4,334 research outputs found

    Nomogram for the Evaluation of Blackbody Radiancy and of Peak and Total Intensities for Spectral Lines with Doppler Contour

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    A nomogram has been constructed for the determination of blackbody radiancy and of peak and total intensities for spectral lines with Doppler contour. The basic equations used for the construction of the nomogram and the use of the nomogram are described briefly. A method is outlined for determining absolute values of total intensities for spectral lines with combined Doppler and resonance contour by using the nomogram in conjunction with the “curves of growth.

    Through-flow solution for axial-flow turbomachine blade rows

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    Through flow solution for axial flow turbomachine blade row

    Angular distributions of γ rays from the 7Li(p,γ) reaction at low energies

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    Angular distributions of the 14–17 MeV γ rays from the 7Li(p,γ) reaction at Ep=450, 402, and 80 keV were measured at 0°≤θlab≤135°, using a BGO detector and a 28-μg/cm2 LiF target. The angular distributions at Ep=450 and 402 keV agree with the previous results by Mainsbridge; at Ep=80 keV the ground-state transition is anisotropic on the order of 20%, confirming recent results by Chasteler et al

    Universal Design for Learning (UDL) in the Academic Library: A Methodology for Mapping Multiple Means of Representation in Library Tutorials

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    Librarians designed a biology tutorial not only to address an assignment, but also to make tutorials more accessible to students with various learning styles. The Science Librarian created the content by using aspects of the Information Literacy Standards for Science and Technology/Engineering, an informal survey of biology faculty, and assignments for the biology labs. The Instructional Design Librarian created multiple modules that engaged users through text, images, audio, and interactive tutorials. The researchers used Universal Design for Learning principles to address multiple learning styles, specifically multiple means of representation and created a mapping technique for those principles that can be applied to any library tutorial. To assess the effectiveness, students with learning disabilities completed a usability test on the tutorial

    Aerodynamics of advanced axial-flow turbomachinery

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    A multi-task research program on aerodynamic problems in advanced axial-flow turbomachine configurations was carried out at Iowa State University. The elements of this program were intended to contribute directly to the improvement of compressor, fan, and turbine design methods. Experimental efforts in intra-passage flow pattern measurements, unsteady blade row interaction, and control of secondary flow are included, along with computational work on inviscid-viscous interaction blade passage flow techniques. This final report summarizes the results of this program and indicates directions which might be taken in following up these results in future work. In a separate task a study was made of existing turbomachinery research programs and facilities in universities located in the United States. Some potentially significant research topics are discussed which might be successfully attacked in the university atmosphere

    Reduction of low- and high-grade cervical abnormalities associated with high uptake of the HPV bivalent vaccine in Scotland

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    In Scotland, a national HPV immunisation programme began in 2008 for 12-13 year olds, with a catch-up campaign from 2008-2011 for those under the age of 18. To monitor the impact of HPV immunisation on cervical disease at the population level, a programme of national surveillance was established.  We analysed colposcopy data from a cohort of women born between 1988-1992 who entered the Scottish Cervical Screening Programme (SCSP) and were aged 20-21 in 2008-2012.  By linking datasets from the SCSP and colposcopy services, we observed a significant reduction in diagnoses of cervical intraepithelial neoplasia 1 (CIN 1) (RR 0.71, 95% CI 0.58 to 0.87, p=0.0008), CIN 2 (RR 0.5, 95% CI 0.4, 0.63, p<0.0001) and CIN 3 (RR 0.45, 95% CI 0.35 to 0.58, p< 0.0001) for women who received 3 doses of vaccine compared with unvaccinated women.  To our knowledge, this is one of the first studies to show a reduction of low and high grade cervical intraepithelial neoplasia associated with high uptake of the HPV bivalent vaccine at the population level. These data are very encouraging for countries that have achieved high HPV vaccine uptake

    The impact of post-abortion care family planning counselling and services in low-income countries: a systematic review of the evidence

