Design And Construction Of Low Power, Portable Photocatalytic Water Treatment Unit Using Light Emitting Diode

Limited availability of mobile technology to disinfect drinking water at low cost led to the current research of using titanium dioxide (TiO2) photocatalysis for drinking water disinfection. New UV light emitting diodes (LEDs) have potential for application in this technology. The research was divided into three parts: immobilization of TiO2, optimization of coating and reactor using methyl orange and investigating disinfection efficiency for Escheriachia coli (ATCC 25922). Thin TiO2 films supplemented with Degussa P25, coated on glass beads and calcinated at 500 oC had 9.9 mm maximum and 2 mm average thickness, 0.28 m2/g BET surface area and was dominated by the anatase TiO2 phase. A reactor with LEDs degraded methyl orange with a first order rate constant of 0.39 hr-1 and 3 log10 E. coli removal was noted in 240 mins. With anticipated drops in LED cost, use of LEDs for TiO2 photocatalysis remains a promising disinfection technology

Temperature analysis for lake Yojoa, Honduras

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2006.Includes bibliographical references (p. 84-90).Lake Yojoa is the largest freshwater lake in Honduras, located in the central west region of the country (1405' N, 88° W). The lake has a surface area of 82 km2, a maximum depth of 26 m. and an average depth of 16 m. The locals believe that the anthropogenic activities around the lake for the past 25 years have impacted the water quality of the lake. Temperature analysis of the lake helps to understand the seasonal changes in the thermal structure of the lake, and it also indicates the seasonal changes in the water quality of the lake. The lake is marginally stratified most of the year, with a maximum difference of 4°C between the water surface and the lake bottom. The temporal changes in the thermal structure of the lake are studied using the lake stability analysis and a temperature model CE-THERM. The two analyses confirm that the lake overturns once a year. However, they differ on the onset of the overturn event and the seasonal changes in the stratification depth. The stability analysis indicates an overturn in November and for some years less stable lake conditions in June. The CE-THERM model was run for year 2005 and it indicates a possible overturn in June, and the lake remaining mixed until December.(cont.) Further analysis using additional data is recommended to improve the temperature model predictions. Higher wind speeds, and lower air temperature were observed during the October and November time period, their combined effect appears to be mixing the lake. The inflow water is about 3 °C colder than the lake surface for most of the year, and it tends to sink in the bottom of the lake water column. Poor quality of inflow water settling in the bottom of the lake during a sudden overturn event can cause negative consequences on the dissolved oxygen of the lake, and thus the aquatic processes depending on it. Further studies are recommended to study the transport of the inflowing waters and their circulation in the lake water column, especially during the periods of low stability. Additionally, the thermal analysis can be extended to analyze other water quality constituents, and ultimately leading to the study of eutrophication.by Mira Chokshi.M.Eng

Contrasting histoarchitecture of calcified leaflets from stenotic bicuspid versus stenotic tricuspid aortic valves

AbstractPreliminary findings from clinical trials of percutaneous balloon aortic valvuloplasty and intraoperative debridement of calcific deposits in patients with aortic stenosis have suggested that calcified, congenitally bicuspid aortic valves may be less amenable to these techniques than are calcified tricuspid aortic valves. Accordingly, we evaluated the histoarchitecture of calcific deposits in 30 operatively excised aortic valves. Light microscopic sections taken through the calcified aortic valve leaflets disclosed two principal types of histoarchitectitre. In 11 aortic valves nodular calcific deposits were superimposed on an underlying fibrotic aortic valve leaflet (type A); in 17 valves calcific deposits were diffusely distributed throughout the body (spongiosa) of the aortic valve leaflets (type B). Two aortic valves could not be classified histologically.These histologic subtypes were not randomly distributed with regard to gross valvular morphology. All 14 bicuspid valves (100%) were type B; in contrast, 11 (69%) of 16 tricuspld aortic valves were type A, and only 3 (19%) of 16 tricuspid valves were type B (p < 0.01). Both valves with nonclassifiable histologic features were tricuspid on the basis of gross examination.Thus, the histoarchitectural distribution of calcific deposits is different for bicuspid than for tricuspid stenotic aortic valves. The more diffuse distribution of calcium throughout the body of calcified bicuspid aortic valve leaflets may render these valves less amenable to operative and percutaneous valvuloplasty than are calcified tricuspid aortic valve leaflets on which calcific deposits are typically superimposed in nodular form

