Investigation of Stability and Power Consumption of an AlGaN/GaN Heterostructure Hydrogen Gas Sensor Using Different Bias Conditions

A Pd-functionalized hydrogen gas sensor was fabricated on an AlGaN/GaN-on-Si heterostructure platform. The AlGaN layer under the Pd catalyst area was partially recessed by plasma etching, which resulted in a low standby current level enhancing the sensor response. Sensor stability and power consumption depending on operation conditions were carefully investigated using two different bias modes: constant voltage bias mode and constant current bias mode. From the stability point of view, high voltage operation is better than low voltage operation for the constant voltage mode of operation, whereas low current operation is preferred over high current operation for the constant current mode of operation. That is, stable operation with lower standby power consumption can be achieved with the constant current bias operation. The fabricated AlGaN/GaN-on-Si hydrogen sensor exhibited excellent sensing characteristics; a response of 120% with a response time of < 0.4 s at a bias current density of 1 mA/mm at 200 °C. The standby power consumption was only 0.54 W/cm2 for a sensing catalyst area of 100 × 24 μm2

Bioactive Porous Particles as Biological and Physical Stimuli for Bone Regeneration

Even though bony defects can be recovered to their original condition with full functionality, critical-sized bone injuries continue to be a challenge in clinical fields due to deficiencies in the scaffolding matrix and growth factors at the injury region. In this study, we prepared bone morphogenetic protein-2 (BMP-2)-loaded porous particles as a bioactive bone graft for accelerated bone regeneration. The porous particles with unique leaf-stacked morphology (LSS particles) were fabricated by a simple cooling procedure of hot polycaprolactone (PCL) solution. The unique leaf-stacked structure in the LSS particles provided a large surface area and complex release path for the sufficient immobilization of BMP-2 and sustained release of BMP-2 for 26 days. The LSS was also recognized as a topographical cue for cell adhesion and differentiation. In in vitro cell culture and in vivo animal study using a canine mandible defect model, BMP-2-immobilized LSS particles provided a favorable environment for osteogenic differentiation of stem cells and bone regeneration. In vitro study suggests a dual stimulus of bone mineral-like (leaf-stacked) structure (a physical cue) and continuously supplied BMP-2 (a biological cue) to be the cause of this improved healing outcome. Thus, LSS particles containing BMP-2 can be a promising bioactive grafting material for effective new bone formation