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    Unsafe abortions account for around 70,000 deaths each year, almost all of them in the developing world. Millions of women suffer permanent injury or chronic illness, adding a high cost to both individual families and health systems. Since the mid 1990s, post-abortion care has become a central part of the international strategy to address this problem. Although most attention has been paid to improving emergency treatment of abortion complications, the other elements of post-abortion care, including providing family planning counselling and services, have also been promoted and can be found in many health-care settings around the world. Although greater use of contraception will not produce direct, immediate effects on maternal mortality or morbidity, over time it should reduce women's recourse to unsafe abortion by preventing unplanned pregnancies, thereby putting women at less risk of lifelong injury or death. In 2010, the UK government strengthened its commitment to family planning as a strategy to reduce maternal mortality, marking a significant shift in the UK‟s approach to addressing the most off-track Millennium Development Goal: to improve material health. Addressing the unmet need for post-abortion family planning counselling and services to prevent repeat unplanned pregnancies remains a key part of the new developments in policy. It is therefore both vital and timely to increase understanding of the impacts of such programmes, in order to ensure that they are effective in delivering positive outcomes for women and provide value for money. This systematic review aimed to identify and synthesise the relevant research literature, thereby contributing to what is a relatively unexamined field. It addressed the question: What is the impact of post-abortion care family planning counselling and services in low-income countries on maternal mortality or morbidity, repeat induced abortions or unplanned pregnancies, or acceptance or use of contraception

    Application of blade-element techniques to design and performance prediction problems for axial-flow turbomachinery Progress report, 1 Apr. - 30 Sep. 1969

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    Noncavitating operation data from different axial flow pump rotor configurations and correlation of flow pump deviation angle

    The Learning Tourism Destination: The potential of a learning organisation approach for improving the sustainability of tourism destinations

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    Globalisation, increasing complexity, and the need to address triple-bottom line sustainability has seen the proliferation of Learning Organisations (LO) who, by definition, have the capacity to anticipate environmental changes and economic opportunities and adapt accordingly. Such organisations use system dynamics modelling (SDM) for both strategic planning and the promotion of organisational learning. Although SDM has been applied in the context of tourism destination management for predictive reasons, the current literature does not analyse or recognise how this could be used as a foundation for an LO. This study introduces the concept of the Learning Tourism Destinations (LTD) and discusses, on the basis of a review of 6 case studies, the potential of SDM as a tool for the implementation and enhancement of collective learning processes. The results reveal that SDM is capable of promoting communication between stakeholders and stimulating organisational learning. It is suggested that the LTD approach be further utilised and explored

    Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin

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    Epithelial tight junctions participate in the regulation of gene expression by controlling the activity of transcription factors that can interact with junctional components. One such protein is the Y-box transcription factor ZONAB/DbpA that binds to ZO-1, a component of the junctional plaque. Symplekin, another nuclear protein that can associate with tight junctions, functions in the regulation of polyadenylation and thereby promotes gene expression. Here, we addressed the question of whether these two proteins interact and whether this is of functional relevance. We demonstrate that ZONAB/DbpA and symplekin form a complex in kidney and intestinal epithelial cells that can be immunoprecipitated and that exists in the nucleus. The interaction between ZONAB/DbpA and symplekin can be reconstituted with recombinant proteins. In reporter gene assays in which ZONAB/DbpA functions as a repressor, symplekin functionally interacts with ZONAB/DbpA, indicating that symplekin can also promote transcriptional repression. RNAi experiments indicate that symplekin depletion reduces the nuclear accumulation and the transcriptional activity of ZONAB/DbpA in colon adenocarcinoma cells, resulting in inhibition of proliferation and reduced expression of the ZONAB/DbpA-target gene cyclin D1. Our data thus indicate that symplekin and ZONAB/DbpA cooperate in the regulation of transcription, and that they promote epithelial proliferation and cyclin D1 expression
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