A Fuzzy Spatio-Temporal-based Approach for Activity Recognition

International audienceOver the last decade, there has been a significant deployment of systems dedicated to surveillance. These systems make use of real-time sensors that generate continuous streams of data. Despite their success in many cases, the increased number of sensors leads to a cognitive overload for the operator in charge of their analysis. However, the context and the application requires an ability to react in real-time. The research presented in this paper introduces a spatio-temporal-based approach the objective of which is to provide a qualitative interpretation of the behavior of an entity (e.g., a human or vehicle). The process is formally supported by a fuzzy logic-based approach, and designed in order to be as generic as possible

Comparison of the Safety and Pharmacokinetics of ST-246® after IV Infusion or Oral Administration in Mice, Rabbits and Monkeys

ST-246® is an antiviral, orally bioavailable small molecule in clinical development for treatment of orthopoxvirus infections. An intravenous (IV) formulation may be required for some hospitalized patients who are unable to take oral medication. An IV formulation has been evaluated in three species previously used in evaluation of both efficacy and toxicology of the oral formulation. plasma concentrations. These effects were eliminated using slower IV infusions. associated toxicity. Shorter infusions at higher doses in NHP resulted in decreased clearance, suggesting saturated distribution or elimination. Elimination half-lives in all species were similar between oral and IV administration. The administration of ST-246 was well tolerated as a slow IV infusion

Short-Pulse Effects in Fir Optical Saturation - Shallow Donors in Silicon

Optical saturation experiments are widely used to determine the lifetime T1 of photoexcited states. Unfortunately, such experiments require the simultaneous knowledge of the phase relaxation time T2 and an absolute calibration of the light intensity I in the sample, rendering the analysis of such experiments hazardous. The present contribution illustrates how this problem can be solved by using free electron lasers like FELIX yielding trains of short pulses instead of quasi-cw radiation

Free-Electron Laser-Induced Bleaching of the Intersubband Absorption in Semiconductor Quantum-Wells

The intensity dependent intersubband absorption in GaAs/AlGaAs quantum wells with a subband separation smaller than the optical phonon energy has been measured with a pulsed far infrared free electron laser (FELIX). Complete bleaching of the absorption is observed at I = 100 kW/cm2. When fitted with a two-level system, the saturation intensity is found to be 10 kW/CM2, which corresponds to a characteristic time constant of 1-2 ps. Possible interpretations are discussed in the situation of finite FEL pulse width

Cross-sectional evaluation of the sarcopenia quality of life (Sarqol) questionnaire: Translation and validation of its psychometric properties

Background: The SarQoL, a quality-of-life questionnaire specific to sarcopenia, was developed in 2015 and has since been translated into a number of other languages. The main reason to introduce this new Ukrainian version of the questionnaire was to measure sarcopenic individuals’ perceptions regarding their positions in life in the context of their culture and value systems. Methods: The questionnaire was translated using a forward-backward approach with a pre-test. A total of 49 participants were recruited for the validation study. Sarcopenia was diagnosed according to the Ishii test. The validation analyses included discriminative power, internal consistency, floor and ceiling effects, construct validity, and test-retest reliability. We compared the SarQoL questionnaire to the Short-Form 36 and the EuroQoL-5 Dimensions. Results: A total of 28 participants out of 49 were categorized as probably sarcopenic. They had a significantly lower quality of life (overall score 58.43±17.13 vs. 69.89±13.31; p=0.014). The internal consistency was excellent (α=0.898), with none of the domains showing a disproportionate influence on the homogeneity of the questionnaire. Convergent construct validity was also confirmed. The results indicated a near-perfect degree of test-retest reliability. Conclusions: The first Ukrainian version of the questionnaire is equivalent to the available original English version. © 2020 by The Korean Geriatrics Society