Comparison of fixational saccade amplitude in viewing and non-viewing eye.

<p>Comparison of fixational saccade amplitude in viewing and non-viewing eye.</p

Bivariate contour ellipse analysis.

<p>Bivariate contour ellipse analysis.</p

Demographic and clinical features.

<p>Demographic and clinical features.</p

Frequency of microsaccades and fixational saccades.

<p>Frequency of microsaccades and fixational saccades.</p

Correlation of fixational saccade amplitude with peak drift velocity and eye position variance.

<p>Correlation of fixational saccade amplitude with peak drift velocity and eye position variance.</p

Abnormal Fixational Eye Movements in Amblyopia - Fig 2

<p>(A) Scatter plots of summary of the effects of severity of amblyopia on median amplitude of fixational saccades during fellow eye viewing condition (x-axis) and amblyopic eye viewing condition (y-axis). Each symbol depicts one subject whereas the symbol type represents severity of amblyopia. The dashed line is the equality line. (B, C) Summarizes the distribution of the fixational saccade amplitude during fellow eye viewing condition (B) and amblyopic eye viewing condition (C). A normalized number of events in a given bin is plotted along the y-axis while the x-axis represents the bins of fixational saccade amplitude of the viewing eye. The gray line illustrates the normalized frequency histogram of microsaccade amplitude in normal controls. The red, green and black lines represent mild, moderate and severe amblyopia subjects.</p

Characteristics of ocular drifts.

<p>Characteristics of ocular drifts.</p

Saccadic parameters in PD patients, PSP patients and healthy controls.

<p>Saccade rates, magnitudes, peak velocity-magnitude relationship slopes and vertical components (of saccade direction) are indicated. Bars represent the average value across subjects of each group and the error bars indicate the standard error of the mean. Asterisks show significance (p<0.05, t-test).</p

Characteristics of fixational saccades across subject groups.

<p>First row, saccadic peak velocity/magnitude relationships. Second row, saccadic duration/magnitude relationships. Third row, saccade magnitude distributions. Fourth row, polar histograms of saccade directions. Each graph shows the combined data for all subjects in each group.</p

Clinical features of all patients.

*<p>On clinical examination, most patients and age-matched controlled subjects showed mild limitation of upgaze and mild impairment of convergence and smooth pursuit. HYS: Hoehn-Yahr Scale for Parkinsons’ disease <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058535#pone.0058535-Hoehn1" target="_blank">[18]</a> **All PSP patients showed impaired smooth pursuit and vergence eye movements.</p