What is Intellectual Freedom Today? An Invitation to Think the Event

The pubmed search term “pastoris[Title] AND (express[Title] OR produced[Title] OR expression[Title] OR production[Title])” yielded 877 hits in December 2008, dated from 1987 to 2009. At the same time, the search term “pastoris[Title] AND (bioreactor[Title] OR fed-batch[Title] OR continuous[Title] OR fermentations[Title] OR large-scale[Title] OR fermentation[Title] OR pilot[Title])” returned 92 hits –published between 1990 and 2009. This analysis is somewhat superficial and ostentatious, but it suggests that the majority of researchers publishing on Pichia use it as a tool for rather than an object of their work. This is not to say that the majority should change their focus, but in fact researchers sometimes face difficulties when the need to obtain useful amounts of a target protein produced in Pichia calls for scale-up from the benchtop protocols to a bioreactor-based process. This chapter attempts to provide a reliable protocol for AOX1-driven bioreactor production of secreted scFvs or other proteins

Neue und verbesserte Verfahren der Blechumformung. Teilprojekt: Prozessueberwachung. Bereich Kraft- und Koerperschallueberwachung/Qualitaetssicherung Abschlussbericht

Available from TIB Hannover: F97B257 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman

Neue und verbesserte Verfahren des Warmumformens. Teilprojekt: Prozessueberwachung, Praezisionsschmieden

The objective of this subproject was to develop a process monitoring system for the project areas forging and precision forging. For the area of forging a completely new process monitoring system was developed, another system was modified and adapted to the conditions of hot working. Extensive work was also carried out in the field of precision forging. At the beginning of the project, the fundamentals for a process monitoring system were developed. During the concept phase, a practical process monitoring system for hot working was projected. During the realization phase, this system was implemented in terms of hardware and software. Eventually, during the test phase, two systems for process monitoring on hot working machines were developed to maturity for series production. One of the main tasks, the appropriate selection and arrangement of sensors, as close to the process as possible, was accomplished and is commercially available now. (orig.)SIGLEAvailable from TIB Hannover: F95B1159+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Forschung und Technologie (BMFT), Bonn (Germany)DEGerman