Analysis and Prediction of “AI + Education” Attention Based on Baidu Index—Taking Guizhou Province as an Example

Studying the attention of “artificial intelligence + education” in ethnic areas is of great significance for China for promoting the integrated development of new educational modes and modern technology in the western region. Guizhou province is an area inhabited by ethnic minorities, located in the heart of Southwest China. The development of its intelligent education has strong enlightenment for the whole country and the region. Therefore, this paper selects the Baidu Index of “artificial intelligence (AI) + education” in Guizhou province from 2013 to 2020, analyzes the spatial–temporal characteristics of its network attention by using the elastic coefficient method, and builds the ARIMA model on this basis to predict future development. The results show that the public’s attention to “AI + education” differs significantly in time and space. Then, according to the prediction results, this paper puts forward relevant suggestions for the country to promote the sustainable development of education in western ethnic areas

Role of Nampt and Visceral Adiposity in Esophagogastric Junction Adenocarcinoma

Nampt including eNampt and iNampt may contribute to mediating obesity-associated cancers. This study investigated the role of Nampt in esophagogastric junction adenocarcinoma (EGA), a cancer strongly correlated with obesity. Visceral adiposity was defined by waist circumference or VFA. eNampt in sera were measured by enzyme-linked immunosorbent assay. iNampt expression in EGA was determined by PCR, western blot, and immunohistochemistry. Sera eNampt were significantly elevated in these overweight and obese patients, especially for viscerally obese patients, and positively correlated with BMI, waist circumference, VFA, and also primary tumor, regional lymph nodes, and TNM stage (P<0.05). iNampt expression in both the mRNA and protein levels was upregulated in EGAs (P<0.05). iNampt staining was found primarily in the cytoplasm and nuclei and significantly associated with tumor, lymph nodes, and TNM stage and also correlated positively with serum eNampt, BMI, total fat area, VFA, superficial fat area, and waist circumference (P<0.05). iNampt, eNampt, tumor, lymph nodes, and TNM stage correlated to the survival of EGAs, and iNampt expression and TNM stage affected the prognosis independently (P<0.05). This study highlighted the association of eNampt/iNampt with visceral obesity and a potential impact on the biology of EGA

Essays on river mechanics

CER95-96-PYJ-2.Presented by the Graduate Students in CE 717 River Mechanics (Spring, 1996).Includes bibliographical references.April 1996

The Impacts and Origins of A-site Instability in Formamidinium-Cesium Lead Iodide Perovskite Solar Cells Under Extended Operation

Improved understanding of the origins of instability during photovoltaic operation of perovskite solar cell materials must be established to overcome barriers to commercialization. In this study, we analyze the microscopic mechanisms of degradation in high-performing methylammonium free (FA0.9Cs0.1PbI3) perovskite solar cells (PSC) over 600 hours of operation under stressors inherent to PV operation, including heat, illumination, and a load while excluding atmospheric effects by testing in a water-and oxygen-free atmosphere. While the PSCs exhibit reasonable thermal stability, they show considerable performance loss under constant illumination or stable power output. Synchrotron-based nanoprobe X-ray fluorescence and X-ray beam induced current (XRF/XBIC) measurements reveal segregation of current-blocking Cs-rich phases during stress testing. The decrease in performance correlates with the resulting number density of the Cs-rich clusters, which varies by stress condition. These findings unveil cation-dependent instability in FA0.9Cs0.1PbI3 perovskites and provide a framework for understanding the energy landscape in alloy perovskites to guide the engineering of long-lived halide perovskite devices

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

How environmental cues regulate adult stem cell and cancer cell activity through surface receptors is poorly understood. Angiopoietin-like proteins (ANGPTLs), a family of seven secreted glycoproteins, are known to support the activity of haematopoietic stem cells (HSCs) in vitro and in vivo. ANGPTLs also have important roles in lipid metabolism, angiogenesis and inflammation, but were considered 'orphan ligands' because no receptors were identified. Here we show that the immune-inhibitory receptor human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse orthologue paired immunoglobulin-like receptor (PIRB) are receptors for several ANGPTLs. LILRB2 and PIRB are expressed on human and mouse HSCs, respectively, and the binding of ANGPTLs to these receptors supported ex vivo expansion of HSCs. In mouse transplantation acute myeloid leukaemia models, a deficiency in intracellular signalling of PIRB resulted in increased differentiation of leukaemia cells, revealing that PIRB supports leukaemia development. Our study indicates an unexpected functional significance of classical immune-inhibitory receptors in maintenance of stemness of normal adult stem cells and in support of cancer development.</p