64 research outputs found
Pattern formation on the surface of cationic-anionic cylindrical aggregates
Charged pattern formation on the surfaces of self--assembled cylindrical
micelles formed from oppositely charged heterogeneous molecules such as
cationic and anionic peptide amphiphiles is investigated. The net
incompatibility among different components results in the formation of
segregated domains, whose growth is inhibited by electrostatics. The transition
to striped phases proceeds through an intermediate structure governed by
fluctuations, followed by states with various lamellar orientations, which
depend on cylinder radius and . We analyze the specific heat,
susceptibility , domain size and morphology as a
function of and .Comment: Sent to PRL 11Jan05 Transferred from PRL to PRE 10Jun0
Peptide nanofiber scaffolds for multipotent stromal cell culturing
Self-assembled peptide nanofibers are versatile materials providing suitable platforms for regenerative medicine applications. This chapter describes the use of peptide nanofibers as extracellular matrix mimetic scaffolds for two-dimensional (2D) and three-dimensional (3D) multipotent stromal cell culture systems and procedures for in vitro experiments using these scaffolds. Preparation of 2D and 3D peptide nanofiber scaffolds and cell culturing procedures are presented as part of in vitro experiments including cell adhesion, viability, and spreading analysis. Analysis of cellular differentiation on peptide nanofiber scaffolds is described through immunocytochemistry, qRT-PCR, and other biochemical experiments towards osteogenic and chondrogenic lineage. © Springer Science+Business Media New York 2013
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