Transforming knowledge to help others in a global setting.

Jyoti Mishra explains how to transform knowledge to help others in a global setting

Successful detection of an incidental sigmoid injury during laparoscopic surgery by air saline test in a patient of endometrial carcinoma

Laparoscopy has many advantages over open surgery including less post-operative pain, earlier return of normal bowel function, shorter hospital stay, and earlier recovery. Bowel injury is a serious complication of gynecological laparoscopy. The most common site of bowel injury is the small bowel, followed by the large bowel and stomach. This is in agreement with a recent systematic review which has shown that the incidence of bowel injury in gynecologic laparoscopy is 1 in 769.3. Air saline test performed to check bowel integrity by inserting the rectal probe and filling the cavity with normal saline. After performing total laparoscopic hysterectomy with bilateral salphingoopherectomy with retroperitoneal lymphnode dissection done initially after pushing air from rectal probe into the bowel, no bubble was noted but after pushing sigmoid into the pool of saline, escape of air was seen. After suction, a 2×2 cm incidental sigmoidal injury was detected. Bowel injury is a serious complication in laparoscopic surgeries and routine intraoperative checking of bowel integrity by air saline test with the help of rectal probe is a useful modality of intraoperative bowel repair

Diagnosis of static Topology MANETs in faulty environment

Mobile Ad-Hoc Networks (MANETs) are set of mobile nodes that communicates wirelessly without a centralized supporting system. Faulty nodes aect the reliable transmission of messages across the network. In this thesis we deal with the fault identication problem in static topology MANETs. A comparison based approach is used where a set of tasks is given to the nodes and outcomes are compared. Based on these comparisons the nodes are classied either as faulty or fault free. Our new diagnosis model is based on the spanning tree concept in which the testing of the nodes as well as the construction of the spanning tree takes place simultaneously. As a result of which the maintenance and the repairing overhead of the spanning tree is completely avoided thus reducing the number of messages exchanged. We have also developed a simulator which can be applied to a network with large number of nodes.We have carried out the simulation in-order to nd out the total number of messages exchanged and the total diagnosis time. On analysing the results we have seen that our model performs better than its previous counterparts. The correctness and complexity proofs are also being provided which also shows that our model performs better from a communication as well as latency viewpoint

Modelling ill-defined domains using activity theory for semantic augmentation of the social web

This poster describes research concerning modelling ill-defined domains using activity theory for semantic augmentation of the social we

IN VITRO EVALUATION OF THE ANTHELMINTIC ACTIVITY OF RHIZOME EXTRACTS OF CURCUMA LONGA (LINN.)

Objective: The current study was carried out to evaluate the anthelmintic activity of the rhizome extract of Curcuma longa as an alternative source of effective remedies for nematodiasis.Methods: The anthelmintic activity of the C. longa was assessed in vitro against Haemonchus spp., a gastrointestinal (abomasum) parasite of goats. Different concentrations of the extracts (1 mg/mL, 2.5 mg/mL, 5 mg/mL, and 10 mg/mL) in phosphate-buffered saline (PBS) were tested, and the results expressed in terms of time of paralysis (minute) and time of death (minute) of the worms. Albendazole (1 mg/mL) was used as a reference (positive control) and PBS as a control group (negative control).Results: The qualitative phytochemical analysis of the methanolic extract (ME) of the plant disclosed the presence of alkaloids, glycosides, terpenoids, flavonoids, tannins, saponins, phenol, anthraquinone, and carbohydrates; whereas, the aqueous extract (AE) showed the presence of alkaloids, carbohydrate, flavonoids, and saponins. Both ME and AE of the C. longa (rhizome) expressed significant efficacy (p≤0.05) in causing paralysis as well as the death of the worms within 12 h of exposure at all tested concentrations, as compared to the negative control. The rhizome extracts of C. longa showed dose-dependent efficacy in causing paralysis of the worm motility and the final progression to death. The results showed that the ME at 10 mg/mL was significantly more potent (p≤0.05) over the AE.Conclusions: This study concluded that the rhizome extract of C. longa exhibited potent anthelmintic efficacy against the nematode parasite, Haemonchus spp

Assess the acceptance and compliance of injectable contraceptive depot medroxyprogestrone acetate

