StyleGAN3: Generative Networks for Improving the Equivariance of Translation and Rotation

StyleGAN can use style to affect facial posture and identity features, and noise to affect hair, wrinkles, skin color and other details. Among these, the outcomes of the picture processing will vary slightly between different versions of styleGAN. As a result, the comparison of performance differences between styleGAN2 and the two modified versions of styleGAN3 will be the main focus of this study. We used the FFHQ dataset as the dataset and FID, EQ-T, and EQ-R were used to be the assessment of the model. In the end, we discovered that Stylegan3 version is a better generative network to improve the equivariance. Our findings have a positive impact on the creation of animation and videos

The Development of NBA in China: A Glocalization Perspective

The growing sport industry and 1.3 billion potential consumers in China have been garnering tremendous attention from more and more overseas professional sport leagues. Comparatively, the National Basketball Association (NBA) has had remarkable success in the Chinese market. From the perspective of sport competition or marketing operations, the NBA’s achievement in China provides a model for other overseas sport leagues. This case study was organized by summarizing the developmental history of NBA in China, analyzing its current promotional practices, investigating into its marketing strategies, and extrapolating practical references for other sport leagues aiming to penetrating into the Chinese marketplace. In the perspective of glocalization, multinational corporations should combine both standardized and adapted elements to conceptualize globally and act locally (Tanahashi, 2008). By taking this approach, marketers can meet the needs of local consumers effectively while still maintaining some extent of global standardization (Singh, Kumar, & Baack, 2005). To obtain in-depth understanding about NBA globalization and localization in China, we conducted one-on-one interviews with Chinese academic scholars in sport management and practitioners in Chinese basketball industry and NBA China. Two focus groups with six participants in each group were conducted to learn the perception of NBA products from the perspective of Chinese consumer. The qualitative data analysis was organized around four major aspects: products, media, management and public relations, which were highlighted in the glocalization of transnational corporations (Yang, 2003; Zhang, 2007) The current case study concluded that although NBA has achieved huge successes in the areas of building a large fan base, increasing media exposure, and garnering net income after its entry to China, it still faces many challenges. One viable solution for the NBA is to bring authentic American cultural commodities while adding Chinese characteristics to accommodate local fans. Combining global heroes such as Michael Jordan and Kobe Bryant and local hero such as Yao Ming, Yi Jianlian, and Jeremy Lin, NBA games will continue to appeal to millions of Chinese fans. Meantime, NBA management needs to continue seeking ways to work out and through the differences in government models and cultural contexts between China and United States. Some viable actions include the promotion of Chinese youth basketball, the training service for elite basketball players, and government-level public relations. In addition, this study suggested that the research framework of glocalization would be an ever intriguing inquiry needed for other sport organizations or leagues seeking expansion to overseas markets

Rate-Distortion Optimized Post-Training Quantization for Learned Image Compression

Quantizing floating-point neural network to its fixed-point representation is crucial for Learned Image Compression (LIC) because it ensures the decoding consistency for interoperability and reduces space-time complexity for implementation. Existing solutions often have to retrain the network for model quantization which is time consuming and impractical. This work suggests the use of Post-Training Quantization (PTQ) to directly process pretrained, off-the-shelf LIC models. We theoretically prove that minimizing the mean squared error (MSE) in PTQ is sub-optimal for compression task and thus develop a novel Rate-Distortion (R-D) Optimized PTQ (RDO-PTQ) to best retain the compression performance. Such RDO-PTQ just needs to compress few images (e.g., 10) to optimize the transformation of weight, bias, and activation of underlying LIC model from its native 32-bit floating-point (FP32) format to 8-bit fixed-point (INT8) precision for fixed-point inference onwards. Experiments reveal outstanding efficiency of the proposed method on different LICs, showing the closest coding performance to their floating-point counterparts. And, our method is a lightweight and plug-and-play approach without any need of model retraining which is attractive to practitioners

Dynamic evolution of ceftazidime–avibactam resistance due to interchanges between blaKPC-2 and blaKPC-145 during treatment of Klebsiella pneumoniae infection

BackgroundThe emergence of ceftazidime–avibactam (CZA) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is of major concern due to limited therapeutic options.MethodsIn this study, 10 CRKP strains were isolated from different samples of a patient with CRKP infection receiving CZA treatment. Whole-genome sequencing (WGS) and conjugation experiments were performed to determine the transferability of the carbapenem resistance gene.ResultsThis infection began with a KPC-2-producing K. pneumoniae (CZA MIC = 2 μg/mL, imipenem MIC ≥ 16 μg/mL). After 20 days of CZA treatment, the strains switched to the amino acid substitution of T263A caused by a novel KPC-producing gene, blaKPC-145, which restored carbapenem susceptibility but showed CZA resistance (CZA MIC ≥ 256 μg/mL, imipenem MIC = 1 μg/mL). The blaKPC-145 gene was located on a 148,185-bp untransformable IncFII-type plasmid. The subsequent use of carbapenem against KPC-145-producing K. pneumoniae infection led to a reversion of KPC-2 production (CZA MIC = 2 μg/mL, imipenem MIC ≥ 16 μg/mL). WGS analysis showed that all isolates belonged to ST11-KL47, and the number of SNPs was 14. This implied that these blaKPC-positive K. pneumoniae isolates might originate from a single clone and have been colonized for a long time during the 120-day treatment period.ConclusionThis is the first report of CZA resistance caused by blaKPC-145, which emerged during the treatment with CZA against blaKPC-2-positive K. pneumoniae-associated infection in China. These findings indicated that routine testing for antibiotic susceptibility and carbapenemase genotype is essential during CZA treatment

IL28B is associated with outcomes of chronic HBV infection

Purpose The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes. Materials and Methods IL28B genetic variations (rs12979860) were genotyped by pyrosequencing of DNA samples from 137 individuals with chronic HBV infection [50 inactive carriers (IC), 34 chronic hepatitis B (CHB), 27 cirrhosis, 26 hepatocellular carcinoma (HCC)], and 19 healthy controls. IL28A/B mRNA expression in peripheral blood mononuclear cells was determined by qRT-PCR, and serum IL28B protein was measured by ELISA. Results Patients with IL28B C/C genotype had greater IL28A/B mRNA expression and higher IL28B protein levels than C/T patients. Within the various disease stages, compared to IC and healthy controls, IL28B expression was reduced in the CHB, cirrhosis, and HCC cohorts (CHB vs. IC, p=0.02; cirrhosis vs. IC, p=0.01; HCC vs. IC, p=0.001; CHB vs. controls, p&#60;0.01; cirrhosis vs. controls, p&#60;0.01; HCC vs. controls, p&#60;0.01). When stratified with respect to serum HBV markers in the IC and CHB cohorts, IL28B mRNA and protein levels were higher in HBeAg-positive than negative individuals (p=0.01). Logistic regression analysis revealed that factors associated with high IL28B protein levels were C/C versus C/T genotype [p=0.016, odds ratio (OR)=0.25, 95% confidence interval (CI)=0.08-0.78], high alanine aminotransferase values (p&#60;0.001, OR=8.02, 95% CI=2.64-24.4), and the IC stage of HBV infection (p&#60;0.001). Conclusion Our data suggest that IL28B genetic variations may play an important role in long-term development of disease in chronic HBV infections.</p