Cortical regions displaying thinning of the cortex and increased surface area in PSP.

<p>X;Y;Z in Talairach coordinates. All results presented at the corrected threshold (p <0.05).</p><p>MSA  =  Multiple Systems Atrophy; PSP  =  Progressive Supranuclear Palsy; PD  =  Parkinson's Disease.</p><p>Cortical regions displaying thinning of the cortex and increased surface area in PSP.</p

Cortical areas showing significant thinning in PSP patients compared to a) healthy controls, b) Parkinson's disease and c) Multiple System Atrophy; displayed on QDEC's semi-inflated cortical surfaces.

<p>Top row: L lateral and L medial, Second row: R lateral and R medial, Third row: anterior and posterior, Bottom row: superior and inferior views. The colour bar indicates the significance levels of the clusters. Results were obtained using Monte Carlo simulation, with a threshold of p <0.05, to provide cluster-wise correction for multiple comparisons.</p

Cortical areas showing significantly increased surface area in PSP patients compared to Multiple System Atrophy; displayed on QDEC's semi-inflated cortical surfaces.

<p>Top row: L lateral and L medial, Second row: R lateral and R medial, Third row: anterior and posterior, Bottom row: superior and inferior views. The colour bar indicates the significance levels of the clusters. Results were obtained using Monte Carlo simulation, with a threshold of p <0.05, to provide cluster-wise correction for multiple comparisons.</p