689 research outputs found
Synchronized single electron emission from dynamical quantum dots
We study synchronized quantized charge pumping through several dynamical
quantum dots (QDs) driven by a single time modulated gate signal. We show that
the main obstacle for synchronization being the lack of uniformity can be
overcome by operating the QDs in the decay cascade regime. We discuss the
mechanism responsible for lifting the stringent uniformity requirements. This
enhanced functionality of dynamical QDs might find applications in
nanoelectronics and quantum metrology.Comment: 4 pages, 3 figures, submitted to AP
Robust single-parameter quantized charge pumping
This paper investigates a scheme for quantized charge pumping based on
single-parameter modulation. The device was realized in an AlGaAs-GaAs gated
nanowire. We find a remarkable robustness of the quantized regime against
variations in the driving signal, which increases with applied rf power. This
feature together with its simple configuration makes this device a potential
module for a scalable source of quantized current.Comment: Submitted to Appl. Phys. Let
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis
Summary
Axial mesendoderm is comprised of prechordal plate and notochord. Lack of a suitable Cre driver has hampered the ability to genetically dissect the requirement for each of these components, or genes expressed within them, to anterior patterning. Here, we have utilized Isl1-Cre to investigate roles of the winged helix transcription factor Foxa2 specifically in prechordal plate and ventral endoderm. Foxa2loxP/loxP; Isl1-Cre mutants died at 13.5 dpc, exhibiting aberrations in anterior neural tube and forebrain patterning, and in ventral foregut morphogenesis and cardiac fusion. Molecular analysis of Foxa2loxP/loxP; Isl1-Cre mutants indicated that Foxa2 is required in Isl1 lineages for expression of notochord and dorsal foregut endoderm markers, Shh. Brachyury, and Hlxb9. Our results support a requirement for Foxa2 in prechordal plate for notochord morphogenesis, axial patterning, and patterning of dorsal foregut endoderm. Loss of Foxa2 in ventral endoderm resulted in reduced expression of Sox17, Gata4, and ZO proteins, accounting at least in part for observed lack of foregut fusion, cardia bifida, and increased apoptosis of ventral endoderm
Constructive role of non-adiabaticity for quantized charge pumping
We investigate a recently developed scheme for quantized charge pumping based
on single-parameter modulation. The device was realized in an AlGaAl-GaAs gated
nanowire. It has been shown theoretically that non-adiabaticity is
fundamentally required to realize single-parameter pumping, while in previous
multi-parameter pumping schemes it caused unwanted and less controllable
currents. In this paper we demonstrate experimentally the constructive and
destructive role of non-adiabaticity by analysing the pumping current over a
broad frequency range.Comment: Presented at ICPS 2010, July 25 - 30, Seoul, Kore
Edge spin accumulation in semiconductor two-dimensional hole gases
The controlled generation of localized spin densities is a key enabler of
semiconductor spintronics In this work, we study spin Hall effect induced edge
spin accumulation in a two-dimensional hole gas with strong spin orbit
interactions. We argue that it is an intrinsic property, in the sense that it
is independent of the strength of disorder scattering. We show numerically that
the spin polarization near the edge induced by this mechanism can be large, and
that it becomes larger and more strongly localized as the spin-orbit coupling
strength increases, and is independent of the width of the conducting strip
once this exceeds the elastic scattering mean-free-path. Our experiments in
two-dimensional hole gas microdevices confirm this remarkable spin Hall effect
phenomenology. Achieving comparable levels of spin polarization by external
magnetic fields would require laboratory equipment whose physical dimensions
and operating electrical currents are million times larger than those of our
spin Hall effect devices.Comment: 6 pages, 5 figure
Artificial neural networks for 3D cell shape recognition from confocal images
We present a dual-stage neural network architecture for analyzing fine shape
details from microscopy recordings in 3D. The system, tested on red blood
cells, uses training data from both healthy donors and patients with a
congenital blood disease. Characteristic shape features are revealed from the
spherical harmonics spectrum of each cell and are automatically processed to
create a reproducible and unbiased shape recognition and classification for
diagnostic and theragnostic use.Comment: 17 pages, 8 figure
Phase Structure of Z(3)-Polyakov-Loop Models
We study effective lattice actions describing the Polyakov loop dynamics
originating from finite-temperature Yang-Mills theory. Starting with a
strong-coupling expansion the effective action is obtained as a series of
Z(3)-invariant operators involving higher and higher powers of the Polyakov
loop, each with its own coupling. Truncating to a subclass with two couplings
we perform a detailed analysis of the statistical mechanics involved. To this
end we employ a modified mean field approximation and Monte Carlo simulations
based on a novel cluster algorithm. We find excellent agreement of both
approaches concerning the phase structure of the theories. The phase diagram
exhibits both first and second order transitions between symmetric,
ferromagnetic and anti-ferromagnetic phases with phase boundaries merging at
three tricritical points. The critical exponents nu and gamma at the continuous
transition between symmetric and anti-ferromagnetic phases are the same as for
the 3-state Potts model.Comment: 20 pages, 22 figure
Single-parameter quantized charge pumping in high magnetic fields
We study single-parameter quantized charge pumping via a semiconductor
quantum dot in high magnetic fields. The quantum dot is defined between two top
gates in an AlGaAs/GaAs heterostructure. Application of an oscillating voltage
to one of the gates leads to pumped current plateaus in the gate
characteristic, corresponding to controlled transfer of integer multiples of
electrons per cycle. In a perpendicular-to-plane magnetic field the plateaus
become more pronounced indicating an improved current quantization. Current
quantization is sustained up to magnetic fields where full spin polarization of
the device can be expected.Comment: This article has been submitted to Applied Physics Letter
Single-parameter non-adiabatic quantized charge pumping
Controlled charge pumping in an AlGaAs/GaAs gated nanowire by
single-parameter modulation is studied experimentally and theoretically.
Transfer of integral multiples of the elementary charge per modulation cycle is
clearly demonstrated. A simple theoretical model shows that such a quantized
current can be generated via loading and unloading of a dynamic quasi-bound
state. It demonstrates that non-adiabatic blockade of unwanted tunnel events
can obliterate the requirement of having at least two phase-shifted periodic
signals to realize quantized pumping. The simple configuration without multiple
pumping signals might find wide application in metrological experiments and
quantum electronics.Comment: 4 pages, 4 figure
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