The Resummed Photon Spectrum in Radiative Upsilon Decays

We present a theoretical prediction for the photon spectrum in radiative Upsilon decay including the effects of resumming the endpoint region, E_\gamma -> M_\Upsilon/2. Our approach is based on NRQCD and the soft collinear effective theory. We find that our results give much better agreement with data than the leading order NRQCD prediction.Comment: 4 pages, 6 figure

Flavor-singlet light-cone amplitudes and radiative Upsilon decays in SCET

We study the evolution of flavor-singlet, light-cone amplitudes in the soft-collinear effective theory (SCET), and reproduce results previously obtained by a different approach. We apply our calculation to the color-singlet contribution to the photon endpoint in radiative Upsilon decay. In a previous paper, we studied the color-singlet contributions to the endpoint, but neglected operator mixing, arguing that it should be a numerically small effect. Nevertheless the mixing needs to be included in a consistent calculation, and we do just that in this work. We find that the effects of mixing are indeed numerically small. This result combined with previous work on the color-octet contribution and the photon fragmentation contribution provides a consistent theoretical treatment of the photon spectrum in radiative Upsilon decay.Comment: 19 pages with 8 figure

Brain structure in pediatric Tourette syndrome

Previous studies of brain structure in Tourette syndrome (TS) have produced mixed results, and most had modest sample sizes. In the present multicenter study, we used structural magnetic resonance imaging (MRI) to compare 103 children and adolescents with TS to a well-matched group of 103 children without tics. We applied voxel-based morphometry methods to test gray matter (GM) and white matter (WM) volume differences between diagnostic groups, accounting for MRI scanner and sequence, age, sex and total GM+WM volume. The TS group demonstrated lower WM volume bilaterally in orbital and medial prefrontal cortex, and greater GM volume in posterior thalamus, hypothalamus and midbrain. These results demonstrate evidence for abnormal brain structure in children and youth with TS, consistent with and extending previous findings, and they point to new target regions and avenues of study in TS. For example, as orbital cortex is reciprocally connected with hypothalamus, structural abnormalities in these regions may relate to abnormal decision making, reinforcement learning or somatic processing in TS

Dopamine buffering capacity imaging: A pharmacodynamic fMRI method for staging Parkinson disease

We propose a novel pharmacological fMRI (phMRI) method for objectively quantifying disease severity in Parkinson disease (PD). It is based on the clinical observation that the benefit from a dose of levodopa wears off more quickly as PD progresses. Biologically this has been thought to represent decreased buffering capacity for dopamine as nigrostriatal cells die. Buffering capacity has been modeled based on clinical effects, but clinical measurements are influenced by confounding factors. The new method proposes to measure the effect objectively based on the timing of the known response of several brain regions to exogenous levodopa. Such responses are robust and can be quantified using perfusion MRI. Here we present simulation studies based on published clinical dose-response data and an intravenous levodopa infusion. Standard pharmacokinetic-pharmacodynamic methods were used to model the response. Then the effect site rate constan

TicTimer Web: Software for measuring tic suppression remotely

Woods and Himle developed a standardized tic suppression paradigm (TSP) for the experimental setting, to quantify the effects of intentional tic suppression in Tourette syndrome. We previously provided a computer program to facilitate recording tic occurrence and to automate reward delivery during the several experimental conditions of the TSP. The present article describes a web-based program that performs the same functions. Implementing this program on the web allows research sessions to be performed remotely, in tandem with a video calling program. Relevant data for each session, such as the timing of tics and dispensed rewards, are stored in plain text files for later analysis. Expected applications include research on Tourette syndrome and related disorders

Variational Cluster Perturbation Theory for Bose-Hubbard models

We discuss the application of the variational cluster perturbation theory (VCPT) to the Mott-insulator--to--superfluid transition in the Bose-Hubbard model. We show how the VCPT can be formulated in such a way that it gives a translation invariant excitation spectrum -- free of spurious gaps -- despite the fact that if formally breaks translation invariance. The phase diagram and the single-particle Green function in the insulating phase are obtained for one-dimensional systems. When the chemical potential of the cluster is taken as a variational parameter, the VCPT reproduces the dimension dependence of the phase diagram even for one-site clusters. We find a good quantitative agreement with the results of the density-matrix renormalization group when the number of sites in the cluster becomes of order 10. The extension of the method to the superfluid phase is discussed.Comment: v1) 10 pages, 6 figures. v2) Final version as publishe