Some theorems on the explicit evaluations of singular moduli

At scattered places in his notebooks, Ramanujan recorded some theorems for calculating singular moduli and also recorded several values of singular moduli. In this paper, we establish several general theorems for the explicit evaluations of singular moduli. we also obtain some values of class invariants and singular moduli

A prospective study to analyse antibiotic susceptibility pattern of Pseudomonas aeruginosa in a tertiary care hospital

Background: Pseudomonas aeruginosa, a gram-negative pathogen is commonly associated with nosocomial infections. Infections caused by P. aeruginosa can range from superficial skin infections to fulminant sepsis. Antimicrobial resistance is an area of prime concern in pseudomonal infections. The objective of the study was to evaluate and analyse the antibiotic susceptibility pattern of P. aeruginosa at a tertiary care hospital in South India.Methods: The study was carried out at Kasturba Medical College and Hospital, Manipal, India from January 2011 to December 2011. Ten different types of specimens were collected from patients who were culture positive for Pseudomonas aeruginosa. Antibiotic susceptibility was confirmed by disk diffusion technique on Muller-Hinton medium and was performed according to the Clinical Laboratory Standard Institute (CLSI) guidelines.Results: Out of 200 samples of P. aeruginosa 69.5% and 30.5% were from male and female patients respectively. Majority of the specimen from which P. aeruginosa was isolated consisted of sputum, pus and urine. Among the antimicrobial drugs tested, organism was most sensitive to carbapenems (77.5%), piperacillin-tazobactam (77%) and cefoperazone-sulbactam (72%). Resistance rates were high for fluoroquinolones (FQs) (43.5%), gentamicin (40.5%), tobramycin (40.5%), ticarcillin-clavulanic acid (39%) and aztreonam (38%) when compared to cefepime (31.5%), ceftazidime (32.5%), netilmicin (34.5%) and amikacin (35%).Conclusions: Carbapenems and piperacillin-tazobactam were the best antipseudomonal agents with highest sensitivity to P. aeruginosa. FQs, gentamicin and tobramycin were the least effective drugs against P. aeruginosa as monotherapy

Bacterial ‘Cell’ Phones: Do cell phones carry potential pathogens?

Cell phones are important companions for professionals especially health care workers (HCWs) for better communication in hospital. The present study compared the nature of the growth of potentially pathogenic bacterial flora on cell phones in hospital and community. 75% cell phones from both the categories grew at least one potentially pathogenic organism. Cell phones from HCWs grew significantly more potential pathogens like MRSA (20%), Acinetobacter species (5%), Pseudomonas species (2.5%) as compared to the non HCWs. 97.5% HCWs use their cell phone in the hospital, 57.5% never cleaned their cell phone and 20% admitted that they did not wash their hands before or after attending patients, although majority (77.5%) knows that cell phones can have harmful colonization and act as vector for nosocomial infections. It is recommended, therefore, that cell phones in the hospital should be regularly decontaminated. Moreover, utmost emphasis needs to be paid to hand washing practices among HCWs

Zincovit syrup ameliorates oxidative stress induced by carbon tetrachloride in rats

Background: Zincovit (ZVT) syrup is a combined formulation of vitamins, minerals and lysine. The present study was aimed to investigate the in vivo antioxidant potential of ZVT syrup in carbon tetrachloride (CCl4) intoxicated Wistar rats.Methods: A total of 36 Wistar rats were divided into six groups of six rats each. Antioxidant potential of ZVT syrup at the dose of 15 mg/kg/day, 30 mg/kg/day and 60 mg/kg/day was evaluated in CCl4 intoxicated rats. The extent of CCl4 induced oxidative stress was studied by estimating malondialdehyde (MDA), glutathione-S-transferase (GST) and catalase (CAT).Results: Oral treatment with ZVT syrup, especially at the dose of 30 mg/kg/day and 60 mg/kg/day reversed CCl4 - induced alterations in MDA (p<0.05), GST (p<0.01) and CAT (p<0.01) compared to CCl4 intoxicated control (untreated) animals.Conclusion: The present findings revealed that ZVT syrup may be useful in oxidative stress associated tissue damage as a nutritional food supplement

