PLS-DA plot of plasma metabolic profiles obtained for patients and controls with prediction for QCs.

<p>▵ - small AAA, ▴ – large AAA, □ – control, + - Quality control Panel A shows PLS-DA model (R² = 0.852, Q² = 0.369) for all samples and all variables in three groups under investigation (A, S, and C). Panel B shows prediction for QC samples by the model obtained.</p

Identification of acylcarnitines that were significantly differentiating plasma profiles of AAA patients from controls.

<p>A vs C - (+)/(−) means increased/decreased abundance in large aneurysm group in comparison to controls, S vs C - (+)/(−) means increased/decreased abundance in small aneurysm group in comparison to controls, A vs S - (+)/(−) means increased/decreased abundance in large aneurysm group in comparison to small aneurysm group.</p

Characteristics of study participants.

<p>COPD – chronic obstructive pulmonary disease.</p><p>ILT – intraluminal thrombus.</p

Identification of lysophospholipids that were significantly differentiating plasma profiles of AAA patients from controls.

<p>A vs C - (+)/(−) means increased/decreased abundance in large aneurysm group in comparison to controls, S vs C - (+)/(−) means increased/decreased abundance in small aneurysm group in comparison to controls, A vs S - (+)/(−) means increased/decreased abundance in large aneurysm group in comparison to small aneurysm group.</p

Identification of metabolites that were significantly differentiating plasma profiles of AAA patients from controls.

<p>A vs C - (+)/(−) means increased/decreased abundance in large aneurysm group in comparison to controls, S vs C - (+)/(−) means increased/decreased abundance in small aneurysm group in comparison to controls, A vs S - (+)/(−) means increased/decreased abundance in large aneurysm group in comparison to small aneurysm group. Identity of metabolites marked with asterix (*) was confirmed by analyzis of the standard.</p

PLS-DA plot of plasma metabolic profiles obtained for age matched aneurysm patients and controls.

<p>▵ - small AAA, ▴ – large AAA, + - predicted AAA samples not matching in age Panel A shows PLS-DA model (R² = 0.835, Q² = 0.335) for plasma samples obtained from patients and controls matching in age (n = 11). Panel B shows prediction for additional samples of patients (4 with large and 4 with small AAA). Sample marked by the circle was obtained from the patient with AAA size of 5.4 cm, and was assigned to large AAA group because the patient was operated on.</p