Genome statistics.

<p>* Both ITR regions included, but missing the extreme termini.</p><p>** only one ITR region.</p

A. Amino acid alignment of mouse and rat 2′-5′ oligoadenylate synthetase with the putative squirrel poxvirus homolog.

<p>Coloured lines above the alignment indicates conserved functional regions and black lines indicates critical residues for function. Colours indicate different functional domains (Green, P-loop; Blue, PAFDAL; Yellow, LIRL; Peach, YALELLT and Pink, RPVILDPADP). The P-loop and PAFDAL domains hold the aspartic triad indicated by asterisks. The blue shading of the residues indicates the level of conservation, Dark blue is conserved in all species while light blue is conserved in just two. B. SQPV_0850 2′-5′ oligoadenylate synthetase – like molecule (blue) mapped to porcine 2′-5′ oligoadenylate synthetase OAS1 (PDB ID:1px5) (light yellow shadow); Green residues indicate the active DDD triad. Red residues indicate the equivalent residues RRE in the SQPV-OAS1 structure.</p

Comparison of the dsRNA interaction domain of SQPV_025, VACV_Cop E3L, human protein kinase R (PKR) and related proteins from other poxviruses.

<p>Conserved residues with the human form are indicated by a grey background. Asterisks above the alignment indicate those residues that have been shown to be necessary for dsRNA binding in E3L <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096439#pone.0096439-Chang1" target="_blank">[7]</a>.</p

Summary of sequenced poxvirus genomes with abbreviations.

<p>Summary of sequenced poxvirus genomes with abbreviations.</p

Characterisation of serotype Typhimurium isolates from wild birds in northern England from 2005 – 2006-3

<p><b>Copyright information:</b></p><p>Taken from "Characterisation of serotype Typhimurium isolates from wild birds in northern England from 2005 – 2006"</p><p>http://www.biomedcentral.com/1746-6148/4/4</p><p>BMC Veterinary Research 2008;4():4-4.</p><p>Published online 29 Jan 2008</p><p>PMCID:PMC2257933.</p><p></p>rised by serotyping, expressed as CFU/ml were determined on nutrient agar after the ability of the isolates to invade and persist in avian HD11 cells was assessed using a gentamicin protection assay. Within the sub-sample there were isolates of each phage type and . Typhimurium pulsed field group identified in this study (a – f) plus two control strains (F98 and SL1344)

Characterisation of serotype Typhimurium isolates from wild birds in northern England from 2005 – 2006-0

<p><b>Copyright information:</b></p><p>Taken from "Characterisation of serotype Typhimurium isolates from wild birds in northern England from 2005 – 2006"</p><p>http://www.biomedcentral.com/1746-6148/4/4</p><p>BMC Veterinary Research 2008;4():4-4.</p><p>Published online 29 Jan 2008</p><p>PMCID:PMC2257933.</p><p></p>reenfinch crop (Haematoxylin and Eosin stain): one central and one peripheral nodule of necrotic crop mucosa and submucosa with haemorrhage and surrounded by zones of infiltrating leucocytes. D: Greenfinch liver (Haematoxylin and Eosin stain): multifocal hepatic necrosis surrounded by a zone of macrophages and multinucleate giant cells which is further surrounded by lymphocytes

Characterisation of serotype Typhimurium isolates from wild birds in northern England from 2005 – 2006-1

<p><b>Copyright information:</b></p><p>Taken from "Characterisation of serotype Typhimurium isolates from wild birds in northern England from 2005 – 2006"</p><p>http://www.biomedcentral.com/1746-6148/4/4</p><p>BMC Veterinary Research 2008;4():4-4.</p><p>Published online 29 Jan 2008</p><p>PMCID:PMC2257933.</p><p></p>ained using and enzymes. Larger points represent sites from which more than one infected dead bird was found

Pulsed-field gel electrophoresis group and host origin of <i>Salmonella</i> Typhimurium isolates.

<p>Pulsed-field gel electrophoresis group and host origin of <i>Salmonella</i> Typhimurium isolates.</p

Distribution of <i>S.</i> Typhimurium DT40, DT56(v) and DT160 incidents, 1993–2012 in garden birds and humans.

<p>(a) Garden bird data expressed as total number of incidents by region (b) Human data expressed as number of incidents per 100,000 people by region, according to 2001 census data.</p

Number of garden bird incidents versus human incidents (per 100,000 people) with <i>S</i>. Typhimurium infection, 1993–2012.

<p>(a) Garden bird data expressed as total number of incidents by government office region (b) Human data expressed as number of incidents per 100,000 people by government office region, according to 2001 census data.</p