Bounds on the Sum Capacity of Synchronous Binary CDMA Channels

In this paper, we obtain a family of lower bounds for the sum capacity of Code Division Multiple Access (CDMA) channels assuming binary inputs and binary signature codes in the presence of additive noise with an arbitrary distribution. The envelope of this family gives a relatively tight lower bound in terms of the number of users, spreading gain and the noise distribution. The derivation methods for the noiseless and the noisy channels are different but when the noise variance goes to zero, the noisy channel bound approaches the noiseless case. The behavior of the lower bound shows that for small noise power, the number of users can be much more than the spreading gain without any significant loss of information (overloaded CDMA). A conjectured upper bound is also derived under the usual assumption that the users send out equally likely binary bits in the presence of additive noise with an arbitrary distribution. As the noise level increases, and/or, the ratio of the number of users and the spreading gain increases, the conjectured upper bound approaches the lower bound. We have also derived asymptotic limits of our bounds that can be compared to a formula that Tanaka obtained using techniques from statistical physics; his bound is close to that of our conjectured upper bound for large scale systems.Comment: to be published in IEEE Transactions on Information Theor

Finite Dimensional Chebyshev Subspaces of Lo

If A is a subset of the normed linear space X, then A is said to be proximinal in X if for each xÎX there is a point y0ÎA such that the distance between x and A; d(x, A) = inf{||x-y||: yÎA}= ||x­-y0||. The element y0 is called a best approximation for x from A. If for each xÎX, the best approximation for x from A is unique then the subset A is called a Chebyshev subset of X.  In this paper the author studies the existence of finite dimensional Chebyshev subspaces of Lo

Flow reversals in turbulent convection via vortex reconnections

We employ detailed numerical simulations to probe the mechanism of flow reversals in two-dimensional turbulent convection. We show that the reversals occur via vortex reconnection of two attracting corner rolls having same sign of vorticity, thus leading to major restructuring of the flow. Large fluctuations in heat transport are observed during the reversal due to this flow reconfiguration. The flow configurations during the reversals have been analyzed quantitatively using large-scale modes. Using these tools, we also show why flow reversals occur for a restricted range of Rayleigh and Prandt numbers

Vortex crystals

Vortex crystals is one name in use for the subject of vortex patterns that move without change of shape or size. Most of what is known pertains to the case of arrays of parallel line vortices moving so as to produce an essentially two-dimensional flow. The possible patterns of points indicating the intersections of these vortices with a plane perpendicular to them have been studied for almost 150 years. Analog experiments have been devised, and experiments with vortices in a variety of fluids have been performed. Some of the states observed are understood analytically. Others have been found computationally to high precision. Our degree of understanding of these patterns varies considerably. Surprising connections to the zeros of 'special functions' arising in classical mathematical physics have been revealed. Vortex motion on two-dimensional manifolds, such as the sphere, the cylinder (periodic strip) and torus (periodic parallelogram) has also been studied, because of the potential applications, and some results are available regarding the problem of vortex crystals in such geometries. Although a large amount of material is available for review, some results are reported here for the first time. The subject seems pregnant with possibilities for further development.published or submitted for publicationis peer reviewe

Viscous evolution of point vortex equilibria: The collinear state

When point vortex equilibria of the 2D Euler equations are used as initial conditions for the corre- sponding Navier-Stokes equations (viscous), typically an interesting dynamical process unfolds at short and intermediate time scales, before the long time single peaked, self-similar Oseen vortex state dom- inates. In this paper, we describe the viscous evolution of a collinear three vortex structure that cor- responds to an inviscid point vortex fixed equilibrium. Using a multi-Gaussian 'core-growth' type of model, we show that the system immediately begins to rotate unsteadily, a mechanism we attribute to a 'viscously induced' instability. We then examine in detail the qualitative and quantitative evolution of the system as it evolves toward the long-time asymptotic Lamb-Oseen state, showing the sequence of topological bifurcations that occur both in a fixed reference frame, and in an appropriately chosen rotating reference frame. The evolution of passive particles in this viscously evolving flow is shown and interpreted in relation to these evolving streamline patterns.Comment: 17 pages, 15 figure

Measles to the Rescue: A Review of Oncolytic Measles Virus

Oncolytic virotherapeutic agents are likely to become serious contenders in cancer treatment. The vaccine strain of measles virus is an agent with an impressive range of oncolytic activity in pre-clinical trials with increasing evidence of safety and efficacy in early clinical trials. This paramyxovirus vaccine has a proven safety record and is amenable to careful genetic modification in the laboratory. Overexpression of the measles virus (MV) receptor CD46 in many tumour cells may direct the virus to preferentially enter transformed cells and there is increasing awareness of the importance of nectin-4 and signaling lymphocytic activation molecule (SLAM) in oncolysis. Successful attempts to retarget MV by inserting genes for tumour-specific ligands to antigens such as carcinoembryonic antigen (CEA), CD20, CD38, and by engineering the virus to express synthetic microRNA targeting sequences, and "blinding" the virus to the natural viral receptors are exciting measures to increase viral specificity and enhance the oncolytic effect. Sodium iodine symporter (NIS) can also be expressed by MV, which enables in vivo tracking of MV infection. Radiovirotherapy using MV-NIS, chemo-virotherapy to convert prodrugs to their toxic metabolites, and immune-virotherapy including incorporating antibodies against immune checkpoint inhibitors can also increase the oncolytic potential. Anti-viral host immune responses are a recognized barrier to the success of MV, and approaches such as transporting MV to the tumour sites by carrier cells, are showing promise. MV Clinical trials are producing encouraging preliminary results in ovarian cancer, myeloma and cutaneous non-Hodgkin lymphoma, and the outcome of currently open trials in glioblastoma multiforme, mesothelioma and squamous cell carcinoma are eagerly anticipated

Propagating phonons coupled to an artificial atom

Quantum information can be stored in micromechanical resonators, encoded as quanta of vibration known as phonons. The vibrational motion is then restricted to the stationary eigenmodes of the resonator, which thus serves as local storage for phonons. In contrast, we couple propagating phonons to an artificial atom in the quantum regime, and reproduce findings from quantum optics with sound taking over the role of light. Our results highlight the similarities between phonons and photons, but also point to new opportunities arising from the unique features of quantum mechanical sound. The low propagation speed of phonons should enable new dynamic schemes for processing quantum information, and the short wavelength allows regimes of atomic physics to be explored which cannot be reached in photonic systems.Comment: 30 pages, 6 figures, 1 tabl