Visual recognition task in the ANT: N 115- P 150- N 200- P 250 and N700 complex (the mean from all thalamic contacts from all patients in bipolar montage during the recognition task).

<p>Arrows mark fast and slow ERP components N115, P150, N200, P250, and N700. The black curve indicates a new stimulus (new picture); red indicates a repeated stimulus during the recognition phase (old picture). On axis <i>x</i> is time (in s). The statistical significance to baseline is highlighted by black and red horizontal lines.</p

The main characteristics of patients with ANT and hippocampal electrodes.

<p>*F:female</p><p>**M:male</p><p>***DNET:Dysembryoplastic neuroepithelial tumor</p><p>****MQ:memory quotient</p><p>*****IQ: intelligence quotient</p><p>******ANT: anterior nuclei of the thalamus.</p><p>The main characteristics of patients with ANT and hippocampal electrodes.</p

P300-like potentials in the hippocampus and the thalamus (the mean from all hippocampal and thalamic contacts from all patients in bipolar montage during the encoding and the recognition task).

<p>The black curve indicates a new stimulus (new picture/word: NP/NW); red indicates a repeated stimulus during the recognition phase (old picture/word: OP, OW). The arrow shows the beginning of the P300-like potential (red for the repeated stimulus, black for the new one.) Axis <i>x</i> is time (in s); axis <i>y</i> is amplitude in μV. The statistical significance to baseline is highlighted by black and red horizontal lines. The significant difference between tasks in the hippocampus is highlighted by a black rectangle. Simultaneously the difference between tasks is drawn—DIFF.</p

P300-like potentials: latency of P300-like potentials recorded from all contacts from the hippocampus versus all contacts from the ANT, mean and standard deviation.

<p>OP/ OW: old picture/ word, NP/NW: new picture/word.</p><p>Statistical significance of differences between Hippocampus and ANT is in column Diff. Statistical significance of differences between the old and new pictures/words is in line of Diff NP vs. OP or Diff NW vs. OW. Significance of differences</p><p>P<0.001 ***</p><p>P<0.01 **</p><p>P<0.05 *</p><p>NS: non-significant.</p><p>P300-like potentials: latency of P300-like potentials recorded from all contacts from the hippocampus versus all contacts from the ANT, mean and standard deviation.</p

An example of spatial representation of post-stimulus interactions after targets between all investigated brain sites in one subject (No.7).

<p>Correlation results are arranged in the triangular matrices into groups according to brain structures (delimited by black lines)(D) and in graphic form of “glass brains” with linked pairs of investigated electrode contacts (A – Coronal, B – Sagittal, C – Axial). Matrix values and links are colored according to the percentage of duration of the increase (red) or decrease (blue) in cross-correlations within time window 250–750 ms after stimulation. Three selected frequency bands – δ (left panel), β (middle panel), and upper γ (right panel).</p

Timing of significant post-target cross-correlation increases across all subjects and areas.

<p>The duration was determined as the mean level of corresponding changes over contact pairs, and the occurrence was given as the center of changes.</p

Relative incidences of significant post-stimulus changes in inter-areal cross-correlations (A – monopolar; B – bipolar) and post-stimulus power changes (C – monopolar; D – bipolar) across all investigated subjects.

<p>Statistical significance of target/frequent differences is indicated by asterisks.</p

Matrices with significant correlation changes in three subjects; three frequency bands – δ (2–4 Hz), β (12–20 Hz), and upper γ (55–95 Hz), and two different stimuli – targets vs.frequents, for monopolar and bipolar montages.

<p>The correlation increase is highlighted in red, decrease in blue. Each colored line corresponds to changes in a contact pair in time (notice all pairs of investigated subject’s contacts are represented in individual matrices for each patient). Green vertical lines define interval 250–750 ms after stimuli.</p

Spatial distribution of couplings/decouplings across all investigated subjects, in the time window 250–750 ms after targets.

<p>Three orthogonal views of a transparent “glass brain”; links are colored according to the percentage of duration of the increase (red) or decrease (blue) in cross-correlations within time window 250–750 ms after stimulation. Three selected frequency bands – δ (left panel), β (middle panel), and upper γ (right panel).</p

Temporal characteristics of significant cross-correlation changes after targets for monopolar (A) and bipolar montages (B).

<p>Standard deviations are given in brackets.</p