Correlations between visual acuity, HOAs, and posterior color grades.

<p>Correlations between visual acuity, HOAs, and posterior color grades.</p

Comparison of BSCVA between DMEK and DSAEK.

<p>A statistically significant improvement in BSCVA is obtained in each group (<i>P</i> < 0.001, Wilcoxon rank sum test). There is also a statistically significant difference in BSCVA between the two groups at all postoperative examinations (*<i>P</i> = 0.020, **<i>P</i> < 0.001, and **<i>P</i> < 0.001 at 1, 3, and 6 months, respectively; Mann–Whitney <i>U</i> test). Abbreviations: BSCVA, best spectacle-corrected visual acuity; DMEK, Descemet’s endothelial membrane keratoplasty; DSAEK, Descemet’s stripping automated endothelial keratoplasty.</p

Corneal aberrations in the central 6.0-mm zones in descemet membrane endothelial keratoplasty, descemet’s stripping automated endothelial keratoplasty, and control groups.

<p>Corneal aberrations in the central 6.0-mm zones in descemet membrane endothelial keratoplasty, descemet’s stripping automated endothelial keratoplasty, and control groups.</p

A patient with poor visual acuity and high posterior color grade 3 months after DMEK.

<p>(A) Slit-lamp photograph shows high transparency 3 months after DMEK. (B) Pachymetry after DMEK shows that the central corneal thickness is about 480 μm, which is considerably thinner than a healthy cornea. (C) Posterior map using AS-OCT after DMEK. Three months postoperatively, AS-OCT shows rapid improvement in corneal edema after DMEK. However, despite the clear cornea after DMEK, the visual acuity is 20/40. In this case, the posterior color grade is relatively high (grade 2). The figure demonstrates the characteristically irregular topography and increased irregular astigmatism at the posterior corneal surface in eyes with relatively poor visual acuity after DMEK. Abbreviations: AS-OCT, anterior segment optical coherence tomography; DMEK, Descemet’s endothelial membrane keratoplasty.</p

Representative cases of slit-lamp microscopy and AS-OCT after endothelial keratoplasty.

<p>(A) Slit-lamp photograph 6 months after DMEK. (B) Slit-lamp photograph 6 months after DSAEK. (C) AS-OCT section 6 months after DMEK. (D) AS-OCT section 6 months after DSAEK. (E) Posterior map using AS-OCT 6 months after DMEK. (F) Posterior map using AS-OCT 6 months after DSAEK. Postoperatively, a DMEK eye is difficult to distinguish from a normal eye after cataract surgery (A). However, we can see the scarring edge of the DSAEK graft (B). An AS-OCT section shows the natural posterior curvature in the DMEK eye (C), whereas the DSAEK eye has a meniscus-shaped posterior protrusion in the central cornea (D). The posterior color is cool in the DMEK eye (E), but red in the central cornea of the DSAEK eye (F). The arrows show the virtual peripheral edges of the DMEK and DSAEK grafts. Abbreviations: AS-OCT, anterior segment optical coherence tomography; DMEK, Descemet’s endothelial membrane keratoplasty; DSAEK, Descemet’s stripping automated endothelial keratoplasty.</p

Patient demographic and clinical characteristics before surgery.

<p>Patient demographic and clinical characteristics before surgery.</p

Correlation analysis between logMAR and clinical parameters.

<p>Correlation analysis between logMAR and clinical parameters.</p

The higher-order aberrations (HOAs) based on corneal opacity grading in corneal dystrophies.

<p>There were no significant differences in HOAs among corneal opacity grade 1, 2 and 3 in GCD2 (all Ps > 0.05). In the MCD group, the HOAs in eyes with corneal opacity grade 3 were significantly larger than those of grade 2 (P = 0.018). In the LCDI and LCDIIIA group, the HOAs in eyes with corneal opacity grade 2 were significantly larger than those of grade 1 (P = 0.022 and P = 0.017, respectively).</p

Patients’ demographics.

<p>Patients’ demographics.</p

Higher-order Aberration in Corneal Dystrophy.

<p>Higher-order Aberration in Corneal Dystrophy.</p