78 research outputs found

    An approximate dynamic programming approach to food security of communities following hazards

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    Food security can be threatened by extreme natural hazard events for households of all social classes within a community. To address food security issues following a natural disaster, the recovery of several elements of the built environment within a community, including its building portfolio, must be considered. Building portfolio restoration is one of the most challenging elements of recovery owing to the complexity and dimensionality of the problem. This study introduces a stochastic scheduling algorithm for the identification of optimal building portfolio recovery strategies. The proposed approach provides a computationally tractable formulation to manage multi-state, large-scale infrastructure systems. A testbed community modeled after Gilroy, California, is used to illustrate how the proposed approach can be implemented efficiently and accurately to find the near-optimal decisions related to building recovery following a severe earthquake.Comment: As opposed to the preemptive scheduling problem, which was addressed in multiple works by us, we deal with a non-preemptive stochastic scheduling problem in this work. Submitted to 13th International Conference on Applications of Statistics and Probability in Civil Engineering, ICASP13 Seoul, South Korea, May 26-30, 201

    Solving Markov decision processes for network-level post-hazard recovery via simulation optimization and rollout

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    Computation of optimal recovery decisions for community resilience assurance post-hazard is a combinatorial decision-making problem under uncertainty. It involves solving a large-scale optimization problem, which is significantly aggravated by the introduction of uncertainty. In this paper, we draw upon established tools from multiple research communities to provide an effective solution to this challenging problem. We provide a stochastic model of damage to the water network (WN) within a testbed community following a severe earthquake and compute near-optimal recovery actions for restoration of the water network. We formulate this stochastic decision-making problem as a Markov Decision Process (MDP), and solve it using a popular class of heuristic algorithms known as rollout. A simulation-based representation of MDPs is utilized in conjunction with rollout and the Optimal Computing Budget Allocation (OCBA) algorithm to address the resulting stochastic simulation optimization problem. Our method employs non-myopic planning with efficient use of simulation budget. We show, through simulation results, that rollout fused with OCBA performs competitively with respect to rollout with total equal allocation (TEA) at a meagre simulation budget of 5-10% of rollout with TEA, which is a crucial step towards addressing large-scale community recovery problems following natural disasters.Comment: Submitted to Simulation Optimization for Cyber Physical Energy Systems (Special Session) in 14th IEEE International Conference on Automation Science and Engineerin

    Design and analysis of truck body for increasing the payload capacity

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    Truck industry is a major source of transportation in India. With an average truck travelling about 300 kilometers per day [1], every kilogram of truck weight is of concern to the industry in order to get the best out of the truck. The main objective of this project is to increase the payload capacity of automotive truck body. Every kilogram of increased vehicle weight will decrease the vehicle payload capacity in turn increasing the manufacturing cost and reducing the fuel economy by increase the fuel consumption. With the intension of weight reduction, standard truck body has been designed and analyzed in ANSYS software. C-cross section beams were used instead of conventional rectangular box sections to reduce the weight of the body. Light-weight Aluminum alloy Al 6061 T6 is used to increase the payload capacity. The strength of the Truck platform is monitored in terms of deformation and stress concentration

    Reliable identification of protein-protein interactions by crosslinking mass spectrometry

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    Protein-protein interactions govern most cellular pathways and processes, and multiple technologies have emerged to systematically map them. Assessing the error of interaction networks has been a challenge. Crosslinking mass spectrometry is currently widening its scope from structural analyses of purified multi-protein complexes towards systems-wide analyses of protein-protein interactions (PPIs). Using a carefully controlled large-scale analysis of Escherichia coli cell lysate, we demonstrate that false-discovery rates (FDR) for PPIs identified by crosslinking mass spectrometry can be reliably estimated. We present an interaction network comprising 590 PPIs at 1% decoy-based PPI-FDR. The structural information included in this network localises the binding site of the hitherto uncharacterised protein YacL to near the DNA exit tunnel on the RNA polymerase.TU Berlin, Open-Access-Mittel – 2021DFG, 390540038, EXC 2008: Unifying Systems in Catalysis "UniSysCat"DFG, 392923329, GRK 2473: Bioaktive Peptide - Innovative Aspekte zur Synthese und BiosyntheseDFG, 426290502, Erfassung der strukturellen Organisation des Mycoplasma pneumoniae Proteoms mittels in-Zell Crosslinking-Massenspektrometri
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