<i>B</i>. <i>bacilliformis</i> transmission routes.

<p>¹ Humans are the only known reservoir. ² Despite a report by Noguchi et al [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005863#ppat.1005863.ref006" target="_blank">6</a>], no confirmatory result has been published.</p

Multi-locus sequence typing (MLST) information of Oroya Fever samples.

<p>Multi-locus sequence typing (MLST) information of Oroya Fever samples.</p

Main facts on Carrion's disease.

<p>Main facts on Carrion's disease.</p

Phylogenetic tree of all the Sequence Types of <i>B</i>. <i>bacilliformis</i> as constructed an UPGMA cluster analysis with Bootstrap method.

<p>Phylogenetic tree of all the Sequence Types of <i>B</i>. <i>bacilliformis</i> as constructed an UPGMA cluster analysis with Bootstrap method.</p

Map of the geographical distribution of Carrion’s disease in Peru with the distribution of the SequenceTypes location.

<p>Map of the geographical distribution of Carrion’s disease in Peru with the distribution of the SequenceTypes location.</p

Dataset OROV

<p><b>First outbreak of Oropouche Fever reported in a non-endemic central-western region of the Peruvian Amazon. </b><b>Molecular diagnosis and clinical characteristics. </b></p><p><b>Introduction: </b>Oropouche virus (OROV) is an underreported and emerging infectious disease. Its incidence is underestimated mainly due to clinical similarities with other diseases that are also caused by arboviruses present in endemic areas. We report the first outbreak of OROV in the western region of the Peruvian Amazon in the department of Huanuco, Peru. </p><p><b>Methods</b>: This outbreak occurred in the region of Huanuco, Peru during July of 2016. Blood samples were taken from 268 patients who presented acute febrile syndrome to be later analyzed for Oropouche Virus via Polymerase Chain Reaction.</p><p><b>Results</b>: Of all 268 patients, 46 (17%) cases tested were positive for OROV. the most common symptom reported was headaches with a frequency of 87% (n=40) followed by myalgias with 76% (n=35), arthralgias with 65.2% (n=30), retro-ocular pain 60.8% (n=28) and hyporexia with 50% (n=23). </p><p> Concerning signs and symptoms that may suggest severe OROV infection, 4.3% (n=2) had low platelet count, 8.6% (n=4) had intense abdominal pain, and only 2.1% (n=1) had a presentation with thoracic pain<br></p

MOESM1 of Helicobacter pylori and its relationship with variations of gut microbiota in asymptomatic children between 6 and 12Â years

Additional file 1: Table S1. Nutritional status assessment in relation to the presence of H. pylori and the number of bacterial genre present in the intestinal microbiota

Dataset 2018

High prevalence of respiratory virus and atypical bacterium among children with a probable diagnosis of pertussis<div> <p> </p> <p>Jorge Valverde^1<b>†</b>, Stephanie Saiki^2<b>†</b>, Angela Cornejo-Tapia^1<b>*</b>, Fernando Vásquez-Achaya¹, Maria Esther Castillo³, Verónica Petrozzi-Helasvuo¹, Wilmer Silva-caso¹, Miguel Angel Aguilar-Luis^1,2,4, Olguita del Aguila⁵, Carlos Bada⁶, Erico Cieza-Mora⁷, Juana del Valle-Mendoza^1,2<b>*</b></p><div><br></div><div><p><b>Background: </b>Acute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries. Unfortunately, information regarding their epidemiology is still limited in Peru</p> <p><b>Methods:</b> A secondary data analysis was performed from a previous cross-sectional study conducted in children with a probable diagnosis of Pertussis from January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the following etiologies: Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus, Parainfluenza 1 virus, Parainfluenza 2 virus, Parainfluenza 3 virus, <i>Mycoplasma pneumoniae</i> and <i>Chlamydia pneumoniae</i>.</p> <p><b>Results:</b> A total of 288 patients were included. The most common pathogen isolated was Adenovirus (49%), followed by <i>Bordetella pertussis</i> (41%) from our previous investigation, the most prevelant microorganisms were <i>Mycoplasma pneumonia</i> (26%) and Influenza-B (19.8%). Coinfections were reported in 53.5% of samples and the most common association was found between <i>M. pneumoniae</i> and Adenovirus (9%). <b>Conclusions:</b> There was a high prevalence of Adenovirus, <i>Mycoplasma pneumoniae</i> and other etiologies in patients with a probable diagnosis of pertussis. Despite the presence of persistent cough lasting at least two weeks and other clinical characteristics highly suspicious of pertussis, secondary etiologies should be considered in children under 5 years-old in order to give a proper treatment.</p><br></div></div

Correlations of serum biomarker concentrations and IgM and IgG levels against <i>B</i>. <i>bacilliformis</i>.

<p>Only biomarkers with statistical significant associations with antibody levels are shown. P-values were computed through unadjusted linear regressions. The grey area shows the 95% confidence interval for predictions from the linear model.</p

Scatter matrix and Pearson coefficient of correlation for the clinical symptoms.

<p>Scatter matrix and Pearson coefficient of correlation for the clinical symptoms.</p