1,316 research outputs found

    Eine Untersuchung zur Textkohärenz in Zeitungsartikeln und Märchen

    Full text link
    Die Untersuchung bezweckt, die Fähigkeiten deutschlernender Koreaner beim Verstehen und Schreiben deutschsprachiger Texte zu verbessern und zu fördern. Die Ergebnisse sprachlicher Reflexionen und Übungen im Deutschunterricht sollten nicht Selbstzweck bleiben, sondern in der sprachlichen Alltagspraxis ihre Anwendung erfahren

    Development of Indexes for the Performance Evaluation of e-SCM

    Get PDF
    Web-based sharing of information across the supply chain can bring a host of advantages to the trading partners. lower cost, leaner inventories, and more efficient shipping are just the beginning. eSCM is technology-enabled ability to concurrently manage high levels of complexity and multiple external relationships. This study presents that the development of indexes for the performance evaluation of e-SCM should be given more priority by companies giving weights to each index. Deductive research is used for the development of evaluation items and AHP method for the development of weights of the items. According to priority of each category - relationship between supplier and company, relationship between partner and company and relationship between customer and company- is as follows; Company driven type: relationship between customer and company, relationship between supplier and company, relationship between partner and company. Market portal type: relationship between supplier and company, relationship between customer and company, relationship between partner and company

    The Dendritic magnetic avalanches in carbon-free MgB2_2 thin films with and without a deposited Au layer

    Full text link
    From the magneto optics images (MOI), the dendritic magnetic avalanche is known to appear dominantly for thin films of the newly discovered MgB2_2. To clarify the origin of this phenomenon, we studied in detail the MOI of carbon-free MgB2_2 thin films with and without a deposited gold layer. The MOI indicated carbon contamination was not the main source of the avalanche. The MOI clearly showed that the deposition of metallic gold deposition on top of a MgB2_2 thin film improved its thermal stability and suppressed the sudden appearance of the dendritic flux avalanche. This is consistent with the previous observation of flux noise in the magnetization.Comment: 9 pages, 4 figeure

    NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor β1 production

    Get PDF
    Although NKT cells has been known to exert protective roles in the development of autoimmune diseases, the functional roles of NKT cells in the downstream events of antibody-induced joint inflammation remain unknown. Thus, we explored the functional roles of NKT cells in antibody-induced arthritis using the K/BxN serum transfer model. NKT cell–deficient mice were resistant to the development of arthritis, and wild-type mice administrated with α-galactosyl ceramide, a potent NKT cell activator, aggravated arthritis. In CD1d−/− mice, transforming growth factor (TGF)-β1 was found to be elevated in joint tissues, and the blockade of TGF-β1 using neutralizing monoclonal antibodies restored arthritis. The administration of recombinant TGF-β1 into C57BL/6 mice reduced joint inflammation. Moreover, the adoptive transfer of NKT cells into CD1d−/− mice restored arthritis and reduced TGF-β1 production. In vitro assay demonstrated that interleukin (IL)-4 and interferon (IFN)-γ were involved in suppressing TGF-β1 production in joint cells. The adoptive transfer of NKT cells from IL-4−/− or IFN-γ−/− mice did not reverse arthritis and TGF-β1 production in CD1d−/− mice. In conclusion, NKT cells producing IL-4 and IFN-γ play a role in immune complex–induced joint inflammation by regulating TGF-β1

    Dietary Intake and Serum Levels of Iron in Relation to Oxidative Stress in Breast Cancer Patients

    Get PDF
    Iron may induce oxidative stress via production of reactive oxygen species, facilitating mammary carcinogenesis. This study investigated the role of iron in relation to oxidative stress as a potential risk factor in the development of breast cancer (BC). BC patients (n = 121) and healthy age-matched controls (n = 149) were entered into the study. Iron and antioxidant vitamins intakes were estimated using a quantitative food frequency questionnaire. Thirty one subjects from each group provided blood samples for measurement of serum iron, plasma malondialdehyde (MDA) and ferric reducing ability of plasma (FRAP). Total and non-heme iron intake of BC patients were lower than those of the controls. However, the serum iron level was significantly higher in BC patients. Plasma MDA levels were also significantly higher in BC patients whereas no significant difference in FRAP values were observed between the two groups. Log-transformed serum iron concentration showed no significant correlation with MDA or FRAP. These results suggest that serum iron overload may be a breast cancer risk factor possibly due to increased oxidative stress

