The geology and petrogenesis of the southern closepet granite

The Archaean Closepet Granite is a polyphase body intruding the Peninsular Gneiss Complex and the associated supracrustal rocks. The granite out-crop runs for nearly 500 km with an approximate width of 20 to 25 km and cut across the regional metamorphic structure passing from granulite facies in the South and green schist facies in the north. In the amphibolite-granulite facies transition zone the granite is intimately mixed with migmatites and charnockite. Field observations suggests that anatexis of Peninsular gneisses led to the formation of granite melt, and there is a space relationship between migmatite formation, charnockite development and production and emplacement of granite magma. Based on texture and cross cutting relationships four major granite phases are recognized: (1) Pyroxene bearing dark grey granite; (2) Porphyritec granite; (3) Equigranular grey granite; and (4) Equigranular pink granite. The granite is medium to coarse grained and exhibit hypidiomorphic granular to porphyritic texture. The modal composition varies from granite granodiorite to quartz monzonite. Geochemical variation of the granite suite is consistent with either fractional crystallization or partial melting, but in both the cases biotite plus feldspar must be involved as fractionating or residual phases during melting to account trace element chemistry. The trace element data has been plotted on discriminant diagrams, where majority of samples plot in volcanic arc and within plate, tectonic environments. The granite show distinct REE patterns with variable total REE content. The REE patterns and overall abundances suggests that the granite suite represents a product of partial melting of crustal source in which fractional crystallization operated in a limited number of cases

Rugged switch responds to minute pressure differentials

Pressure responsive switching device exhibits high sensitivity but is extremely rugged and resistant to large amplitude shock and velocity loading. This snap-action, single pole-double throw switch operates over a wide temperature range

Surface Acoustic Wave Driven Microchannel Flow

We demonstrate that the propagation of surface acoustic waves, arising from the excitation of the acoustic field on a piezoelectric crystal (lithium niobate) substrate, along the sidewalls of microchannels (50 μm or 280 μm wide and 200 μm deep) fabricated in the substrate, can give rise to throughflow with velocities of the order 10 mm/s. This streaming flow in the direction along which the surface acoustic wave propagates is a result of the leakage of acoustic radiation from the substrate walls into the fluid. Good agreement is obtained between these preliminary experimental results with those from numerical simulations of the classical acoustic streaming model. In any case, these results show the potential of surface acoustic wave micropumps to be an effective fluid-driving mechanism for microfluidic devices

Parallax and Distance Estimates for Fourteen Cataclysmic Variable Stars

I used the 2.4 m Hiltner telescope at MDM Observatory in an attempt to measure trigonometric parallaxes for 14 cataclysmic variable stars. Techniques are described in detail. In the best cases the parallax uncertainties are below 1 mas, and significant parallaxes are found for most of the program stars. A Bayesian method which combines the parallaxes together with proper motions and absolute magnitude constraints is developed and used to derive distance estimates and confidence intervals. The most precise distance derived here is for WZ Sge, for which I find 43.3 (+1.6, -1.5) pc. Six Luyten Half-Second stars with previous precise parallax measurements were re-measured to test the techniques, and good agreement is found.Comment: 33 pages, 3 figures. Astronomical Journal, accepte

Efficacies of liposome-encapsulated streptomycin and ciprofloxacin against Mycobacterium avium-M. intracellulare complex infections in human peripheral blood monocyte/macrophages

Current treatments of disseminated infection caused by the Mycobacterium avium-M. intracellulare complex (MAC) are generally ineffective. Liposome- mediated delivery of antibiotics to MAC-infected tissues in vivo can enhance the efficacy of the drugs (N. Duzgunes, V. K. Perumal, L. Kesavalu, J. A. Goldstein, R. J. Debs, and P. R. J. Gangadharam, Antimicrob. Agents Chemother. 32:1404-1411, 1988; N. Duzgunes, D. A. Ashtekar, D. L. Flasher, N. Ghori, R. J. Debs, D. S. Friend, and P. R. J. Gangadharam, J. Infect. Dis. 164:143-151, 1991). We investigated the therapeutic efficacies of liposome- encapsulated streptomycin and ciprofloxacin against growth of the MAC inside human peripheral blood monocyte/macrophages. Treatment was initiated 24 h after infection of macrophages with the MAC and stopped after 20 h, and the cells were incubated for another 7 days. The antimycobacterial activity of streptomycin was enhanced when the drug was delivered to macrophages in liposome-encapsulated form, reducing the CFU about threefold more than the free drug did throughout the concentration range studied (10 to 50 μg/ml). With 50 μg of encapsulated streptomycin per ml, the CFU were reduced to 11% of the initial level of infection. Liposome-encapsulated ciprofloxacin was at least 50 times more effective against the intracellular bacteria than was the free drug: at a concentration of 0.1 μg/ml, liposome-encapsulated ciprofloxacin had greater antimycobacterial activity than the free drug at 5 μg/ml. With liposome-encapsulated ciprofloxacin at 5 μg/ml, the CFU were reduced by more than 1,000-fold at the end of the 7-day incubation period, compared with untreated controls. These results suggest that liposome- encapsulated ciprofloxacin or other fluoroquinolones may be effective against MAC infections in vivo

