20 research outputs found

    Corticosteroids in ophthalmology : drug delivery innovations, pharmacology, clinical applications, and future perspectives

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    Magnetic resonance imaging investigations of position of conus medullaris in adolescent idiopathic scoliosis as a peripheral neuropathy

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    Adolescent idiopathic scoliosis (AIS) is a structural 3-dimensional deformity the spine, which is occurring between 10 years of age and skeletal maturity and it mostly affects prepuberbal girls. The etiology of AIS remains unknown and seems should be multifactorial. According to the theories, there could be a shorter spinal cord or a higher location of the conus medullaris and disproportionate growth in neuro-osseous system. This study wants to investigate the position of the conus medullaris in AIS patients with a large curve magnitude in comparison with healthy adolescents. 94 AIS patients consisting of 25 males and 69 females between 11 and 25 years old, based on physical examination and standing posteroanterior roentgenography of the total spine with a Cobb angle more than 40 degrees was chosen. The main curve magnitude of every AIS patient was measured by the Cobb method. Apex of deformity was determined based on SRS definition. Patients� deformity were calcified based on Lenke classification. Magnetic resonance imaging examinations of the total spine were performed in the AIS group, by means of a 1.5-T magnetic resonance imaging system. The position of conus medullaris was defined according to the method by saffiudin et al and was assessed based on the age, sex, type of deformity, severity of deformity, kyphosis, lordosis, flexibility, apical vertebra, stable vertebra. The mean age of patients were 16.34 with 6.77 of conus medullaris position in mean, which was lower one-third of L1. Our study showed no significant correlation between the position of conus medullaris with age, weight, preoperative curve, flexibility, types of deformity based on Lenke classification and degree of kyphosis and lordisis. In conclusion, there is the same mean and the distribution of the conus medullaris locations for AIS patients and normal populations. © 2015, E-Century Publishing Corporation. All rights reserved

    Multivariate analysis of 200-m front crawl swimming performance in young male swimmers

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    The aim of the present study was to evaluate the biomechanical (stroke rate, stroke length, and stroke index), anthropometrical (body height, body mass, body mass index, arm span, shoulders width, thigh, leg and upper arm lengths), and muscle architectural (muscle thickness, pennation angle, and fascicle length) parameters as predictors of 200-m front crawl swimming performance in young male swimmers. Twenty-two county level male swimmers (mean ±SD: age: 14.52 ± 0.77 years; body height: 173 ± 5 m; body mass: 60.5 ± 5.7 kg) performed a 200-m front crawl swimming test in a 25-m pool. Stepwise regression analysis revealed that biomechanical parameters (87%) characterized best 200-m front crawl swimming performance, followed by anthropometrical (82%) and muscle architectural (72%) parameters. Also, stroke length (R2 = 0.623), body height (R2 = 0.541), fascicle length of Triceps Brachii (R2 = 0.392) were the best single predictors that together explained 92% of the variability of the 200-m front crawl swimming performance in these swimmers. As a conclusion, with respect to higher performance prediction power of biomechanical parameters, technique should represent the core of the training program at these ages. In addition, these findings could be used for male young swimmers selection and talent identification
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