A 45-DAY RANDOMIZED, OPEN-LABEL, COMPARATOR STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ZINCOVIT TABLETS WITH GRAPE SEED EXTRACT (NUTRITIONAL FOOD SUPPLEMENT) IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

ABSTRACTObjective: To evaluate the efficacy of Zincovit (ZVT) tablets with grape seed extract (GSE) in patients with Type 2 diabetes mellitus by testing thehypothesis of a greater reduction in plasma glucose levels (fasting blood sugar [FBS] and post-prandial blood sugar [PPBS]) from baseline and after45 days of therapy as compared to standard comparator.Methods: This was a randomized, open-label, comparative (2-arm), prospective 45 days study. Treatment consisted of 2 arms: Antidiabetic drugplus non-pharmacological measure alone or ZVT tablets with GSE plus non-pharmacological measures. A total of 30 patients (15 in each arm) wereincluded in the study.Results: ZVT tablet did not alter the FBS, PPBS, and HbA1c level in diabetic patients compared to diabetic patients treated with placebo. No changeswere seen in any of the safety parameters when given for 45 days.Conclusion: ZVT tablets do not possess antidiabetic activity in spite of good safety profile in our study design. This could be due to several limitationsof the study such as inadequate sample size, short duration of the study, and wrong selection of the patients. A long-term, double-blind, placebocontrolled study in a large sample of population measuring glycemic parameters, and cardiovascular outcomes could give a clear picture of the antidiabeticeffectof ZVT with GSE tablets.Keywords: Diabetes mellitus, Zincovit tablets, Grape seed extract, Antioxidant, Safety parameters

On some explicit evaluations of the ratios of Ramanujan's theta-function.

In this paper, we establish several new modular equations of degree 9 using Ramanujan’s modular equations. We also establish several general formulas for explicit evaluations of h9,n, h0 9,n, l9,n and l 0 9,n. As an application, we establish some explicit evaluations for Ramanujan’s cubic continued fraction

New identities for Ramanujan's cubic continued fraction.

In this paper, we present some new identities providing relations between Ramanujan's cubic continued fraction V(q)V(q) and the other three continued fractions V(q9)V(q9), V(q17)V(q17) and V(q19)V(q19). In the process, we establish some new modular equations for the ratios of Ramanujan's theta functions. We also establish some general formulas for the explicit evaluations of ratios of Ramanujan's theta functions

On some New Identities for Ramanujan'scubic Continued Fraction

In this paper, we establish some new modular relations connecting Ramanujan's cubic continued fraction V (q) with V (qn), for n = 4, 6, 8,10, 12, 14, 16 and 22

On some new identities for Ramanujan's cubic continued fraction.

In this paper, we establish some new modular relations connecting Ramanujan's cubic continued fraction V (q) with V(qn), for n= 4, 6, 8,10, 12, 14, 16 and 22

EVALUATION OF BURN WOUND HEALING ACTIVITY OF TOPICAL REGULAR INSULIN IN NON-DIABETIC AND STREPTOZOCIN-INDUCED DIABETIC RATS

Objective: The role of insulin in the regulation of energy metabolism, protein synthesis, cell differentiation and growth suggests that this hormone could also play an essential role in regulation of wound healing. Consequently, the aim of the present study was to investigate the effects of topical insulin administration on burn wound healing in both non-diabetic and streptozocin-induced diabetic Wistar rats. Methods: Wound healing activity was assessed by burn-wound model. This study was conducted using six groups of Wistar strain adult rats of either sex (n = 6). First three groups were non-diabetic (ND) rats and the other three had diabetic (D) rats: (i) ND control (sterile water); (ii) ND standard (silver sulfadiazine cream); (iii) ND test (topical Insulin); (iv) D control (sterile water); (v) D standard (silver sulfadiazine cream); (vi) D test (topical insulin). Wound healing was assessed by wound contraction rate and complete epithelialization time. Results: There was significant (p&lt;0.05) delay in wound healing in diabetic rats when compared to normal rats. It was found that topical insulin administration enhanced burn wound healing by shortening the time needed for complete epithelialization in the non-diabetic and diabetic group. Conclusion: This study revealed that topical insulin application to partial thickness burn wounds accelerates wound healing in rats with or without acute diabetes