OPLS-DA score plot showing a partial separation between patients with bipolar disorder I (top panel), bipolar disorder II (middle panel) and healthy controls (lower panel).

<p>Each participant’s score is represented by a circle. The scores were t[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0115562#pone.0115562.ref001" target="_blank">1</a>] values on the component predictive of diagnostic group. The vast majority (97%) of the participants were within a ±2 standard deviation limit according to Hotelling’s T². Positive values represent better overall performance.</p

Performance of euthymic patients with bipolar disorder I (BD I), bipolar disorder II (BD II), and healthy controls (C) on a neuropsychological test battery.

<p>The neuropsychological measures are arranged according to the size of the OPLS-DA loadings. Results are expressed as means, 95% confidence intervals (CIs) and effect sizes (<i>η</i>²). Percentage was calculated of patients scoring ≤ the 1.25 s.d. of the control group.</p><p><i>Note.</i></p><p>^a Pålsson et al, 2012,</p><p>^b loading on predictive component,</p><p>^c Games Howell otherwise Scheffé.</p><p>Performance of euthymic patients with bipolar disorder I (BD I), bipolar disorder II (BD II), and healthy controls (C) on a neuropsychological test battery.</p

Summary of demographic and clinical characteristics in patients with bipolar disorder I (n = 64) and bipolar disorder II (n = 44).

<p>The controls (n = 86) were matched for age and sex (X% female). No differences were found regarding education level between the bipolar disorder groups and the control group.</p><p>^a data from 47–64 patients</p><p>^b data from 36–44 patients</p><p>Summary of demographic and clinical characteristics in patients with bipolar disorder I (n = 64) and bipolar disorder II (n = 44).</p