Baseline characteristics stratified by mortality at 30 days after ICU admission (n = 341).

<p>Baseline characteristics stratified by mortality at 30 days after ICU admission (n = 341).</p

Kaplan-Meier survival estimate by %FOtotal ≥ 10% or < 10% in the sepsis group (n = 201) and the non-sepsis group (n = 140).

<p>In the sepsis group, there was a significant difference in survival among patients with %FOtotal ≥ 10% or < 10% (<i>P</i> < 0.001). However, in the non-sepsis group, there was no difference in survival (<i>P</i> = 0.56). %FOtotal = percentage of total fluid overload from baseline body weight from 3 days before CRRT initiation to ICU discharge. ICU = intensive care unit.</p

Univariate analysis for 30-day mortality after ICU admission in all subjects (n = 341).

<p>Univariate analysis for 30-day mortality after ICU admission in all subjects (n = 341).</p

Kaplan-Meier survival estimates by fluid overload status (n = 341).

<p>There was a significant difference in survival among patients with %FOtotal ≥ 10% (n = 124) or < 10% (n = 217) (<i>P</i> < 0.001). %FOtotal = percentage of total fluid overload from baseline body weight from 3 days before CRRT initiation to ICU discharge. ICU = intensive care unit.</p

Kaplan-Meier survival estimate and 30-day mortality among the 4 groups categorized by %FOpreCRRT and %FOtotal.

<p>There was a significant difference in survival among the 4 groups (<i>P</i> < 0.001). 30-day mortality was the highest in Group 4, followed by Group 3, Group 2, and Group 1 (78.8% vs. 62.6% vs. 51.1% vs. 44.1%; <i>P</i> value for the linear trend < 0.001). Group 1: n = 170, %FOpreCRRT < 10% and %FOtotal < 10%; Group 2: n = 47, %FOpreCRRT ≥ 10% and %FOtotal < 10%; Group 3: n = 91, %FOpreCRRT < 10% and %FOtotal ≥ 10%; and Group 4: n = 33, %FOpreCRRT ≥ 10% and %FOtotal ≥ 10%. %FOpreCRRT = percentage of fluid overload from baseline body weight during 3 days prior to CRRT initiation. %FOtotal = percentage of total fluid overload from baseline body weight from 3 days before CRRT initiation to ICU discharge. ICU = intensive care unit.</p

Kaplan-Meier survival estimate %FOtotal ≥ 10% or < 10% in the high SOFA score group (≥ 13, n = 174) and in the low SOFA score group (< 13, n = 167).

<p>In the high SOFA score group, there was a significant difference in survival among patients with %FOtotal ≥ 10% or < 10% (<i>P</i> < 0.001). However, in the low SOFA score group, there was no difference in survival (<i>P</i> = 0.06). %FOtotal = percentage of total fluid overload from baseline body weight from 3 days before CRRT initiation to ICU discharge. ICU = intensive care unit.</p