Apollo 7 retrofire and reentry of service propulsion module. Further study of Intelsat 2 F-2 apogee burn

Photography of Apollo 7 retrofire and service propulsion module reentry and apogee burn of Intelsat 2 F-2 satellit

Correlative Spectromicroscopy and Tomography for Biomedical Applications involving Electron, Ion, and Soft X-ray Microscopies

Many important scientific and technical problems are best addressed using multiple, microscopy-based analytical techniques that combine the strengths of complementary methods. Here, we provide two examples from biomedical challenges: unravelling the attachment zone between dental implants and bone, and uncovering the mechanism of Alzheimer's disease. They combine synchrotron-based scanning transmission X-ray microscopy (STXM) with transmission electron microscopy ((S)TEM), electron tomography (ET), EELS tomography, and/or atom probe tomography (APT). STXM provides X-ray absorption based chemical sensitivity at mesoscale resolution (10–30 nm), which complements higher spatial resolution electron microscopy and APT

Drug release from polymer-coated TiO2nanotubes on additively manufactured Ti-6Al-4V bone implants: a feasibility study

Insufficient osseointegration, inflammatory response and bacterial infection are responsible for the majority of bone implant failures. Drug-releasing implants subjected to adequate surface modification can concurrently address these challenges to improve the success of implant surgeries. This work investigates the use of Ti-6Al-4V (Ti64) with a dual-scale surface topography as a platform for local drug delivery. Dual-scale topography was obtained combining the inherent microscale roughness of the Ti64 samples manufactured by selective laser melting (SLM) with the nanoscale roughness of TiO2 nanotubes (TNTs) obtained by subsequent electrochemical anodization at 60 V for 30 min. TNTs were loaded with a solution of penicillin-streptomycin, a common antibiotic, and drug release was tested in vitro. Three biocompatible and biodegradable polymers, i.e. chitosan, poly(ϵ-caprolactone) and poly(3-hydroxybutyrate), were deposited by spin coating, while preserving the microscale topography of the substrate underneath. The presence of polymer coatings overall modified the drug release pattern, as revealed by fitting of the experimental data with a power-law model. A slight extension in the overall duration of drug release (about 17% for a single layer and 33% for two layers of PCL and PHB) and reduced burst release was observed for all polymer-coated samples compared to uncoated, especially when two layers of coatings were applied

Stress induced defect formation in DC cast magnesium alloys

The horizontal direct chill (HDC) casting process is emerging as an attractive production route for magnesium remelt ingot. The CRC for Alloy and Solidification Technology (CAST) has performed significant development work to facilitate HDC casting of magnesium and its alloys. This paper reports the results of a study of the defects that may form during HDC casting of pure magnesium and alloy AZ91. Depending on the operating conditions and alloy cast, the ingot may sometimes display surface cracks and classic centreline DC casting hot cracks. The formation of these defects restrics productivity and casting quality and may also represent a significant safety hazard during HDC casting or in remelting the magnesium ingot. It is shown that both surface cracks and hot tears are related to the rupture of the partially solidified material as a consequence of the development of excessive stresses during casting. The process behaviour in terms of heat flow, sump profile and solidification mode has therefore been determined to enable the identification and prediction of the root causes of these defects during HDC casting of both pure magnesium and AZ91 under different casting conditions. Inspection of the cracks indicates that they have both formed while the alloy was in a partly solidified condition. The mechanisms leading to stress development in the ingot are discussed and related to the development of strength in the mushy zone during solidification

Visualizing biointerfaces in three dimensions: electron tomography of the bone–hydroxyapatite interface

A positive interaction between human bone tissue and synthetics is crucial for the success of bone-regenerative materials. A greater understanding of the mechanisms governing bone-bonding is often gained via visualization of the bone–implant interface. Interfaces to bone have long been imaged with light, X-rays and electrons. Most of these techniques, however, only provide low-resolution or two-dimensional information. With the advances in modern day transmission electron microscopy, including new hardware and increased software computational speeds, the high-resolution visualization and analysis of three-dimensional structures is possible via electron tomography. We report, for the first time, a three-dimensional reconstruction of the interface between human bone and a hydroxyapatite implant using Z-contrast electron tomography. Viewing this structure in three dimensions enabled us to observe the nanometre differences in the orientation of hydroxyapatite crystals precipitated on the implant surface in vivo versus those in the collagen matrix of bone. Insight into the morphology of biointerfaces is considerably enhanced with three-dimensional techniques. In this regard, electron tomography may revolutionize the approach to high-resolution biointerface characterization

Experimental determination of heat transfer across the metal/mold gap in a direct chill (DC) casting mold—part I: Effect of gap size and mold gas type

An experimental apparatus to determine the heat-transfer coefficient in the gap formed between the cast metal and the mold wall of a vertical direct chill (DC) casting mold is described. The apparatus simulates the conditions existing within the confines of the DC casting mold and measures the heat flux within the gap. Measurements were made under steady-state conditions, simulating the steady-state regime of the DC casting process. A range of casting parameters that may affect the heat transfer was tested using this apparatus. In the current article, the operation of the apparatus is described along with the results for the effect of gas type within the mold, and the size of the metal-mold gap formed during casting. The results show that the gas type and the gap size significantly affect the heat transfer within a DC casting mold. The measured heat fluxes for all the conditions tested were expressed as a linear correlation between the heat-transfer coefficient and the metal-mold gap size, and the fluxes can be used to estimate the heat transfer between the metal and the mold at any gap size. These results are compared to values reported in the literature and recommendations are made for the future reporting of the metal/mold heat-transfer coefficient for DC casting. The results for the effect of the other parameters tested are described in Part II of the article