The mass density in black holes inferred from the X-ray background

The X-ray Background (XRB) probably originates from the integrated X-ray emission of active galactic nuclei (AGN). Modelling of its flat spectrum implies considerable absorption in most AGN. Compton down-scattering means that sources in which the absorption is Compton thick are unlikely to be major contributors to the background intensity so the observed spectral intensity at about 30 keV is little affected by photoelectric absorption. Assuming that the intrinsic photon index of AGN is 2, we then use the 30 keV intensity of the XRB to infer the absorption-corrected energy density of the background. Soltan's argument then enables us to convert this to a mean local density in black holes, assuming an accretion efficiency of 0.1 and a mean AGN redshift of 2. The result is within a factor of two of that estimated by Haehnelt et al from the optically-determined black hole masses of Magorrian et al. We conclude that there is no strong need for any radiatively inefficient mode of accretion for building the masses of black holes. Furthermore we show that the absorption model for the XRB implies that about 85 per cent of accretion power in the Universe is absorbed. This power probably emerges in the infrared bands where it can be several tens per cent of the recently inferred backgrounds there. The total power emitted by accretion is then about one fifth that of stars.Comment: 4 pages, accepted for publication in MNRA

Geodesic motions versus hydrodynamic flows in a gravitating perfect fluid: Dynamical equivalence and consequences

Stimulated by the methods applied for the observational determination of masses in the central regions of the AGNs, we examine the conditions under which, in the interior of a gravitating perfect fluid source, the geodesic motions and the general relativistic hydrodynamic flows are dynamically equivalent to each other. Dynamical equivalence rests on the functional similarity between the corresponding (covariantly expressed) differential equations of motion and is obtained by conformal transformations. In this case, the spaces of the solutions of these two kinds of motion are isomorphic. In other words, given a solution to the problem "hydrodynamic flow in a perfect fluid", one can always construct a solution formally equivalent to the problem "geodesic motion of a fluid element" and vice versa. Accordingly, we show that, the observationally determined nuclear mass of the AGNs is being overestimated with respect to the real, physical one. We evaluate the corresponding mass-excess and show that it is not always negligible with respect to the mass ofthe central dark object, while, under circumstances, can be even larger than the rest-mass of the circumnuclear gas involved.Comment: LaTeX file, 22 page

Self-medication amongst pregnant women in a tertiary care teaching hospital in India

Background: Self-medication is a popular practice in developing countries where there is no strict regulation of drugs sold in local pharmacies. General public is usually unaware of the adverse effects of drugs used for common illness and continue using them without prescription during pregnancy. This study was carried out to know the extent of self-medication practised by pregnant women and various factors associated with it.Methods: A questionnaire based, cross-sectional study of pregnant women visiting the OB GYN-OPD of a tertiary care teaching hospital was conducted. 303 eligible subjects were questioned and statistical analysis was carried out.Results: Total 16.5% women were found to be self-medicating during pregnancy for common conditions like headache (26%), fever (23%) and common cold (19%). Odds Ratio between the self-medicating and non-self-medicating groups for variables like age (<25 years; ≥25 years), education (illiterate; literate) and gestational age (<20 weeks; ≥20 weeks) are 1.6, 2 and 1.73 respectively. Women with a history of self-medicating before pregnancy were significantly more likely to continue doing so during pregnancy (p value <0.00001).Conclusions: A significant proportion of pregnant women have been found to self-medicate without knowing the adverse effects of the drug used. Thus, spreading awareness against this health-predicament is necessary

MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis.

The importance of epigenetic changes in the development of hepatic steatosis is largely unknown. The histone variant macroH2A1 under alternative splicing gives rise to macroH2A1.1 and macroH2A1.2. In this study, we show that the macroH2A1 isoforms play an important role in the regulation of lipid accumulation in hepatocytes. Hepatoma cell line and immortalized human hepatocytes transiently transfected or knocked down with macroH2A1 isoforms were used as in vitro model of fat-induced steatosis. Gene expressions were analyzed by quantitative PCR array and Western blot. Chromatin immunoprecipitation analysis was performed to check the association of histone H3 lysine 27 trimethylation (H3K27me3) and histone H3 lysine 4 trimethylation (H3K4me3) with the promoter of lipogenic genes. Livers from knockout mice that are resistant to lipid deposition despite a high-fat diet were used for histopathology. We found that macroH2A1.2 is regulated by fat uptake and that its overexpression caused an increase in lipid uptake, triglycerides, and lipogenic genes compared with macroH2A1.1. This suggests that macroH2A1.2 is important for lipid uptake, whereas macroH2A1.1 was found to be protective. The result was supported by a high positivity for macroH2A1.1 in knockout mice for genes targeted by macroH2A1 (Atp5a1 and Fam73b), that under a high-fat diet presented minimal lipidosis. Moreover, macroH2A1 isoforms differentially regulate the expression of lipogenic genes by modulating the association of the active (H3K4me3) and repressive (H3K27me3) histone marks on their promoters. This study underlines the importance of the replacement of noncanonical histones in the regulation of genes involved in lipid metabolism in the progression of steatosis

