Additional file 2: of Intensified hand-hygiene campaign including soap-and-water wash may prevent acute infections in office workers, as shown by a recognized-exposure -adjusted analysis of a randomized trial

Sensitivíty analysis of predictive margins of weeks with reported symptoms of respiratory tract infections (RTI). (PDF 250 kb

The incidence of intussusception at three different periods.

<p>a) The crude and b) the smoothed incidence of intussusception per 100 000 person years during pre-vaccination years (1999–2005) with blue line, when vaccine was sold (2006–2009) with red line, and after the immunisation programme implementation (2010–2013) with green line by month of age for children less than 1 year in Finland. Fig is based on National Hospital Discharge Register data, and case verification has not been performed. Cases were referred to as 1 month of age from 15 days to 45 days of age, 2 months from 46 to 75 days of age etc.</p

Distribution of intussusception cases according to day of admission.

<p>Cases which have occurred after the first vaccine dose are marked green, after the second dose red and after the third dose blue. Vertical broken line separates the pre-specified risk and control intervals.</p

Composition of the national study cohort of culture-confirmed pulmonary tuberculosis cases treated at least 24 hours included in analysis

<p><b>Copyright information:</b></p><p>Taken from "Risk factors for poor tuberculosis treatment outcome in Finland: a cohort study"</p><p>http://www.biomedcentral.com/1471-2458/7/291</p><p>BMC Public Health 2007;7():291-291.</p><p>Published online 14 Oct 2007</p><p>PMCID:PMC2099439.</p><p></p

The Univariate and multivariate results for individual risk factors and the generalized additive model risk ratios with the spatial term of a waterborne outbreak in Vuorela, July 2012.

<p>The Univariate and multivariate results for individual risk factors and the generalized additive model risk ratios with the spatial term of a waterborne outbreak in Vuorela, July 2012.</p

Categorized distance and proportion of cases within those groups in a waterborne outbreak in Vuorela, July 2012.

<p>Categorized distance and proportion of cases within those groups in a waterborne outbreak in Vuorela, July 2012.</p

Epidemic curve of a waterborne outbreak in Vuorela, July 2012 based on the reported onset date of illness of the cases, and <i>E. coli</i> bacteria counts and chlorine levels in the point 7 (See Fig. 1) of the water distribution network.

<p>Epidemic curve of a waterborne outbreak in Vuorela, July 2012 based on the reported onset date of illness of the cases, and <i>E. coli</i> bacteria counts and chlorine levels in the point 7 (See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104713#pone-0104713-g001" target="_blank">Fig. 1</a>) of the water distribution network.</p

Microbiological results of faecal samples from symptomatic patients of a waterborne outbreak in Vuorela, July 2012.

<p>Methods used were cultivation¹, PCR/RT-PCR² (polymerase chain reaction/reverse transcripition-PCR), EM³ (electron microscopy) and/or EIA⁴ (Enzyme Immunoassay). ⁵<i>Campylobacter jejuni</i> and ⁶EHEC O157:H7 (from one sample) and ⁷sapovirus GII.P3 were isolated from the samples.</p

Phylogenetic relationships among OTUs (•) of the genus <i>Arcobacter</i> in a waterborne outbreak in Vuorela, July 2012.

<p>The tree was inferred from a maximum likelihood analysis of aligned 16S rRNA gene sequence (≈255 bp) and nodes with a bootstrap value ≥50% of 1 000 replicates are identified. <i>Sulfurospirillum deleyianum</i> (NR_074378) and <i>Campylobacter fetus</i> (L04314) were used as outgroup. Number in bracket represents the total amount of DNA/RNA reads identified in samples from A) the upper storage reservoir before cleaning, B) tap water during contamination and C) the upper storage reservoir after cleaning. *<i>A. butzleri</i>, <i>A. cryaerophilus</i> and <i>A. skirrowii</i> have been associated with gastrointestinal diseases <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104713#pone.0104713-Collado1" target="_blank">[76]</a>.</p