Background: The use of safe and effective contraception is the need of the hour in India, with one of the world’s largest and fastest growing population. Assessing the acceptance and compliance of women for temporary contraception DMPA. Acceptance shall be compared between different reproductive age group, different parity and among lactating/non lactating female. Methods: In this study, 100 women have been taken, those were appropriate within the inclusion criteria for the period of one year. Injection DMPA 150 mg injected intramuscularly every 3 months and used questionnaire method for assessing the acceptance and compliance of women for temporary contraception DMPA. Results: Injectable contraceptive DMPA is safe, convenient, efficacious and effective long term contraceptive. It is acceptable to women when offered with quality counselling and follow up care. Acceptance of DMPA, was found that there is no need of daily administration of DMPA in 51% of women, 10% women found it’s easy to administer via intramuscular injection, lactating female can breast feed also as it possess no changes in breast milk. Conclusions: DMPA is highly efficacious, safe and effective method of contraception requiring less frequent dosing and can be used in lactating female. Women who received information on DMPA safety, efficacy and side effects are more likely to continue DMPA use

Slackening of Food Supply Chain during COVID-19 and Affecting Livelihood - A Global Concern

The outbreak of COVID-19 has brought about another age on world as the human civilization is restricted in many aspects of everyday lives. There is no exception in the sector of food production and the supply chain of food. Due to constraints on demand, shutting of food production facilities, financial limitations, enterprise operations and delivery of different food items have been interrupted in the food supply chain. Every nation must comprehend the importance of the situation according to the spreading scenario of the ongoing pandemic. The probability of transmission via the food sector is regarded inconsequential, and the public authorities do not believe it necessary to follow COVID into workplaces. The unfavourable effects on the climate, the food framework and the people of the foodstuffs network are evident. An installation for the food supply chain should focus on amenities such as maintaining the safety and health of employees and changing working circumstances. This paper aims at discussing the effects of COVID-19 on the socio-economic status of human being including the negative impacts on the agriculture and food supply chain

Dynamic Spectrum Access: Implications of the diffusion of spectrum sharing technology

This poster describes early research into the impacts of Dynamic Spectrum Access technology and the implications of the diffusion of spectrum sharing technolog

Study of histopathology of endometrium in perimenopausal women with abnormal uterine bleeding

Background: The objective was to evaluate the incidence and prevalence of different histopathological endometrial pattern in patients of abnormal uterine bleeding (AUB) in peri-menopausal women and analyse the type of various menstrual irregularities in AUB cases. Methods: In this study, 164 perimenopausal women aged 41-48 years have been taken having considered appropriate within the inclusion criteria. Histopathological examination was done after obtaining the endometrial curetting’s by Dilatation and curettage or office Pipelle’s canula. Results: Mean age group of subjects was found to be 44.05 years. Majority of subjects were of normal body mass index. Heavy menstrual bleeding was the chief complaint in majority of subjects. Ultrasound finding was leiomyoma in more than 73% subjects. Proliferative pattern of endometrium remained the finding in most of the individuals. Among AUB-M, hyperplasia without atypia occurred in 53.84% and hyperplasia with atypia occurred in 38.46% individuals. Conclusions: Leiomyoma was the most common etiology contributing towards AUB in the perimenopausal age group. The difference between adenomyosis and leiomyoma may not be easily made clinically as signs and symptoms of adenomyosis and leiomyoma are very similar. Thus, it is important to use histopathological examination as a complementary diagnostic tool in classifying the structural causes of AUB

An outlook on metabolic pathway engineering in crop plants

To produce the essential secondary metabolites, plants are the major and important target source materials for conducting the high-profile metabolic engineering studies. Metabolic pathway engineering of both microorganism targets and plants target contribute towards important drug discovery. In order to efficiently work out in advanced plant metabolic pathway engineering techniques, a detailed knowledge and expertise is essentially needed regarding the plant cell physiology and the mechanics of plant metabolism. Mathematical and statistical models to scale and map the genome for integrative metabolic pathway activity, signal transduction mechanism in the genome, gene regulation and the networks of protein-protein interaction can provide the in-depth knowledge to work efficiently on plant metabolic pathway engineering studies. Incorporation of omics data into these statistical and mathematical models is crucial in the case of drug discovery using the plant system. Recently, artificial intelligence concept and approaches are experimentally applied for efficient and accurate metabolic engineering in plants