Necrotizing leukocytoclastic vasculitis mimicking necrotizing fasciitis: a case report

There are several subtypes of necrotizing leukocytoclastic vasculitis, which are classified according to their morphological features in biopsy specimens using immunofluorescence microscopy. Necrotizing leukocytoclastic vasculitis is limited to the skin, predominantly that of the lower extremities, and usually spares the palms and soles. The most common skin manifestation is palpable purpura. Other skin manifestations include maculopapular rash, bullae, papules, nodules, ulcers and livedo reticularis. There is no specific laboratory test to determine the diagnosis. There are various diseases presenting with these nonspecific symptoms, and a rapid differential diagnosis must be conducted, because the appropriate differentiation and diagnosis markedly influence the treatment strategy and survival of patients. In this study, we report a case of necrotizing leukocytoclastic vasculitis presenting with internal organ involvement and symptoms of necrotizing fasciitis, with emphasis on the clinical differentiation

Metu-Defocusing Beamline : A 15-30 Mev Proton Irradiation Facility and Beam Measurement System

Middle East Technical University – Defocusing Beam Line (METU-DBL) project is an irradiation facility providing 15 MeV to 30 MeV kinetic energy protons for testing various high radiation level applications, ranging from Hi-Lumi LHC upgrade, space electronic components to nuclear material research. The project located inside the premises of the TAEA (Turkish Atomic Energy Agency) SANAEM (Saraykoy Nuclear Education and Research Center) close to Ankara, provides users a wide selectable flux menu (105–1010 p/cm2/s). The facility is now being commissioned and the facility will be providing a large test area (20 cm x 15 cm) for material, detector and electronics tests. The proton beam is monitored along the beamline using aluminum oxide screens and the flux and uniformity is measured using three detectors attached to the robotic system for cross- checks. A fiber scintillator detector scans the large irradiation area while small area diamond detector and Timepix3 detector are used for spot checks for calibration. Several samples can be radiated simultaneously inside the irradiation area and the robotic system provides 5 separate holders for samples which can be moved in or out, providing users flexibility for the desired fluence. This talk will first introduce METU- DBL as a radiation test facility, then discuss the radiation monitoring of the beam area and the radiation room, while highlighting how this facility can be used for future testing of materials for radiation tolerance

Metu-Defocusing Beamline : A 15-30 Mev Proton Irradiation Facility and Beam Measurement System

Middle East Technical University – Defocusing Beam Line (METU-DBL) project is an irradiation facility providing 15 MeV to 30 MeV kinetic energy protons for testing various high radiation level applications, ranging from Hi-Lumi LHC upgrade, space electronic components to nuclear material research. The project located inside the premises of the TAEA (Turkish Atomic Energy Agency) SANAEM (Saraykoy Nuclear Education and Research Center) close to Ankara, provides users a wide selectable flux menu (105–1010 p/cm2/s). The facility is now being commissioned and the facility will be providing a large test area (20 cm x 15 cm) for material, detector and electronics tests. The proton beam is monitored along the beamline using aluminum oxide screens and the flux and uniformity is measured using three detectors attached to the robotic system for cross- checks. A fiber scintillator detector scans the large irradiation area while small area diamond detector and Timepix3 detector are used for spot checks for calibration. Several samples can be radiated simultaneously inside the irradiation area and the robotic system provides 5 separate holders for samples which can be moved in or out, providing users flexibility for the desired fluence. This talk will first introduce METU- DBL as a radiation test facility, then discuss the radiation monitoring of the beam area and the radiation room, while highlighting how this facility can be used for future testing of materials for radiation tolerance