The Impact of I.T. on the Degree of Outsourcing, the Number of Suppliers, and the Duration of Contracts

It has long been accepted within theinformation technology (IT) researchcommunity that IT should have a profoundimpact on industrial organization. However,there has been as yet on the changes to be expected in the design of firms or industries; rather, there is an apparently inconsistent collection of conjectures and analyses. We are now able to offer an integrative framework for describing the impacts of IT on an industrial organization. Our analyses generally support the "move to the middle" hypothesis that states that the impact of IT on the organization of economic activity is to lead to a greater degree of outsourcing where this increased outsourcing is done from fewer suppliers with whom the buyer has long-term relationships.

Controversies in the management of early endometrial carcinoma: an update

Endometrial carcinoma (EC) is the commonest genital tract malignancy in developing countries and is usually confined to the uterus at the time of diagnosis with excellent prognosis and high cure rates. But the management is associated with lot of controversies like in staging, best surgical approach, extent of lymphadenectomy, adjuvant therapy, fertility sparing surgery in young women etc. A thorough surgical staging is important to determine uterine and extrauterine spread and also understanding of the pathophysiology and management strategies to identify women who are at high risk and tailoring the adjuvant treatment if necessary without increasing the morbidity. This evidence based narrative review conducted by searching Medline (1994- 2015) and other online articles from Pubmed, Google scholar. Articles were selected based on their currency and relevance to the discussion they summarize the current literature to provide an approach to best practice management of early endometrial carcinoma

Evidence for CO2-rich fluids in rocks from the type charnockite area near Pallavaram, Tamil Nadu

Fluid inclusion and mineral chemistry data was presented for samples from the type charnockite area near Pallavaram (Tamil Nadu, India). The results indicate the presence of a dense CO2 fluid phase, but the data cannot distinguish between influx of this fluid from elsewhere or localized migration of CO2-rich fluids associated with dehydration melting

Studies on the effect of moisture regimes on intercropping

Intercropping, a traditional cropping systems is being preferred widely by farmers of the developing tropics (Specially in subsistence farming of Africa and Asia)..

Mutagenicity assessment of Salacia chinensis by bacterial reverse mutation assay using histidine dependent Salmonella typhimurium tester strains

BACKGROUND AND OBJECTIVE: Genotoxicity analysis is one of the most important non-clinical environmental safety investigations required for pharmaceutical and agrochemical product registration. Any medicinal product must undergo a risk evaluation to determine its mutagenicity and carcinogenicity. MATERIALS AND METHODS: The Ames test is a commonly used in vitro test for determining a test chemical\u27s mutagenic activity. Histidine-dependent Salmonella typhimurium strains with a defective gene that causes the bacteria to synthesis the necessary amino acid histidine for life were tested for mutagenic potential. In order to reveal pro-mutagens and mutagens, the mutagenic potential of both plate integration and pre-incubation techniques was examined in the presence and absence of metabolizing system. Salacia chinensis has been widely used in ayurveda to treat various ailments. However, the information of mutagenicity of Salacia chinensis is scarce as per available literature. RESULTS: The mutagenicity of a Salacia chinensis root extract was investigated utilizing the Ames assay with plate incorporation and pre-incubation protocols using the appropriate Salmonella typhimurium tester strains: TA98, TA100, TA1537, TA1535, and TA102 in the presence and absence of S9. The concentrations used were 0.3123, 0.625, 1.25, 2.5 and 5 mg/plate. The extract of Salacia chinensis root did not show any mutagenic effect in any of the Salmonella typhimurium strains at the concentrations tested in the absence or presence of metabolic activation. CONCLUSION: The root of Salacia chinensis was hence confirmed to be non-mutagenic and at least according to the results of this genotoxicity evaluation can be regarded as being safe for human use

Splenic artery aneurysm: a case report with review of literature

Splenic Artery Aneurysm (SAA) is very rare in occurrence and they occur in approximately 1% of the population and are usually an incidental finding,but the necropsy studies have given rates as high as 10%. For its rarity in occurrence  here we present a case of splenic artery aneurysm in a 40 year old alcoholic presenting with upper and lower gastrointestinal bleeding. He was diagnosed as splenic artery aneurysm on CT scan and confirmed by laparotomy and pathological examination

Combined effect of bromelain and turmeric against acetic acid induced ulcerative colitis in wistar rats

Objective: The present study planned to study the combined effect of Bromelain and Turmeric in acetic acid induced ulcerative colitis in Wistar rats. Methodology: Wistar rats of either sex (n = 30) were divided into 5 groups. Group – I, Sham control, administered single dose of vehicle rectally; Group –II, colitis control, colitis was induced by rectal administration of single dose of 2 ml of 3%, v/v of acetic acid in 0.9% saline; Group–III, treated with Turmeric (50 mg/kg/p.o); Group–IV, treated with Bromelain (100 mg/kg/p.o) and Group –V, treated with both Turmeric (50 mg/kg/p.o) and Bromelain (100 mg /kg/p.o). Colitis was induced in all the treatment groups on first day and drug treatment was continued for 7 days. During the treatment period, Disease Activity Index (DAI) was assessed daily and on 8th day White Blood Cell (WBC) Count and Differential Leucocyte Count (DLC) was performed and on 9th day all the rats were sacrificed for the assessment of intestinal inflammation, colon myeloperoxidase (MPO) levels and Histopathology. Results obtained were analysed by one-way analysis of variance followed by Tukey’s multiple comparison test. Results: Overall changes in DAI, Inflammatory scores, WBC, DLC and MPO has shown significant improvement with Turmeric and Bromelain compared to Colitis control. However, the combined therapy has shown to be more effective in alleviating ulcerative colitis compared to individual therapies. Conclusion: The present study recommends that the combination of Turmeric and Bromelain has synergistic effect in treating ulcerative colitis

Evaluation of genetically mutated Trichoderma spp. for the management of Macrophomina phaseolina, incitant of charcoal rot of Sunflower

ABSTRACT A glasshouse experiment was conducted to evaluate the efficacy of genetically mutated Trichoderma spp. for the management of Macrophomina phaseolina, charcoal rot of sunflower. Out of 10 treatment combinations, maximum disease reduction was achieved by a combination of seed treatment + soil application of mutated strain TM 17 as this treatment recorded zero percent disease incidence. The same treatment also recorded maximum plant height (43.62 cm), shoot length (40.00 cm), root length (3.62 cm), maximum fresh weight of shoot (11.90 gm), root (3.40 gm) and maximum dry weight of shoot (0.98 g) and root (0.56 gm) of sunflower when compared to other treatments