37,983 research outputs found
Morality Without Borders: A Vision of Humanity as Community
Identity politics is on the rise, and not only in America, but throughout the world. It is an inherent nationalism, and when unbridled and unchecked, unleashes an exclusive ethic into society appealing, not to an expansive moral ought, but one that is narrow and provincial, condemning and vilifying. The fact of national diversity and the imprint of dissimilar value orientations often cause fear and insecurity among groups and sub-groups who are apt to condense their value-orientation vis-à-vis their national or cultural identity, promoting ethical relativism and neglecting core human values. With a diminishing of religion’s consecrated and sanctified moral vision, many are falling upon an idealized version of national identity to set the parameters of their moral horizon. This is often expressed as a “moral superiority” implying the dominance of certain traditions and customs over those of others. We must be reminded that autocracy, national or religious, can be a tool of anyone seeking moral supremacy.
Looking back, history teaches that putting up constrictive, dogmatic borders is morally destructive, fencing out those with different views and stifling dialogue and civility within and without. Obviously, putting up ideological boundaries is apt to enclose those who profess a restrictive and/or superior ethic to unproductive and morality corrosive values. Being ethnocentric and tribal seems natural as there is a desire to protect our most cherished beliefs claiming moral superiority. Values are what define us; they are the substance of whom we are and reveal our commitments and convictions and their assumed authority. But our values can also limit our moral acuity, narrowing moral focus and diminishing its energy, unseeking of the commonalities that bind humanity to humanity. Clearly, it’s time to change this truncated narrative from an exclusive ethic to a morality without borders, exemplified as humanity as community.
Authoritarianism, displaying autocratic and anti-egalitarian values, is repressive and results in a limited and often amoral view of others. This we are witnessing today from all corners of the political spectrum, and not only in America, but elsewhere as well. For advancing a vision of the morally possible, an inclusive and expansive moral “ought” is needed, but terribly difficult to achieve or even articulate given the fact of cultural diversity, but we try. As Thomas Donaldson (1996, p.52) has noted, “We all learn ethics in the context of our particular cultures, and the power in the principles is deeply tied to the way in which they are expressed. Internationally accepted lists of moral principles, such as the United Nations’ Universal Declaration of Human Rights, draw on many cultural and religious traditions. As philosopher Michael Walzer (1983) has noted, ‘There is no 2 Esperanto (an artificial language devised in 1887 as an international medium of communication, based on roots from the chief European languages) of global ethics.’”
We simply express our view of a global ethic as a “moral human ecology” supportive of an unrestrained moral vision drawing both humanity and the environment into its definitive natural fiber. How often we write in abstractions and generalities forgetting the people about whom we talk. Their needs and the inhumanity heaped upon them are seldom noticed. There is some distance between us and others, but with empathy and care and an unrestrictive vision of others, this fissure can be closed. Differing customs and traditions require our reconsideration and respect. What we expose is an ethic of diversity-seeking those basic and common values grounded in the idea of “humanity” itself. Given the present-day discombobulation of value, especially moral value, as witnessed in present-day politics, nuclear proliferation, human exploitation and misery in Central America, and continuous war in both Africa and the Middle East, “morality without borders” presents a guiding metaphor beckoning our attention. “Humanity as Community” marks its location for it is a global imperative. Its possibilities are endless as it can become a beacon of hope in a divided world. But don’t expect miracles; this will be a slow and evolutionary process as we naturally hold our values close, seldom unleashing them for public scrutiny.
Philosophically, more than words are needed and more than well-crafted arguments are required for human rights, understood as moral rights, to be judiciously spread around the world. Commitment, respect, planning, and action are also required. For those who are leaders in human rights proliferation as well as ordinary people whose voices need to be heard, this is an enabling vision. It acknowledges the essence of humanity as moral and does not contradict what the religiously oriented call the “sacredness of human life.” It also acknowledges the principles foundational to human rights, such as fairness and justice, decency and responsibility, and the importance of human dignity, integrity, nurture, and care. Not mere generalities, these values are drawn from personal and collective experience and an unhampered propensity to care for others. To say they are innate (Haidt, 2012, p. 31) is perhaps an overreach, but to recognize their human importance is not. As ethicist Kurt Baier pointed out in 1971 (p. 810), morality looks at the world from the point of view of everyone, that “…to be moral…is to recognize that others too, have a right to a worthwhile life.