    Flux Dendrites of Opposite Polarity in Superconducting MgB2_2 rings observed with magneto-optical imaging

    Full text link
    Magneto-optical imaging was used to observe flux dendrites with opposite polarities simultaneously penetrate superconducting, ring-shaped MgB2_2 films. By applying a perpendicular magnetic field, branching dendritic structures nucleate at the outer edge and abruptly propagate deep into the rings. When these structures reach close to the inner edge, where flux with opposite polarity has penetrated the superconductor, they occasionally trigger anti-flux dendrites. These anti-dendrites do not branch, but instead trace the triggering dendrite in the backward direction. Two trigger mechanisms, a non-local magnetic and a local thermal, are considered as possible explanations for this unexpected behaviour. Increasing the applied field further, the rings are perforated by dendrites which carry flux to the center hole. Repeated perforations lead to a reversed field profile and new features of dendrite activity when the applied field is subsequently reduced.Comment: 6 pages, 6 figures, accepted to Phys. Rev.

    Two-gap and paramagnetic pair-breaking effects on upper critical field of SmFeAsO0.85_{0.85} and SmFeAsO0.8_{0.8}F0.2_{0.2} single crystals

    Full text link
    We investigated the temperature dependence of the upper critical field [Hc2(T)H_{c2}(T)] of fluorine-free SmFeAsO0.85_{0.85} and fluorine-doped SmFeAsO0.8_{0.8}F0.2_{0.2} single crystals by measuring the resistive transition in low static magnetic fields and in pulsed fields up to 60 T. Both crystals show that Hc2(T)H_{c2}(T)'s along the c axis [Hc2c(T)H_{c2}^c(T)] and in an abab-planar direction [Hc2ab(T)H_{c2}^{ab}(T)] exhibit a linear and a sublinear increase, respectively, with decreasing temperature below the superconducting transition. Hc2(T)H_{c2}(T)'s in both directions deviate from the conventional one-gap Werthamer-Helfand-Hohenberg theoretical prediction at low temperatures. A two-gap nature and the paramagnetic pair-breaking effect are shown to be responsible for the temperature-dependent behavior of Hc2cH_{c2}^c and Hc2abH_{c2}^{ab}, respectively.Comment: 21 pages, 8 figure

    Real-Time Monitoring of Neural Differentiation of Human Mesenchymal Stem Cells by Electric Cell-Substrate Impedance Sensing

    Get PDF
    Stem cells are useful for cell replacement therapy. Stem cell differentiation must be monitored thoroughly and precisely prior to transplantation. In this study we evaluated the usefulness of electric cell-substrate impedance sensing (ECIS) for in vitro real-time monitoring of neural differentiation of human mesenchymal stem cells (hMSCs). We cultured hMSCs in neural differentiation media (NDM) for 6 days and examined the time-course of impedance changes with an ECIS array. We also monitored the expression of markers for neural differentiation, total cell count, and cell cycle profiles. Cellular expression of neuron and oligodendrocyte markers increased. The resistance value of cells cultured in NDM was automatically measured in real-time and found to increase much more slowly over time compared to cells cultured in non-differentiation media. The relatively slow resistance changes observed in differentiating MSCs were determined to be due to their lower growth capacity achieved by induction of cell cycle arrest in G0/G1. Overall results suggest that the relatively slow change in resistance values measured by ECIS method can be used as a parameter for slowly growing neural-differentiating cells. However, to enhance the competence of ECIS for in vitro real-time monitoring of neural differentiation of MSCs, more elaborate studies are needed
    corecore