Monitoring Spacecraft Telemetry Via Optical or RF Link

A patent disclosure document discusses a photonic method for connecting a spacecraft with a launch vehicle upper-stage telemetry system as a means for monitoring a spacecraft fs health and status during and right after separation and deployment. This method also provides an efficient opto-coupled capability for prelaunch built-in-test (BIT) on the ground to enable more efficient and timely integration, preflight checkout, and a means to obviate any local EMI (electromagnetic interference) during integration and test. Additional utility can be envisioned for BIT on other platforms, such as the International Space Station (ISS). The photonic telemetry system implements an optical free-space link with a divergent laser transmitter beam spoiled over a significant cone angle to accommodate changes in spacecraft position without having to angle track it during deployment. Since the spacecraft may lose attitude control and tumble during deployment, the transmitted laser beam interrogates any one of several low-profile meso-scale retro-reflective spatial light modulators (SLMs) deployed over the surface of the spacecraft. The return signal beam, modulated by the SLMs, contains health, status, and attitude information received back at the launch vehicle. Very compact low-power opto-coupler technology already exists for the received signal (requiring relatively low bandwidths, e.g., .200 kbps) to enable transfer to a forward pass RF relay from the launch vehicle to TDRSS (Tracking and Data Relay Satellite System) or another recipient. The link would be active during separation and post-separation to monitor spacecraft health, status, attitude, or other data inventories until attitude recovery and ground control can be re-established. An optical link would not interfere with the existing upper stage telemetry and beacon systems, thus meeting launch vehicle EMI environmental constraints

Mucosal Targeting of a BoNT/A Subunit Vaccine Adjuvanted with a Mast Cell Activator Enhances Induction of BoNT/A Neutralizing Antibodies in Rabbits

We previously reported that the immunogenicity of Hcβtre, a botulinum neurotoxin A (BoNT/A) immunogen, was enhanced by fusion to an epithelial cell binding domain, Ad2F, when nasally delivered to mice with cholera toxin (CT). This study was performed to determine if Ad2F would enhance the nasal immunogenicity of Hcβtre in rabbits, an animal model with a nasal cavity anatomy similar to humans. Since CT is not safe for human use, we also tested the adjuvant activity of compound 48/80 (C48/80), a mast cell activating compound previously determined to safely exhibit nasal adjuvant activity in mice.New Zealand White or Dutch Belted rabbits were nasally immunized with Hcβtre or Hcβtre-Ad2F alone or combined with CT or C48/80, and serum samples were tested for the presence of Hcβtre-specific binding (ELISA) or BoNT/A neutralizing antibodies.Hcβtre-Ad2F nasally administered with CT induced serum anti-Hcβtre IgG ELISA and BoNT/A neutralizing antibody titers greater than those induced by Hcβtre + CT. C48/80 provided significant nasal adjuvant activity and induced BoNT/A-neutralizing antibodies similar to those induced by CT.Ad2F enhanced the nasal immunogenicity of Hcβtre, and the mast cell activator C48/80 was an effective adjuvant for nasal immunization in rabbits, an animal model with a nasal cavity anatomy similar to that in humans

Comparison of Macro-Tip/Tilt and Meso-Scale Position Beam-Steering Transducers for Free-Space Optical Communications Using a Quadrant Photodiode Sensor

The National Aeronautics and Space Administration (NASA) plans to develop optical communication terminals for future spacecraft, especially in support of high data rate science missions and manned exploration of Mars. Future, very long-range missions, such as the Realistic Interstellar Explorer (RISE) 1, will need optical downlink communications to enable even very low data rates. For all of these applications, very fine pointing and tracking is also required, with accuracies on the order of ± 1 µrad or less and peak-to-peak ranges of ± 10 mrad or more. For these applications, it will also be necessary to implement very compact, lightweight and low-power precision beam-steering technologies. Although current commercial-off-the-shelf devices, such as macro-scale piezo-driven tip/tilt actuators exist, which approach mission requirements, they are too large, heavy, and power consuming for projected spacecraft mass and power budgets. The Johns Hopkins University Applied Physics Laboratory (JHU/APL) has adopted a different approach to beam-steering in collaboration with the National Institute of Standards and Technology (NIST). We are testing and planning to eventually package a highly accurate large dynamic range meso-scale position transducer under development at NIST. In this paper we will describe a generic package design of an optical communications terminal incorporating the NIST prototype beam-steerer. We will also show test results comparing the performance of the NIST prototyp