Benzonitrile as a Proxy for Benzene in the Cold ISM: Low-temperature Rate Coefficients for CN + C₆H₆
The low-temperature reaction between CN and benzene (C₆H₆) is of significant interest in the astrochemical community due to the recent detection of benzonitrile, the first aromatic molecule identified in the interstellar medium (ISM) using radio astronomy. Benzonitrile is suggested to be a low-temperature proxy for benzene, one of the simplest aromatic molecules, which may be a precursor to polycyclic aromatic hydrocarbons. In order to assess the robustness of benzonitrile as a proxy for benzene, low-temperature kinetics measurements are required to confirm whether the reaction remains rapid at the low gas temperatures found in cold dense clouds. Here, we study the C₆H₆ + CN reaction in the temperature range 15–295 K, using the well-established CRESU technique (a French acronym standing for Reaction Kinetics in Uniform Supersonic Flow) combined with pulsed-laser photolysis-laser-induced fluorescence. We obtain rate coefficients, k(T), in the range (3.6–5.4) × 10⁻¹⁰ cm³ s⁻¹ with no obvious temperature dependence between 15 and 295 K, confirming that the CN + C₆H₆ reaction remains rapid at temperatures relevant to the cold ISM
Magnons versus electrons in thermal spin transport through metallic interfaces
We develop a theory for spin transport in magnetic metals that treats the
contribution of magnons and electrons on equal footing. As an application we
consider thermally-driven spin injection across an interface between a magnetic
metal and a normal metal, i.e., the spin-dependent Seebeck effect. We show that
the ratio between magnonic and electronic contribution scales as
, with the Fermi temperature and the Curie
temperature . Since, typically, , the magnonic contribution
may dominate the thermal spin injection, even though the interface is more
transparent for electronic spin current.Comment: Contribution to the Special issue on Spincaloritronics in Journal of
Physics D: Applied Physic
APRIL:TACI axis is dispensable for the immune response to rabies vaccination.
There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings. To accomplish this goal, rabies virus (RABV)-based vaccines must rapidly activate B cells to secrete antibodies which neutralize pathogenic RABV before it enters the CNS. Increased understanding of how B cells effectively respond to RABV-based vaccines may improve efforts to simplify post-exposure prophylaxis (PEP) regimens. Several studies have successfully employed the TNF family cytokine a proliferation-inducing ligand (APRIL) as a vaccine adjuvant. APRIL binds to the receptors TACI and B cell maturation antigen (BCMA)-expressed by B cells in various stages of maturation-with high affinity. We discovered that RABV-infected primary murine B cells upregulate APRIL ex vivo. Cytokines present at the time of antigen exposure affect the outcome of vaccination by influencing T and B cell activation and GC formation. Therefore, we hypothesized that the presence of APRIL at the time of RABV-based vaccine antigen exposure would support the generation of protective antibodies against RABV glycoprotein (G). In an effort to improve the response to RABV vaccination, we constructed and characterized a live recombinant RABV-based vaccine vector which expresses murine APRIL (rRABV-APRIL). Immunogenicity testing in mice demonstrated that expressing APRIL from the RABV genome does not impact the primary antibody response against RABV G compared to RABV alone. In order to evaluate the necessity of APRIL for the response to rabies vaccination, we compared the responses of APRIL-deficient and wild-type mice to immunization with rRABV. APRIL deficiency does not affect the primary antibody response to vaccination. Furthermore, APRIL expression by the vaccine did not improve the generation of long-lived antibody-secreting plasma cells (PCs) as serum antibody levels were equivalent in response to rRABV-APRIL and the vector eight weeks after immunization. Moreover, APRIL is dispensable for the long-lived antibody-secreting PC response to rRABV vaccination as anti-RABV G IgG levels were similar in APRIL-deficient and wild-type mice six months after vaccination. Mice lacking the APRIL receptor TACI demonstrated primary anti-RABV G antibody responses similar to wild-type mice following immunization with the vaccine vector indicating that this response is independent of TACI-mediated signals. Collectively, our findings demonstrate that APRIL and associated TACI signaling is dispensable for the immune response to RABV-based vaccination
COLD-SAT: An orbital cryogenic hydrogen technology experiment
The COLD-SAT spacecraft will perform subcritical liquid hydrogen storage and transfer experiments under low-gravity conditions to provide engineering data for future space transportation missions. Consisting of an experiment module mated to a spacecraft bus, COLD-SAT will be placed in an initial 460 km circular orbit by an Atlas I commercial launch vehicle. After deployment, the three-axis-controlled spacecraft bus will provide electric power, experiment control and data management, communications, and attitude control along with propulsive acceleration levels ranging from 10(-6) to 10(-4)g. These accelerations are an important aspect of some of the experiments, as it is desired to know the effects that low gravity levels might have on the heat and mass transfer processes involved. The experiment module will contain the three liquid hydrogen tanks, valves, pressurization equipment, and instrumentation. At launch all the hydrogen will be in the largest tank, which has helium-purged MLI and is loaded and topped off by the hydrogen tanking system used for the Centaur upper stage of the Atlas. The two smaller tanks will be utilized in orbit for performing some of the experiments. The experiments are grouped into two classes on the basis of their priority, and include six regarded as enabling technology and nine regarded as enhancing technology
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