Baseline demographic and clinical data of the study participants.

<p>TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, MTC-score: <i>Mycobacterium tuberculosis</i> contact score, BCG: Bacillus Calmette-Guérin.</p>#<p>Categorical variables expressed as number of subjects (n) and percentage (%) compared to those evaluated with the characteristic studied. Quantitative variables expressed as mean and interquartile range (IQR).</p>a<p>In the 12 weeks prior to the study.</p>b<p>Risk of malnutrition was defined as a Z score for weight less than −1 SDs for age and gender; malnutrition was defined −2 SDs for age and gender.</p

Odds ratio and confidence interal of 95% for the Tuberculosis Skin Test positive results according to time of exposure (months) to index case.

<p>Odds ratio and confidence interal of 95% for the Tuberculosis Skin Test positive results according to time of exposure (months) to index case.</p

Multivariate logistic regression according to factors for positive QFT results stratified by TST results.

<p>TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, MTC-score: <i>Mycobacterium tuberculosis</i> contact score, BCG: Bacillus Calmette-Guérin.</p>a<p>logistic regression coefficient related to quantitative variable.</p>b<p>Linear odds ratio; exponential to the regression coefficient.</p

Bivariate analysis and Multivariate logistic regression for TST results and QFT results.

<p>TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, MTC-score: <i>Mycobacterium tuberculosis</i> contact score, BCG: Bacillus Calmette-Guérin.</p>#<p>Categorical variables expressed as percentage (%) and quantitative variables expressed as mean and interquartile range (IQR).</p>a<p>In the 12 weeks prior to the study.</p>b<p>Linear odds ratio.</p

Odds ratio and confidence interval of 95% for the Tuberculin Skin Test –TST− (blue) and QuantiFERON-TB Gold in-Tube –QFT− (red) positive results according to the intensity of exposure to index case by <i>Mycobacterium tuberculosis</i> contact score (MTC-score).

<p>The MTC-score is from 0 to 15 and is based on the assumption that the gradient of <i>Mtb</i> exposure is a composite function of the infectivity of the index case (0–4), the duration of exposure -hours per day- (0–4), the relationship to index case (0–4) and the type of exposure (0–3).</p

Comparison of the main variables according to TST and QFT results.

<p>IQR: interquartile range,</p><p>N₁: number of subjects, TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, MTC-score: <i>Mycobacterium tuberculosis</i> contact score, n: number of subjects with intestinal helminths;</p><p>N₂: number of subjects studied for helminths.</p

Comparison of the TST and QFT results.

<p>TST: Tuberculin Skin Test, QFT: QuantiFERON-TB Gold In-Tube, n: number of subjects.</p

Flow diagram of enrolment (QFT: QuantiFERON-TB Gold In-Tube).

<p>Flow diagram of enrolment (QFT: QuantiFERON-TB Gold In-Tube).</p

Correlation between gestational age and birth weight and graphical representation of the 10th and 90th percentiles for females (A) and males (B) based on Brazilian-specific growth curves.

<p>SGA: Small for gestational age (< 10th percentile); AGA: Appropriate for gestational age (10th-90th percentile); LGA: Large for gestational age (>90th percentile); LBW: Low birth weight (<2500 g); Premature newborn (< 37 weeks). The intra-uterine growth retardation (IUGR) was defined as the newborn SGA. No differences were found by gender to IUGR (p = 0.686), LBW (p = 0.406) and prematurity (p = 0.968).</p