Detailed mechanism for the reaction catalysed by <i>Tc</i>UGM.

<p>The mechanism includes the intermediates detected by experiments as well as those whose existence was inferred from theoretical considerations. Red color is used to denote the bonds being broken (solid line) or formed (dashed line), as well as the atoms involved. The distances between these atoms are labelled because they are used to define the reaction coordinates.</p

Main species of the reaction mechanism.

<p>Main species of the reaction mechanism.</p

values for key residues at every step of the reaction mechanism shown in Fig. 2.

<p> values for key residues at every step of the reaction mechanism shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109559#pone-0109559-g002" target="_blank">Fig. 2</a>.</p