Forest plot for rs11191416 in relation to SBP.

<p>The beta estimate and standard error are reported from the unconditional weighted analyses. P-values are reported from unconditional unweighted analyses.</p

Regional association plot for <i>PLEKHA7</i> in relation to DBP.

<p>Each circle represents a single variant. The triangle denotes the index variant. The color coding corresponds to the correlation (r²) between index variant and the other variants.</p

Forest plot for rs12806040 in relation to DBP.

<p>The beta estimate and standard error are reported from the unconditional weighted analyses. P-values are reported from unconditional unweighted analyses.</p

Characteristics of common variants identified across 6 blood pressure loci.

<p>Characteristics of common variants identified across 6 blood pressure loci.</p

Characteristics of the study participants.

<p>*PP calculated as SBP-DBP.</p>†<p>MAP calculated as (DBP+(SBP−DBP)/3).</p><p>All BP measures in the table are not adjusted for use of anti-hypertensive medication.</p><p>Characteristics of the study participants.</p

Summary of meta-analysis results for common variants associated with blood pressure traits with P-value&lt;0.001.

<p>The beta estimate and standard error are reported from meta-analysis of results from weighted analyses.</p><p>P-values are reported from meta-analysis unweighted analyses.</p><p>Direction of effect across contributing studies is shown for the unconditional analyses.</p><p>*MAF across all cohorts.</p><p>Summary of meta-analysis results for common variants associated with blood pressure traits with P-value&lt;0.001.</p

Assessment of variant enrichment in genes purportedly implicated in atrial fibrillation.

<p>Assessment of variant enrichment in genes purportedly implicated in atrial fibrillation.</p

Statistical power with current sample size and α = 5x10^-7.

<p>Statistical power with current sample size and α = 5x10^-7.</p

T1 test of association of rare variants with predicted functional impact on protein function or gene regulation in the 3 cohorts.

<p>Shown are the hazard ratios (HR) and associated confidence intervals for each cohort and the summary measure (diamond) from the meta-analysis.</p

Characteristics of variants in the <i>NINJ2</i> targeted region.

<p>Characteristics of variants in the <i>NINJ2</i> targeted region.</p