Baseline clinical variables associated with functional severity in AS patients.

<p>NS- no statistically significant.</p

SNPs associated with functional severity in AS patients.

§<p>- The p-values shown correspond to the allele frequencies test corrected by a single-value permutation test.</p><p>The symbols represent the results of the genotype frequencies association test before and after a logistic regression analysis using the age at disease onset and neck pain as covariates:</p>*<p>Significant genotype association (p<0.05) after logistic regression analysis with adjustment for age at disease onset and neck pain;</p>†<p>Borderline genotype association (0.05≥p<0.1) after logistic regression analysis with adjustment for age at disease onset and neck pain;</p>#<p>Significant genotype association (p<0.05) was lost after logistic regression analysis with adjustment for age at disease onset and neck pain.</p

Clinical characteristics related to disease severity with respect to the rs4819554 genotype distribution.

<p>Clinical characteristics related to disease severity with respect to the rs4819554 genotype distribution.</p

Clinical characteristics related to disease severity with respect to the rs4819554 genotype distribution.

<p>Clinical characteristics related to disease severity with respect to the rs4819554 genotype distribution.</p