics.Comment: 9 pages, 7 figure

The e!ects of a non-intervention HACCP implementation on process hygiene indicators on bovine and porcine carcasses

Four sites on each of 720 dressed carcasses (360 bovine and 360 porcine) were sampled (2,880 samples in total) in a single commercial abattoir slaughtering cattle and pigs using two separate slaughterlines. The carcasses were sampled before HACCP (pre-HACCP; 960 samples) and after HACCP implementation (post-HACCP; 1,920 samples) and Total Viable Count (TVC), Enterobacteriaceae count (EC) and Salmonella spp. prevalence were determined. During the pre-HACCP period, mean TVC levels on four tested sites varied on bovine carcasses between 3.03 and 4.19 log10 cfu/cm2 and on porcine carcasses between 3.73 and 3.99 log10 cfu/cm2. During the post-HACCP period, TVC levels on all tested sites on carcasses were further signicantly reduced, by 0.33-1.64 log and 1.13-2.04 log on bovine and porcine carcasses, respectively, compared to the pre-HACCP period. Both the EC occurrence in samples and EC levels in EC-positive samples somewhat decreased during post-HACCP as compared to pre-HACCP period, but the reductions were not statistically signicant due to large proportion of EC-negative samples and very low counts in EC-positive samples. Salmonella spp. was not detected in any of bovine or porcine carcass samples, regardless of whether they were taken pre- or post-HACCP. Overall, the processhygiene- improving eects of non-intervention HACCP have been proven through reduction of TVC on carcasses, but could not be veried in the present study through similar reductions in EC and/or Salmonella, because of their low levels and/or absence

Which Publications’ Metadata Are in Which Bibliographic Databases? A System for Exploration

The choice of databases containing publications’ metadata (i.e., bibliographic databases) determines the available publication list of any author and, thus, their public appearance and evaluation. Having all publications listed in the various bibliographic databases is therefore important for researchers. However, the average number of publications a researcher publishes per year is steadily rising, making it labor-intensive and time-consuming for authors to investigate whether all their publications are given in all bibliographic databases online. In this paper, we present RefBee, an online system that retrieves the metadata of all publications for a given author from the various bibliographic databases and indicates which publications are missing in which database. Our system is available online at http://refbee.org/ and supports Wikidata, ORCID, Google Scholar, VIAF, DBLP, Dimensions, Microsoft Academic, Semantic Scholar, and DNB/GNB. Our system not only can serve as assistance tool for more than 4.7 million researchers of any discipline and publication’s language, but also incentivizes the usage and population of Wikidata in the scholarly field

Investigating the value of radiomics stemming from DSC quantitative biomarkers in IDH mutation prediction in gliomas

Objective: This study aims to assess the value of biomarker based radiomics to predict IDH mutation in gliomas. The patient cohort consists of 160 patients histopathologicaly proven of primary glioma (WHO grades 2–4) from 3 different centers. Methods: To quantify the DSC perfusion signal two different mathematical modeling methods were used (Gamma fitting, leakage correction algorithms) considering the assumptions about the compartments contributing in the blood flow between the extra- and intra vascular space. Results: The Mean slope of increase (MSI) and the K1 parameter of the bidirectional exchange model exhibited the highest performance with (ACC 74.3% AUROC 74.2%) and (ACC 75% AUROC 70.5%) respectively. Conclusion: The proposed framework on DSC-MRI radiogenomics in gliomas has the potential of becoming a reliable diagnostic support tool exploiting the mathematical modeling of the DSC signal to characterize IDH mutation status through a more reproducible and standardized signal analysis scheme for facilitating clinical translation

Molecular approaches to identify and differentiate Bacillus anthracis from phenotypically similar Bacillus species isolates

BACKGROUND: Bacillus anthracis and Bacillus cereus can usually be distinguished by standard microbiological methods (e.g., motility, hemolysis, penicillin susceptibility and susceptibility to gamma phage) and PCR. However, we have identified 23 Bacillus spp. isolates that gave discrepant results when assayed by standard microbiological methods and PCR. We used multiple-locus variable-number tandem repeat analysis (MLVA), multiple-locus sequence typing (MLST), and phenotypic analysis to characterize these isolates, determine if they cluster phylogenetically and establish whether standard microbiological identification or PCR were associated with false positive/negative results. RESULTS: Six isolates were LRN real-time PCR-positive but resistant to gamma phage; MLVA data supported the identification of these isolates as gamma phage-resistant B. anthracis. Seventeen isolates were LRN real-time PCR-negative but susceptible to gamma phage lysis; these isolates appear to be a group of unusual gamma phage-susceptible B. cereus isolates that are closely related to each other and to B. anthracis. All six B. anthracis MLVA chromosomal loci were amplified from one unusual gamma phage-susceptible, motile, B. cereus isolate (although the amplicons were atypical sizes), and when analyzed phylogenetically, clustered with B. anthracis by MLST. CONCLUSION: MLVA and MLST aided in the identification of these isolates when standard microbiological methods and PCR could not definitely identify or rule out B. anthracis. This study emphasized the need to perform multiple tests when attempting to identify B. anthracis since relying on a single assay remains problematic due to the diverse nature of bacteria

alpha-Amylase Production in Fed BatchCultivation of Bacillus caldolyticus: An Interpretation of FermentationCourseUsing 2-D Gel Electrophoresis

The conditions for increased production of thermostable a-amylase from Bacillus caldolyticus DSM 405 were investigated. Preliminary experiments in batch shake flasks led to an optimized initial cultivation medium. Shake flask experiments in extended-batch and in fed-batch mode of operation indicated that the a-amylase production was enhanced by continuous feeding of starch. The activity of the a-amylase with optimized initial medium in batch-operated shake flasks was 5.7 U mL–1 compared to 15.4U mL–1 in the extended-batch culture and 21 U mL–1 in fed-batch culture. The improvements were achieved by avoiding any excess of starch in medium that led to accumulation of glucose followed by acetate formation. Adding casitone as the second component of the feeding solution in an aerated and agitated fed-batch bioreactor (3-liter working volume) led to an increased -amylase activity of up to 163.7 U mL.–1 All phases of cultivation were analyzed using 2D-gel electrophoresis in combination with nano LC-ESI-MS/MS for identification of altered proteins. Pyruvate kinase, 6-phosphofructokinase, GltC, anti-sigma F factor, glycogen synthase and several important variable proteins were detected. With help of these results, potential improvements of a two-component feeding strategy are discussed