Advanced information processing system: The Army fault tolerant architecture conceptual study. Volume 1: Army fault tolerant architecture overview

Digital computing systems needed for Army programs such as the Computer-Aided Low Altitude Helicopter Flight Program and the Armored Systems Modernization (ASM) vehicles may be characterized by high computational throughput and input/output bandwidth, hard real-time response, high reliability and availability, and maintainability, testability, and producibility requirements. In addition, such a system should be affordable to produce, procure, maintain, and upgrade. To address these needs, the Army Fault Tolerant Architecture (AFTA) is being designed and constructed under a three-year program comprised of a conceptual study, detailed design and fabrication, and demonstration and validation phases. Described here are the results of the conceptual study phase of the AFTA development. Given here is an introduction to the AFTA program, its objectives, and key elements of its technical approach. A format is designed for representing mission requirements in a manner suitable for first order AFTA sizing and analysis, followed by a discussion of the current state of mission requirements acquisition for the targeted Army missions. An overview is given of AFTA's architectural theory of operation

Advanced information processing system: The Army fault tolerant architecture conceptual study. Volume 2: Army fault tolerant architecture design and analysis

Described here is the Army Fault Tolerant Architecture (AFTA) hardware architecture and components and the operating system. The architectural and operational theory of the AFTA Fault Tolerant Data Bus is discussed. The test and maintenance strategy developed for use in fielded AFTA installations is presented. An approach to be used in reducing the probability of AFTA failure due to common mode faults is described. Analytical models for AFTA performance, reliability, availability, life cycle cost, weight, power, and volume are developed. An approach is presented for using VHSIC Hardware Description Language (VHDL) to describe and design AFTA's developmental hardware. A plan is described for verifying and validating key AFTA concepts during the Dem/Val phase. Analytical models and partial mission requirements are used to generate AFTA configurations for the TF/TA/NOE and Ground Vehicle missions

The Anatomy of EMTALA: A Litigator\u27s Guide.

The Emergency Medical Treatment and Active Labor Act (EMTALA) prohibits hospitals from inappropriately transferring or refusing medical care to persons with emergency medical conditions. EMTALA was passed in response to the practice of “dumping” seriously ill patients from private hospitals into public ones, to ensure all patients receive medical treatment in emergency situations. Plaintiffs have attempted to pursue EMTALA claims against non-hospital defendants, but courts have consistently disallowed such claims under the statute. By limiting the scope of its coverage to hospitals, EMTALA creates a situation unique from ordinary medical malpractice. Although hospitals may be held liable for negligent credentialing or supervision of physicians, hospitals are ordinarily not liable for physicians’ conduct or alleged medical malpractice. Under EMTALA, a hospital is liable for the emergency medicine physician’s conduct and decisions, because hospitals can only act by relying on the actions of its licensed physicians and hospital staff. EMTALA does not make physicians agents of the hospital for any purpose other than conduct specified by the statute and does not impute the physician’s tortious conduct regarding diagnosis and treatment to the hospital. Attorneys litigating EMTALA cases must have a clear understanding of the nature and application of every provision in the statute to provide proper representation. A hospital’s conduct must be evaluated based on the specific duty of care associated with each provision of the statute. In contrast, a determination of whether a hospital has breached the duty to stabilize a patient’s condition prior to transfer utilizes a more objective standard. This standard focuses on whether deterioration of the patient’s condition was likely to occur within reasonable medical probability. Though plaintiffs often seek to interject standards of liability based on negligence or medical malpractice, Congress did not intent for EMTALA to address injuries already redressed by state law

Non-Oberbeck-Boussinesq effects in turbulent thermal convection in ethane close to the critical point

As shown in earlier work (Ahlers et al., J. Fluid Mech. 569, p.409 (2006)), non-Oberbeck Boussinesq (NOB) corrections to the center temperature in turbulent Rayleigh-Benard convection in water and also in glycerol are governed by the temperature dependences of the kinematic viscosity and the thermal diffusion coefficient. If the working fluid is ethane close to the critical point the origin of non-Oberbeck-Boussinesq corrections is very different, as will be shown in the present paper. Namely, the main origin of NOB corrections then lies in the strong temperature dependence of the isobaric thermal expansion coefficient \beta(T). More precisely, it is the nonlinear T-dependence of the density \rho(T) in the buoyancy force which causes another type of NOB effect. We demonstrate that through a combination of experimental, numerical, and theoretical work, the latter in the framework of the extended Prandtl-Blasius boundary layer theory developed in Ahlers et al., J. Fluid Mech. 569, p.409 (2006). The latter comes to its limits, if the temperature dependence of the thermal expension coefficient \beta(T) is significant.Comment: 18 pages, 15 figures, 3 table