505 research outputs found
Large-D Expansion from Variational Perturbation Theory
We derive recursively the perturbation series for the ground-state energy of
the D-dimensional anharmonic oscillator and resum it using variational
perturbation theory (VPT). From the exponentially fast converging approximants,
we extract the coefficients of the large-D expansion to higher orders. The
calculation effort is much smaller than in the standard field-theoretic
approach based on the Hubbard-Stratonovich transformation.Comment: Author Information under http://hbar.wustl.edu/~sbrandt and
http://www.theo-phys.uni-essen.de/tp/ags/pelster_di
Pressure of massless hot scalar theory in the boundary effective theory framework
We use the boundary effective theory (BET) approach to thermal field theory
in order to calculate the pressure of a system of massless scalar fields with
quartic interaction. The method naturally separates the infrared physics, and
is essentially non-perturbative. To lowest order, the main ingredient is the
solution of the free Euler-Lagrange equation with non-trivial (time) boundary
conditions. We derive a resummed pressure, which is in good agreement with
recent calculations found in the literature, following a very direct and
compact procedure.Comment: 10 pages, 4 figure
Global Anomalies in the Batalin Vilkovisky Quantization
The Batalin Vilkovisky (BV) quantization provides a general procedure for
calculating anomalies associated to gauge symmetries. Recent results show that
even higher loop order contributions can be calculated by introducing an
appropriate regularization-renormalization scheme. However, in its standard
form, the BV quantization is not sensible to quantum violations of the
classical conservation of Noether currents, the so called global anomalies. We
show here that the BV field antifield method can be extended in such a way that
the Ward identities involving divergencies of global Abelian currents can be
calculated from the generating functional, a result that would not be obtained
by just associating constant ghosts to global symmetries. This extension,
consisting of trivially gauging the global Abelian symmetries, poses no extra
obstruction to the solution of the master equation, as it happens in the case
of gauge anomalies. We illustrate the procedure with the axial model and also
calculating the Adler Bell Jackiw anomaly.Comment: We emphasized the fact that our procedure only works for the case of
Abelian global anomalies. Section 3 was rewritten and some references were
added. 12 pages, LATEX. Revised version that will appear in Phys. Rev.
Error estimation and reduction with cross correlations
Besides the well-known effect of autocorrelations in time series of Monte
Carlo simulation data resulting from the underlying Markov process, using the
same data pool for computing various estimates entails additional cross
correlations. This effect, if not properly taken into account, leads to
systematically wrong error estimates for combined quantities. Using a
straightforward recipe of data analysis employing the jackknife or similar
resampling techniques, such problems can be avoided. In addition, a covariance
analysis allows for the formulation of optimal estimators with often
significantly reduced variance as compared to more conventional averages.Comment: 16 pages, RevTEX4, 4 figures, 6 tables, published versio
A Superspace Formulation for the Master Equation
It is shown that the quantum master equation of the Field Antifield
quantization method at one loop order can be translated into the requirement of
a superfield structure for the action. The Pauli Villars regularization is
implemented in this BRST superspace and the case of anomalous gauge theories is
investigated. The quantum action, including Wess Zumino terms, shows up as one
of the components of a superfield that includes the BRST anomalies in the other
component. The example of W2 quantum gravity is also discussed.Comment: The constrained nature of standard BRST superfields and the
importance of using Alfaro and Damgaard's collective fields in the superspace
approach to avoid undefined superfield derivatives was emphasized. To appear
in Phys. Rev. D. Latex file, 20 page
A guide for managing patients with stage I NSCLC: Deciding between lobectomy, segmentectomy, wedge, SBRT and ablation-part 2: Systematic review of evidence regarding resection extent in generally healthy patients
Background: Clinical decision-making for patients with stage I lung cancer is complex. It involves multiple options (lobectomy, segmentectomy, wedge, stereotactic body radiotherapy, thermal ablation), weighing multiple outcomes (e.g., short-, intermediate-, long-term) and multiple aspects of each (e.g., magnitude of a difference, the degree of confidence in the evidence, and the applicability to the patient and setting at hand). A structure is needed to summarize the relevant evidence for an individual patient and to identify which outcomes have the greatest impact on the decision-making.
Methods: A PubMed systematic review from 2000-2021 of outcomes after lobectomy, segmentectomy and wedge resection in generally healthy patients is the focus of this paper. Evidence was abstracted from randomized trials and non-randomized comparisons with at least some adjustment for confounders. The analysis involved careful assessment, including characteristics of patients, settings, residual confounding etc. to expose degrees of uncertainty and applicability to individual patients. Evidence is summarized that provides an at-a-glance overall impression as well as the ability to delve into layers of details of the patients, settings and treatments involved.
Results: In healthy patients there is no short-term benefit to sublobar resection
Conclusions: A systematic, comprehensive summary of evidence regarding resection extent in healthy patients with attention to aspects of applicability, uncertainty and effect modifiers provides a foundation on which to build a framework for individualized clinical decision-making
A guide for managing patients with stage I NSCLC: Deciding between lobectomy, segmentectomy, wedge, SBRT and ablation-part 3: Systematic review of evidence regarding surgery in compromised patients or specific tumors
Background: Clinical decision-making for patients with stage I lung cancer is complex. It involves multiple options [lobectomy, segmentectomy, wedge, stereotactic body radiotherapy (SBRT), thermal ablation], weighing multiple outcomes (e.g., short-, intermediate-, long-term) and multiple aspects of each (e.g., magnitude of a difference, the degree of confidence in the evidence, and the applicability to the patient and setting at hand). A structure is needed to summarize the relevant evidence for an individual patient and to identify which outcomes have the greatest impact on the decision-making.
