1,016 research outputs found

    Doing Interventions : Experiments and Collaborations in Contemporary Ethnography

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    In dieser Einleitung zur 83. Ausgabe der Kulturanthropologie Notizen stellen wir das Konzept der Intervention ins Zentrum und betonen wie Forscher:innen und ihre Felder immer aufeinander bezogen sind. Während wir grundsätzlich davon ausgehen, dass ethnographische Studien per se als interventionistisch verstanden werden können, diskutieren wir ‚doing interventions‘ als einen spezifischen, ethnographischen methodischen Ansatz und reflektieren insbesondere Experimente und Kollaborationen sowie deren epistemischen Effekte. In diesem Sinne verweisen Interventionen mit/in der Ethnographie auf ethnographisches Wissen, das einen Effekt auf das Feld hat, während die Praxis des Intervenierens zugleich auch die ethnographische Wissensproduktion verändern kann. Die Autor:innen dieser Ausgabe der Kulturanthropologie Notizen zeigen anhand einer Vielzahl von Beispielen, wie sich Interventionen mit und in der Ethnographie in der Praxis ausgestalten lassen und wie diese Modi miteinander verflochten sind. Die Fallstudien reichen von ethnografischer Forschung im globalen Lebensmittelsektor und in der Rohstoffindustrie über Feldforschung in und mit der Sozialpsychiatrie bis hin zu neuen Formen der Zusammenarbeit während der COVID-19-Pandemie. Nicht zuletzt wird die Anthropologie als Veränderungswissenschaft diskutiert. Was die Texte eint, ist die Überzeugung, dass Interventionen mit/in der Ethnographie das Potential haben Etabliertes und Selbstverständliches in Frage zu stellen, normative und dominante Wahrnehmungen der Wissensproduktion zu transformieren, Diskurse zu irritieren und gleichzeitig die Re-Imagination und Re-Konzeptualisierung der ethnographischen Praxis  zu fördern

    Comparing the Safety and Efficacy of a Rapid High-Sensitivity Cardiac Troponin I Protocol Between Hospital-Based and Free-Standing Emergency Departments

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    Study Objectives: Current high sensitivity cardiac troponin I (hs-cTnI) research has been conducted almost exclusively in hospital-based emergency department (HBED) settings and the translation of these protocols into free-standing emergency departments (FSED) has yet to be explored. This study compared the safety and efficacy of applying a rapid-rule out protocol using hs-cTnI for exclusion of acute myocardial infarction (AMI) in HBEDs and FSEDs. Methods: This was a secondary analysis of a randomized trial of patients evaluated for possible AMI in 9 emergency departments (ED) from July 2020 through March 2021. The trial arms included a new 0/1-hour rapid protocol using hs-cTnI versus standard care, which used a 0/3-hour protocol without reporting hs-cTnI values below the 99th percentile. The primary outcome was safe ED discharge, defined as discharge with no death or AMI within 30-days. Analysis included a mixed-effect model adjusting for demographic variables. Results: There was a statistically significant difference in safe discharges from FSEDs when comparing the standard care arm (86.2%) to the rapid rule-out protocol (95.1%). There was a statistically significant reduction in FSED length of stay with application of a rapid rule-out protocol at 3.43 hours vs. 3.97 hours using standard care. The percentage of patients who ruled-out with their initial hs-cTnI (\u3c4 ng/L) at FSEDs (74%) was also significantly larger when compared to HBEDs (54%). Conclusion: Implementation of a hs-cTnI rapid 0/1-hour protocol to evaluate for AMI in FSEDs is feasible and had greater impact on safe ED discharge and length of stay compared to HBEDs

    Translational Medicine - doing it backwards

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    In recent years the concept of "translational medicine" has been advanced in an attempt to catalyze the medical applications of basic biomedical research. However, there has been little discussion about the readiness of scientists themselves to respond to what we believe is a required new approach to scientific discovery if this new concept is to bear fruit. The present paradigm of hypothesis-driven research poorly suits the needs of biomedical research unless efforts are spent in identifying clinically relevant hypotheses. The dominant funding system favors hypotheses born from model systems and not humans, bypassing the Baconian principle of relevant observations and experimentation before hypotheses. Here, we argue that that this attitude has born two unfortunate results: lack of sufficient rigor in selecting hypotheses relevant to human disease and limitations of most clinical studies to certain outcome parameters rather than expanding knowledge of human pathophysiology; an illogical approach to translational medicine. If we wish to remain true to our responsibility and duty of performing research relevant to human disease, we must begin to think about fundamental new approaches

    A public health response to the methamphetamine epidemic: the implementation of contingency management to treat methamphetamine dependence

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    BACKGROUND: In response to increases in methamphatemine-associated sexually transmitted diseases, the San Francisco Department of Public Health implemented a contingency management (CM) field program called the Positive Reinforcement Opportunity Project (PROP). METHODS: Methamphetamine-using men who have sex with men (MSM) in San Francisco qualified for PROP following expressed interest in the program, provision of an observed urine sample that tested positive for methamphetamine metabolites and self-report of recent methamphetamine use. For 12 weeks, PROP participants provided observed urine samples on Mondays, Wednesdays and Fridays and received vouchers of increasing value for each consecutive sample that tested negative to metabolites of methamphetamine. Vouchers were exchanged for goods and services that promoted a healthy lifestyle. No cash was provided. Primary outcomes included acceptability (number of enrollments/time), impact (clinical response to treatment and cost-effectiveness as cost per patient treated). RESULTS: Enrollment in PROP was brisk indicating its acceptability. During the first 10 months of operation, 143 men sought treatment and of these 77.6% were HIV-infected. Of those screened, 111 began CM treatment and averaged 15 (42%) methamphetamine-free urine samples out of a possible 36 samples during the 12-week treatment period; 60% completed 4 weeks of treatment; 48% 8 weeks and 30% 12 weeks. Across all participants, an average of 159(SD=159 (SD = 165) in vouchers or 35.1% of the maximum possible (453)wasprovidedfortheseparticipants.Theaveragecostperparticipantofthe143treatedwas453) was provided for these participants. The average cost per participant of the 143 treated was 800. CONCLUSION: Clinical responses to CM in PROP were similar to CM delivered in drug treatment programs, supporting the adaptability and effectiveness of CM to non-traditional drug treatment settings. Costs were reasonable and less than or comparable to other methamphetamine outpatient treatment programs. Further expansion of programs like PROP could address the increasing need for acceptable, feasible and cost-effective methamphetamine treatment in this group with exceptionally high rates of HIV-infection
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