5,334 research outputs found
Modeling College Major Choices Using Elicited Measures of Expectations and Counterfactuals
The choice of a college major plays a critical role in determining the future earnings of college graduates. Students make their college major decisions in part due to the future earnings streams associated with the different majors. We survey students about what their expected earnings would be both in the major they have chosen and in counterfactual majors. We also elicit students' subjective assessments of their abilities in chosen and counterfactual majors. We estimate a model of college major choice that incorporates these subjective expectations and assessments. We show that both expected earnings and students' abilities in the different majors are important determinants of student's choice of a college major. We also show that students' forecast errors with respect to expected earnings in different majors is potentially important, with our estimates suggesting that 7.5% of students would switch majors if they made no forecast errors.choice of college major, subjective expectations
Soundless Revolution: Comparative Analysis On How To Propel The Global Ubiquitous IT Business Market According To Changes In The World Information Technology Market Environment
National policy and paradigm in enterprise management are also changing from "make & sell" to "sense & respond." A country or enterprise that makes and sells with no particular plan should fail. Countries and enterprises should sense what consumers and market demand and should respond to it quickly. Only when countries and enterprises catch the latest information and process it for application, they can expect to succeed. In this research, the researcher analyzed the research and industry trend of leading enterprises and countries such as Japan, among the United States, the European Union (EU) and the Far East Asia. Also the researcher examined trend in policy and propulsion status of enterprises in the United States. Comparative analysis on how to propel Ubiquitous Business Market in advanced enterprises in EU and Japan can be done too
Rejoinder: Demystifying Double Robustness: A Comparison of Alternative Strategies for Estimating a Population Mean from Incomplete Data
Rejoinder to ``Demystifying Double Robustness: A Comparison of Alternative
Strategies for Estimating a Population Mean from Incomplete Data''
[arXiv:0804.2958]Comment: Published in at http://dx.doi.org/10.1214/07-STS227REJ the
Statistical Science (http://www.imstat.org/sts/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Layered Long Term Co-Culture of Hepatocytes and Endothelial Cells on a Transwell Membrane: Toward Engineering the Liver Sinusoid
This paper presents a novel liver model that mimics the liver sinusoid where most liver activities occur. A key aspect of our current liver model is a layered co-culture of primary rat hepatocytes (PRHs) and primary rat liver sinusoidal endothelial cells (LSECs) or bovine aortic endothelial cells (BAECs) on a transwell membrane. When a layered co-culture was attempted with a thin matrigel layer placed between hepatocytes and endothelial cells to mimic the Space of Disse, the cells did not form completely separated monolayers. However, when hepatocytes and endothelial cells were cultured on the opposite sides of a transwell membrane, PRHs co-cultured with LSECs or BAECs maintained their viability and normal morphology for 39 and 57 days, respectively. We assessed the presence of hepatocyte-specific differentiation markers to verify that PRHs remained differentiated in the long-term co-culture and analyzed hepatocyte function by monitoring urea synthesis. We also noted that the expression of cytochrome P-450 remained similar in the cocultured system from Day 13 to Day 48. Thus, our novel liver model system demonstrated that primary hepatocytes can be cultured for extended times and retain their hepatocyte-specific functions when layered with endothelial cells
Making can-do into must-do: the way forward to health and wealth?
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Analysis Of Global Trends In Building Ubiquitous Information Technology Market Environment
This study found that each country, in order to propel the Global Ubiquitous Information Technology (IT) Business Market, has initiated strategies that utilize its own strengths in the IT industry. Ubiquitous information technology is recognized as a new strategy to propel the information industry and to enhance country's competitive power in the global information economy. IT companies in leading IT countries including the United States, Japan, and several European countries engage in active investment and research through a cooperative system among the industry, universities, and the government. Transition to a ubiquitous society may be a quiet revolution, but the reaching effects of the transition will be tremendous. Countries and enterprises should sense what consumers and market demand and should respond to it quickly. Only when countries and enterprises catch the latest information and process it for application, they can expect to succeed
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Installation of internal electric fields by non-redox active cations in transition metal complexes.
Local electric fields contribute to the high selectivity and catalytic activity in enzyme active sites and confined reaction centers in zeolites by modifying the relative energy of transition states, intermediates and/or products. Proximal charged functionalities can generate equivalent internal electric fields in molecular systems but the magnitude of their effect and impact on electronic structure has been minimally explored. To generate quantitative insight into installing internal fields in synthetic systems, we report an experimental and computational study using transition metal (M1) Schiff base complexes functionalized with a crown ether unit containing a mono- or dicationic alkali or alkaline earth metal ion (M2). The synthesis and characterization of the complexes M1 = Ni(ii) and M2 = Na+ or Ba2+ are reported. The electronic absorption spectra and density functional theory (DFT) calculations establish that the cations generate a robust electric field at the metal, which stabilizes the Ni-based molecular orbitals without significantly changing their relative energies. The stabilization is also reflected in the experimental Ni(ii/i) reduction potentials, which are shifted 0.12 V and 0.34 V positive for M2 = Na+ and Ba2+, respectively, compared to a complex lacking a proximal cation. To compare with the cationic Ni complexes, we also synthesized a series of Ni(salen) complexes modified in the 5' position with electron-donating and -withdrawing functionalities (-CF3, -Cl, -H, -tBu, and -OCH3). Data from this series of compounds provides further evidence that the reduction potential shifts observed in the cationic complexes are not due to inductive ligand effects. DFT studies were also performed on the previously reported monocationic and dicatonic Fe(ii)(CH3CN) and Fe(iii)Cl analogues of this system to analyze the impact of an anionic chloride on the electrostatic potential and electronic structure of the Fe site
Liver Sinusoid on a Chip: Long-Term Layered Co-Culture of Primary Rat Hepatocytes and Endothelial Cells in Microfluidic Platforms
We describe the generation of microfluidic platforms for the co-culture of primary hepatocytes and endothelial cells; these platforms mimic the architecture of a liver sinusoid. This paper describes a progressional study of creating such a liver sinusoid on a chip system. Primary rat hepatocytes (PRHs) were co-cultured with primary or established endothelial cells in layers in single and dual microchannel configurations with or without continuous perfusion. Cell viability and maintenance of hepatocyte functions were monitored and compared for diverse experimental conditions. When primary rat hepatocytes were co-cultured with immortalized bovine aortic endothelial cells (BAECs) in a dual microchannel with continuous perfusion, hepatocytes maintained their normal morphology and continued to produce urea for at least 30 days. In order to demonstrate the utility of our microfluidic liver sinusoid platform, we also performed an analysis of viral replication for the hepatotropic hepatitis B virus (HBV). HBV replication, as measured by the presence of cell-secreted HBV DNA, was successfully detected. We believe that our liver model closely mimics the in vivo liver sinusoid and supports long-term primary liver cell culture. This liver model could be extended to diverse liver biology studies and liver-related disease research such as drug induced liver toxicology, cancer research, and analysis of pathological effects and replication strategies of various hepatotropic infectious agents
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