Methods: A PubMed systematic review from 2000-2021 of outcomes after lobectomy, segmentectomy and wedge resection in older patients, patients with limited pulmonary reserve and favorable tumors is the focus of this paper. Evidence was abstracted from randomized trials and non-randomized comparisons (NRCs) with adjustment for confounders. The analysis involved careful assessment, including characteristics of patients, settings, residual confounding etc. to expose degrees of uncertainty and applicability to individual patients. Evidence is summarized that provides an at-a-glance overall impression as well as the ability to delve into layers of details of the patients, settings and treatments involved.
Results: In older patients, perioperative mortality is minimally altered by resection extent and only slightly affected by increasing age; sublobar resection may slightly decrease morbidity. Long-term outcomes are worse after lesser resection; the difference is slightly attenuated with increasing age. Reported short-term outcomes are quite acceptable in (selected) patients with severely limited pulmonary reserve, not clearly altered by resection extent but substantially improved by a minimally invasive approach. Quality-of-life (QOL) and impact on pulmonary function hasn\u27t been well studied, but there appears to be little difference by resection extent in older or compromised patients. Patient selection is paramount but not well defined. Ground-glass and screen-detected tumors exhibit favorable long-term outcomes regardless of resection extent; however solid tumors \u3c1 cm are not a reliably favorable group.
Conclusions: A systematic, comprehensive summary of evidence regarding resection extent in compromised patients and favorable tumors with attention to aspects of applicability, uncertainty and effect modifiers provides a foundation for a framework for individualized decision-making
A guide for managing patients with stage I NSCLC: Deciding between lobectomy, segmentectomy, wedge, SBRT and ablation-part 4: Systematic review of evidence involving SBRT and ablation
Background: Clinical decision-making for patients with stage I lung cancer is complex. It involves multiple options [lobectomy, segmentectomy, wedge, stereotactic body radiotherapy (SBRT), thermal ablation], weighing multiple outcomes (e.g., short-, intermediate-, long-term) and multiple aspects of each (e.g., magnitude of a difference, the degree of confidence in the evidence, and the applicability to the patient and setting at hand). A structure is needed to summarize the relevant evidence for an individual patient and to identify which outcomes have the greatest impact on the decision-making.
Methods: A PubMed systematic review from 2000-2021 of outcomes after SBRT or thermal ablation
Results: Short-term outcomes are meaningfully better after SBRT than resection. SBRT doesn\u27t affect quality-of-life (QOL), on average pulmonary function is not altered, but a minority of patients may experience gradual late toxicity. Adjusted non-randomized comparisons demonstrate a clinically relevant detriment in long-term outcomes after SBRT
Conclusions: A systematic, comprehensive summary of evidence regarding Stereotactic Body Radiotherapy or thermal ablatio
Scaling critical behavior of superconductors at zero magnetic field
We consider the scaling behavior in the critical domain of superconductors at
zero external magnetic field. The first part of the paper is concerned with the
Ginzburg-Landau model in the zero magnetic field Meissner phase. We discuss the
scaling behavior of the superfluid density and we give an alternative proof of
Josephson's relation for a charged superfluid. This proof is obtained as a
consequence of an exact renormalization group equation for the photon mass. We
obtain Josephson's relation directly in the form , that
is, we do not need to assume that the hyperscaling relation holds. Next, we
give an interpretation of a recent experiment performed in thin films of
. We argue that the measured mean field like
behavior of the penetration depth exponent is possibly associated with a
non-trivial critical behavior and we predict the exponents and
for the correlation lenght and specific heat, respectively. In the
second part of the paper we discuss the scaling behavior in the continuum dual
Ginzburg-Landau model. After reviewing lattice duality in the Ginzburg-Landau
model, we discuss the continuum dual version by considering a family of
scalings characterized by a parameter introduced such that
, where is the bare mass of the magnetic
induction field. We discuss the difficulties in identifying the renormalized
magnetic induction mass with the photon mass. We show that the only way to have
a critical regime with is having , that
is, with having the scaling behavior of the renormalized photon mass.Comment: RevTex, 15 pages, no figures; the subsection III-C has been removed
due to a mistak
First trimester elevation in circulating endothelin-1 and arterial stiffness are predictive of late pregnancy preeclampsia
Preeclampsia (PE) is characterized by late pregnancy hypertension and proteinuria. PE causes significant morbidity for the maternal-fetal unit. Circulating endothelin-1 (ET-1), a potent vasoconstrictor, is elevated at the time of diagnosis of human PE. In addition, women with PE demonstrate arterial stiffness as early as the end of the first trimester. However, it is unknown if arterial stiffness is associated with a first trimester elevation in ET-1 and post-delivery placental ET-1. We hypothesized that 1) first trimester plasma ET-1 is elevated and is associated with arterial stiffness in women who develop PE; 2) first trimester ET-1 is predictive of PE; and 3) placental ET-1 is increased in PE. To address these questions, we performed a nested case-control study in women at risk for P
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