How Can the European Federation for Colposcopy Promote High Quality Colposcopy Throughout Europe?

Since its inception in 1998, the European Federation for Colposcopy (EFC) now comprises 26 member societies. Its principle aim is to promote high quality colposcopy throughout Europe with special emphasis on training, education and treatment. This review summarises EFC’s activities and achievements to date

Clinical data.

*<p>P<0.001 vs normal pregnancy.</p>**<p>P<0.001 vs normal pregnancy, gestational diabetes and gestational hypertension.</p>***<p>P<0.001 vs normal pregnancy, gestational hypertension and preeclampsia.</p

Comparison of telomere length between male and female infants.

<p>Telomere length was not significantly different between male and female fetuses of women with normal pregnancy (NP) (P = 0.587), gestational diabetes (GDM) (P = 0.746), gestational hypertension (GH) (P = 0.772) or preeclampsia (PE) (P = 0.107).</p

Comparison of fetal telomere length among normal pregnancy (NP), gestational diabetes (GDM), gestational hypertension (GH) and preeclampsia (PE).

<p>There were significant differences in fetal telomere length (F = 3.083, P = 0.028). Fetal telomere length was significantly shorter in gestational diabetes than that of normal pregnancy (P = 0.028). There was no significant differences in fetal telomere length between normal pregnancy and gestational hypertension (P = 0.561), between normal pregnancy and preeclampsia (P = 0.841).</p

Regional plots of the two loci associated with telomere length.

<p>Results are shown for the 12q13.13 (a) and 5p15.33 (b) regions. Top, −log₁₀<i>P</i> values are shown for SNPs for the region 350 kb on either side of the marker SNPs. <i>P</i>_GWAS is for results obtained from the discovery stage and is shown for genotyped (circle). <i>P</i>_{GWAS-Rep1-Rep2} is for results obtained from the combination of the initial and replication study data (diamond). The marker SNP is shown in purple, and the <i>r</i>² values of the other SNPs are indicated by color. The genes within the relevant regions are annotated and shown as arrows.</p

Z-score based meta-analysis results for GWAS and replication studies for two leading SNPs on 5p15.33 and 12q13.13.

<p>Note: In each panel, markers (SNP) are given along with chromosomal (CHR) and base pair (BP) positions.</p><p>A1, minor allele. SE, standard error. Beta coefficients based on z-scores.</p><p><i>P</i>het: p-values for the heterogeneity test.</p