Massive Ellipticals at High Redshift: NICMOS Imaging of Z~1 Radio Galaxies

We present deep, continuum images of eleven high-redshift (0.811 < z < 1.875) 3CR radio galaxies observed with NICMOS. Our images probe the rest-frame optical light where stars are expected to dominate the galaxy luminosity. The rest-frame UV light of eight of these galaxies demonstrates the well-known ``alignment effect''. Most of the radio galaxies have rounder, more symmetric morphologies at rest-frame optical wavelengths. Here we show the most direct evidence that in most cases the stellar hosts are normal elliptical galaxies with de Vaucouleurs law light profiles. For a few galaxies very faint traces of the UV-bright aligned component are also visible in the infrared images. We derive both the effective radius and surface-brightness for nine of eleven sample galaxies by fitting surface-brightness models to them. We find their sizes are similar to those of local FRII radio source hosts and are in general larger than other local galaxies. The derived host galaxy luminosities are very high and lie at the bright end of luminosity functions constructed at similar redshifts. The galaxies in our sample are also brighter than the rest-frame size--surface-brightness locus defined by the low-redshift sources. Passive evolution roughly aligns the z ~ 1 galaxies with the low-redshift samples. The optical host is sometimes centered on a local minimum in the rest-frame UV emission, suggesting the presence of substantial dust obscuration. We also see good evidence of nuclear point sources in three galaxies. Overall, our results are consistent with the hypothesis that these galaxies have already formed the bulk of their stars at redshifts greater than z >~ 2, and that the AGN phenomenon takes place within otherwise normal, perhaps passively evolving, galaxies. (abridged)Comment: 28 pages, 14 figures, accepted to ApJ. Uses AASTEX and emulateapj

Review of public comments on proposed seismic design criteria

During the first quarter of 1988, the Nuclear Regulatory Commission (NRC) prepared a proposed Revision 2 to the NUREG-0800 Standard Review Plan (SRP) Sections 2.5.2 (Vibratory Ground Motion), 3.7.1 (Seismic Design Parameters), 3.7.2 (Seismic Systems Analysis) and 3.7.3 (Seismic Subsystem Analysis). The proposed Revision 2 to the SRP was a result of many years' work carried out by the NRC and the nuclear industry on the Unresolved Safety Issue (USI) A-40: ''Seismic Design Criteria.'' The background material related to NRC's efforts for resolving the A-40 issue is described in NUREG-1233. In June 1988, the proposed Revision 2 of the SRP was issued by NRC for public review and comments. Comments were received from Sargent and Lundy Engineers, Westinghouse Electric Corporation, Stevenson and Associates, Duke Power Company, General Electric Company and Electric Power Research Institute. In September 1988, Brookhaven National Laboratory (BNL) and its consultants (C.J. Costantino, R.P. Kennedy, J. Stevenson, M. Shinozuka and A.S. Veletsos) were requested to carry out a review of the comments received from the above six organizations. The objective of this review was to assist the NRC staff with the evaluation and resolution of the public comments. This review was initiated during October 1988 and it was completed on January 1989. As a result of this review, a set of modifications to the above mentioned sections of the SRP were recommended by BNL and its consultants. This paper summarizes the recommended modifications. 4 refs

Intergalactic Magnetic Fields from Quasar Outflows

Outflows from quasars inevitably pollute the intergalactic medium (IGM) with magnetic fields. The short-lived activity of a quasar leaves behind an expanding magnetized bubble in the IGM. We model the expansion of the remnant quasar bubbles and calculate their distribution as a function of size and magnetic field strength at different redshifts. We generically find that by a redshift z=3, about 5-20% of the IGM volume is filled by magnetic fields with an energy density >10% of the mean thermal energy density of a photo-ionized IGM (at T=10^4 K). As massive galaxies and X-ray clusters condense out of the magnetized IGM, the adiabatic compression of the magnetic field could result in the field strength observed in these systems without a need for further dynamo amplification. The intergalactic magnetic field could also provide a nonthermal contribution to the pressure of the photo-ionized gas that may account for the claimed discrepancy between the simulated and observed Doppler width distributions of the Ly-alpha forest.Comment: 40 pages, 8 figures, submitted to Ap