Effects of altitude and ibuprofen on the hypoxic ventilatory response (HVR = ΔV˙i / ΔSa_O2).

<p>Average HVR1 (± SD), which is the initial measure of the acute HVR, is plotted for 48 hrs of treatment with placebo (Pla, gray bars) or ibuprofen (Ibu, black bars) at sea level and high altitude. There was a significant effect of altitude (p = 0.001) and altitude by drug interaction (p = 0.03). Post hoc analysis showed all of the values were significantly different from each other (p < 0.05) except the two sea level values (p = 0.22).</p