Topological superfluidity with repulsive alkaline-earth atoms in optical lattices

Topological superfluids are of technological relevance since they are believed to host Majorana bound states, a powerful resource for quantum computation and memory. Here we propose to realize topological superfluidity with fermionic atoms in an optical lattice. We consider a situation where atoms in two internal states experience different lattice potentials: one species is localized and the other itinerant, and show how quantum fluctuations of the localized fermions give rise to an attraction and strong spin-orbit coupling in the itinerant band. At low temperature, these effects stabilize a topological superfluid of mobile atoms even if their bare interactions are repulsive. This emergent state can be engineered with ${}^{87}$Sr atoms in a superlattice with a dimerized unit cell. To probe its unique properties we describe protocols that use high spectral resolution and controllability of the Sr clock transition, such as momentum-resolved spectroscopy and supercurrent response to a synthetic (laser-induced) magnetic field

Additional file 1 of N-terminal pro-B-type natriuretic peptide is associated with clinical outcomes after transcatheter aortic valve replacement

Supplementary Material

RDI (DAF<0.1) under variable size intervals and GC-contents.

<p>RDI (DAF<0.1) under variable size intervals and GC-contents.</p

Median GC contents in variable intron size intervals and regions.

<p>*We pooled both 5′-exon and 3′-exon data as flanking exon data and compared them with intron data. The <i>P</i> values were calculated based on Wilcoxon rank sum test.</p

Estimation of key parameters.

<p>The distributions of derived allele frequency or DAF (A) and GC content (B) of minimal introns among the three studied populations: Africans (YRI), Europeans (CEU), and Asians (JPTCHB). The dashed lines divide the thresholds for DAF (A) and intron GC content (B).</p

Development of a Modified Process for the Kilogram-Scale Synthesis of c‑Met/ALK Inhibitor HS-10168

A modified synthetic route to c-Met/ALK inhibitor HS-10168 has been developed on a kilogram scale. The key steps of the new process include a Suzuki coupling reaction of nitro-containing bromopyridine <b>6</b> and <i>para</i>-phenol boronate <b>9</b> to give intermediate <b>10</b>, which was then converted to its triflate <b>11</b>. The phosphorus group was introduced by coupling of <b>11</b> and dimethylphoshine oxide <b>8</b> to give compound <b>12</b>, which was reduced to produce HS-10168

RDI (DAF<0.1) in different intron size intervals from combined datasets of the three populations.

<p>RDI (DAF<0.1) in different intron size intervals from combined datasets of the three populations.</p

Examples of Web servers and software packages developed and maintained in China.

<p>Examples of Web servers and software packages developed and maintained in China.</p

Relationship between GC content and intron size.

<p>GC contents in three size intervals from the three populations (DAF <0.1): YRI (A), CEU (B), and JPTCHB (C) as well as the combined data (all introns; D). The horizontal lines in the boxplots indicate the upper, the median, and the lower quartiles (from the top to the bottom).</p

The number and percentage of bioinformatics publications from China and in all of PubMed in the past decade.

<p>(A) The number of bioinformatics and computational biology publications from China in PubMed, retrieved from NCBI by the Entrez query “China[affiliation] AND (bioinformatics OR computational biology)”. MESH has a heading “Computational Biology” of which “Bioinformatics” is an Entry Term. The numbers provide a rough indication of growth of the field. They tend to be underestimated because some bioinformatics publications cannot be retrieved by keywords “bioinformatics OR computational biology”. However adding more keywords would increase the false positive rate significantly. (B) The number of all publications from China in PubMed, retrieved from NCBI by the Entrez query “China[affiliation]”. (C) The percentage of bioinformatics publications in China among all publications in China, in PubMed. (D) The number of bioinformatics and computational biology publications in all of PubMed, retrieved from NCBI by the Entrez query “bioinformatics OR computational biology”. (E) The number of all publications in PubMed. (F) The percentage of bioinformatics publications among all publications, in PubMed.</p