Method Of Real-Time Assessing Of Life Of Hp Heater Tube-Plate In Power Plants

AbstractIn large power plants, in order to improve safety and stability of HP heaters(High Pressure) in operation, thicker tubeplates are designed and made, which will lead to more thermal stress between tube-plate and end-cover, furthermore, will reduce the thermal fatigue life of HP heaters sharply. so it is necessary to monitor the thermal fatigue its life. However, at presently a large portion of methods carry on calculating or analyzing beforehand or afterwords, which make effect of analyzing life being less greatly. In this paper, according to the theory of calculation of thermal fatigue life, real-time gathering tube-plate's temperatures, and computing the life everyday, provide the basis of operating and maintaining in the power plate

Optimization of the thermal environment of a small-scale data center in China

In data centers, a large number of IT sever racks with different heat dissipation rates are arranged in multiple rows, leading to much higher per-unit heat release and therefore more uneven temperature distribution than in general buildings. This paper chooses a small-scale data center located in China to analyze the thermal environment for the operation of these critical equipments. The wind speed and temperature in the data center were measured, and a corresponding computer room model was established via computational fluid dynamics (CFD) simulation software. Based on it, the characteristics of flow field and temperature field of the data center were analyzed. The optimization methods for problem of uneven temperature distribution and chaotic air supply in the data center were proposed and verified by evaluation index. Furthermore, the return temperature index(RHI) increased from 0.918 to 0.93, the return heat index(RTI) reduced from 0.222 to 0.342

Xylan-Based Hydrogels as a Potential Carrier for Drug Delivery: Effect of Pore-Forming Agents

Pore-forming agents have a significant influence on the pore structure of hydrogels. In this study, a porogenic technique was employed to investigate the preparation of macroporous hydrogels which were synthesized by radical copolymerization of carboxymethyl xylan with acrylamide and N-isopropylacrylamide under the function of a cross-linking agent. Six kinds of pore-forming agents were used: polyvinylpyrrolidone K30, polyethylene glycol 2000, carbamide, NaCl, CaCO3, and NaHCO3. The application of these hydrogels is also discussed. The results show that pore-forming agents had an important impact on the pore structure of the hydrogels and consequently affected properties of the hydrogels such as swelling ratio and mechanical strength, while little effect was noted on the thermal property of the hydrogels. 5-Fluorouracil was used as a model drug to study the drug release of the as-prepared hydrogels, and it was found that the drug release was substantially improved after using the NaHCO3 pore-forming agent: a cumulative release rate of up to 71.05% was achieved

Peptide transporter 1 (PepT1) in fish: A review

The Peptide Transporter 1 (PepT1) plays an important role in animal protein nutrition. This is a low-affinity/high-capacity, stereoselective transmembrane transporter that mediates the uptake of a fraction of dietary amino acids in their di- and tripeptide forms. PepT1 is highly expressed in the intestines of vertebrates and the current studies examining PepT1 function have concentrated mostly on mammals and less emphasis has been placed on protein nutrition in fish. In the gastrointestinal track, amino acids are absorbed more efficiently in the form of small peptides than as free amino acids suggesting a potential role of PepT1 in the optimization of amino acid absorption which is relevant for fish nutrition. Therefore, this review focused on the physiological characteristics, structures, tissue distribution and expression of PepT1 transcripts and regulation of PepT1 protein in fish

Adsorption Kinetics and Thermodynamics of Cellulose Dinitrobenzoate Prepared in Ionic Liquid for the Removal Of Creatinine

Creatinine is one of the major toxins in patients suffering from chronic renal failure. In this paper, cellulose dinitrobenzoate, with a degree of substitution (DS) of 0.15, was used as an oral adsorbent for creatinine adsorption. Cellulose dinitrobenzoate was prepared by modification of cellulose with 3,5-dinitrobenzoyl chloride in 1-butyl-3-methylimidazolium chloride (BMIMCl) ionic liquid as a homogenous medium. The effects of contact time, pH, adsorption temperature, and initial concentration of creatinine on the adsorption per unit mass of cellulose dinitrobenzoate were studied, comparatively. Results showed that the maximum adsorption per unit mass for creatinine was 3.88 mg/g. Furthermore, the adsorption process was spontaneous and exothermic. It was determined that the experimental results were well fitted to the pseudo-second-order rate equation and the Freundlich adsorption isotherm. Compared with traditional oral adsorbents, this cellulose-based adsorbent was biocompatible and could remove creatinine from dialysate effectively

pH-Sensitive Ratiometric Fluorescent Probe for Evaluation of Tumor Treatments

Determining therapeutic efficacy is critical for tumor precision theranostics. In order to monitor the efficacy of anti-cancer drugs (e.g., Paclitaxel), a pH-sensitive ratiometric fluorescent imaging probe was constructed. The pH-sensitive ratiometric fluorescent dye ANNA was covalently coupled to the N-terminal of the cell-penetrating TAT peptide through an amidation reaction (TAT-ANNA). The in vitro cellular experiments determined that the TAT-ANNA probe could penetrate the cell membrane and image the intracellular pH in real time. The in vivo experiments were then carried out, and the ratiometric pH response to the state of the tumor was recorded immediately after medication. The TAT-ANNA probe was successfully used to monitor the pharmacodynamics of anti-cancer drugs in vivo

B cells were related to HBsAg seroconversion in inactive HBsAg carriers following peginterferon therapy.

Our recent study showed high rate of HBsAg seroconversion achieved in inactive HBsAg carriers (IHCs) treated with peginterferon (PEG-IFN). To better understand the immune-mediated component to the HBsAg seroconversion, we investigated the role of B cells in this study. A total of 44 IHCs were given 48 weeks of PEG-IFN. Fifteen cases achieve HBsAg seroconversion (R group), whereas 29 failed (NR group). The proportion of total B cells and plasma B cells were measured before and during treatment. We found that the proportion of total B cells and plasma B cells was no significant between R group and NR group at baseline, but significantly higher in R group than NR group during PEG-IFN treatment, even when the exact age-, sex-, and treatment period-match was made. In conclusion, we demonstrated the increase of total B cell and plasma B cells during PEG-IFN treatment favored HBsAg seroconversion for IHC, and B cells may play a role in HBV seroconversion