Additional file 1: of The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD

Detailed Method description. (PDF 118 kb

Additional file 4: of The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD

Table E1. Correlations between serum and sputum IL-33 and sST2, ST2 mRNA and clinical parameters in COPD. FEV1 – forced expiratory volume in first second; FVC – forced vital capacity; CAT – COPD assessment test; 6MWT – six-minute walk test; mMRC – modified Medical Research Council dyspnea scale. (PDF 39 kb

Additional file 5: of The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD

Figure E2. Circulating (A) and sputum (B) hemopoietic progenitor cells (HPC) in patients with and without sputum eosinophilia. **p < 0.01. (PDF 56 kb

Additional file 2: of The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD

Figure E4. Hemopoietic progenitor cells gating strategy. (PDF 88 kb

Histopathological verifications of NSCLC tissue samples.

<p>*AJCC – American Joint Committee on Cancer Staging according to the IASCLC Staging Project 7th ed. (2010) Cancer.</p><p>*pTNM — post-operative Tumor Node Metastasis classification according to the WHO Histological Typing of Lung Tumor.</p

Box-and-whisker plots, representing <i>STAT5B</i> expression levels (mean RQ values) in the studied tumor groups classified according to pTNM staging in relation to their size.

<p>Box-and-whisker plots, representing <i>STAT5B</i> expression levels (mean RQ values) in the studied tumor groups classified according to pTNM staging in relation to their size.</p

Box-and-whisker plots, representing <i>PIAS3</i> expression levels (mean RQ values) in the studied tumor groups classified according to the histopathological NSCLC subtypes.

<p>Box-and-whisker plots, representing <i>PIAS3</i> expression levels (mean RQ values) in the studied tumor groups classified according to the histopathological NSCLC subtypes.</p

The results of Neuman-Keuls' multiple comparison test regarding differences in <i>STAT5B</i> RQ values in the studied tumor groups classified according to pTNM staging in relation to the tumor size.

<p>The results of Neuman-Keuls' multiple comparison test regarding differences in <i>STAT5B</i> RQ values in the studied tumor groups classified according to pTNM staging in relation to the tumor size.</p

Positive correlation between STAT5B protein levels (ng/ml) and gene expression levels (RQ values) in NSCLC samples.

<p>Positive correlation between STAT5B protein levels (ng/ml) and gene expression levels (RQ values) in NSCLC samples.</p

Box-and-whisker plots, representing STAT5B protein levels (ng/ml) in the studied tumor groups classified according to pTNM staging in relation to the tumor size.

<p>Box-and-whisker plots, representing STAT5B protein levels (ng/ml) in the studied tumor groups classified according to pTNM staging in relation to the tumor size.</p