Patient Demographics.

<p>Abbreviations: ABI: ankle brachial index; FeDCLIP: female, dialysis, critical limb ischemia, lesion length > 150 mm, poor runoff; LL: lesion length; DCB: drug coated balloon.</p><p>^$ poor runoff was defined as one vessel or none of below-the-knee runoff</p><p>* Calculated by excluding ABI ≥ 1.3</p><p>Patient Demographics.</p

Kaplan-Meier curves for freedom from binary restenosis.

<p>(A) The 12-month binary restenosis-free rate is 77.5% for study participants. (B) A significant difference is noted between Trans-Atlantic Intersociety Consensus (TASC) II B (blue) and TASC C/D (green) lesions in the 12-month binary restenosis-free rate (90% <i>vs</i>. 71%, p = 0.025). (C) No significant differences are observed among the low- (blue), moderate- (gold), and high-risk (green) groups regarding the 12-month binary restenosis-free rates (60%, 84%, and 73%, p = 0.396). (D) The <i>de novo</i> (blue), restenosis (green), and in-stent restenosis (ISR) (gold) lesions have similar 12-month binary restenosis-free rates (79%, 75%, and 80%, p = 0.456).</p

Immediate Procedural Characteristics.

<p>Abbreviation: SFA: superficial femoral artery, RVD: reference vessel diameter, DS: diameter stenosis, MLD: minimal lumen diameter, DCB: drug coated balloon, IVUS: intravascular ultrasound, ISR: in-stent restenosis, MAVE: major adverse vascular event.</p><p>Immediate Procedural Characteristics.</p

Flow chart of study participants.

<p>Flow chart of study participants. FP: femoropopliteal; DCB: drug-coated balloon; EVT: endovascular therapy; MI: myocardial infarction.</p

Multivariate analyses: predictors of binary restenosis and clinically driven target lesion revascularization (CD-TLR).

<p>Abbreviations: CAD: coronary artery disease; CHF: congestive heart failure; CVA: cerebrovascular accident; RC: Rutherford class; LL: lesion length.</p><p>^¶ poor runoff was defined as one vessel or none of below-the-knee runoff</p><p>Multivariate analyses: predictors of binary restenosis and clinically driven target lesion revascularization (CD-TLR).</p

Comparisons of clinical impacts on individuals with Brugada electrocardiographic patterns defined by ISHNE criteria or EHRA/HRS/APHRS criteria: a nationwide community-based study

<p><b>Introduction:</b> Identifying Brugada electrocardiographic pattern (BrP) early is crucial to prevent sudden cardiac death. Two different diagnostic criteria proposed by International Society for Holter and Noninvasive Electrocardiography (ISHNE) and Heart Rhythm Society/European Heart Rhythm Association/Asia-Pacific Heart Rhythm Society (HRS/EHRA/APHRS) were widely used in clinical practice. The difference in prevalence and prognosis of BrP by applying the two different criteria was never studied before.</p> <p><b>Methods:</b> This study was prospectively conducted in a nationwide large-scale stratified random sampling community-based cohort (HALST) from Han Chinese population in Taiwan from December 2008 to December 2012. We compared the prevalence and prognosis of BrP defined by the two diagnostic criteria.</p> <p><b>Results:</b> A total of 5214 adults were enrolled (2530 men) with mean age of 69.3 years. Four had spontaneous type 1 BrP (0.077%). By the HRS/EHRA/APHRS criteria, 68 individuals have type 2 BrP (1.30%) and 101 have type 3 BrP (1.94%) whereas by the ISHNE criteria, 46 individuals exhibited type 2 BrP (0.88%). When applying the ISHNE criteria, the number of individuals with BrP decreased by 71%. However, all-cause mortality and cardiovascular mortality were not different between individuals with or without BrP, irrespective of the criteria used.</p> <p><b>Conclusions:</b> The two different criteria may impact the diagnostic yield of individuals with BrP, but do not affect the prognosis of the individuals with BrP.Key messages</p><p>Comparing with the use of HRS/EHRA/APHRS criteria, the number of individuals with Brugada ECG patterns was decreased by 71% when applying the ISHNE criteria.</p><p>The prognosis of individuals with Brugada ECG patterns defined by 2012 ISHNE or 2013 HRS/EHRA/APHRS criteria were not different.</p><p></p> <p>Comparing with the use of HRS/EHRA/APHRS criteria, the number of individuals with Brugada ECG patterns was decreased by 71% when applying the ISHNE criteria.</p> <p>The prognosis of individuals with Brugada ECG patterns defined by 2012 ISHNE or 2013 HRS/EHRA/APHRS criteria were not different.</p

Comparisons of clinical impacts on individuals with Brugada electrocardiographic patterns defined by ISHNE criteria or EHRA/HRS/APHRS criteria: A nationwide community-based study

[[abstract]]INTRODUCTION: Identifying Brugada electrocardiographic pattern (BrP) early is crucial to prevent sudden cardiac death. Two different diagnostic criteria proposed by International Society for Holter and Noninvasive Electrocardiography (ISHNE) and Heart Rhythm Society/European Heart Rhythm Association/Asia-Pacific Heart Rhythm Society (HRS/EHRA/APHRS) were widely used in clinical practice. The difference in prevalence and prognosis of BrP by applying the two different criteria was never studied before. METHODS: This study was prospectively conducted in a nationwide large-scale stratified random sampling community-based cohort (HALST) from Han Chinese population in Taiwan from December 2008 to December 2012. We compared the prevalence and prognosis of BrP defined by the two diagnostic criteria. RESULTS: A total of 5214 adults were enrolled (2530 men) with mean age of 69.3 years. Four had spontaneous type 1 BrP (0.077%). By the HRS/EHRA/APHRS criteria, 68 individuals have type 2 BrP (1.30%) and 101 have type 3 BrP (1.94%) whereas by the ISHNE criteria, 46 individuals exhibited type 2 BrP (0.88%). When applying the ISHNE criteria, the number of individuals with BrP decreased by 71%. However, all-cause mortality and cardiovascular mortality were not different between individuals with or without BrP, irrespective of the criteria used. CONCLUSIONS: The two different criteria may impact the diagnostic yield of individuals with BrP, but do not affect the prognosis of the individuals with BrP. Key messages Comparing with the use of HRS/EHRA/APHRS criteria, the number of individuals with Brugada ECG patterns was decreased by 71% when applying the ISHNE criteria. The prognosis of individuals with Brugada ECG patterns defined by 2012 ISHNE or 2013 HRS/EHRA/APHRS criteria were not different