Additional file 3: Table S3. of Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

Associations between IGF levels and median TDLU span among women with benign breast disease, overall and stratified by menopausal status. (DOC 48 kb

Additional file 5: Table S5. of Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

Associations of IGF levels and TDLU count among women with benign breast disease with mutual adjustment for IGFBP-3 and IGF-I, overall and stratified by menopausal status. (DOC 44 kb

Additional file 1: Table S1. of Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study

Definitions of breast cancer subtypes that have been applied in previous BCAC manuscripts. Table S2 Number of breast cancer patients with reproductive risk factor data in the 34 BCAC studies assessed in this study. Table S3 Number of breast cancer case patients with tumor marker data in the 34 BCAC studies assessed in this study. Table S4 Distribution of tumor characteristics according to breast cancer subtypes. Table S5 Association between parity (ever versus never) and BC subtypes for age overall and for specific ages (40, 50 and 60 years). Table S6 Frequency table showing parity by subtype and age group. Table S7 Associations between age at menarche, age at FFTP and breast cancer subtypes. The same analysis as in Table 4 is performed but here parity is considered a continuous variable. Table S8 Effect of parity (ever versus never) on BC subtype risk across all ages at BC diagnosis and corrected for BMI. Associations between age at menarche, age at FFTP and breast cancer subtype risk. (DOCX 60 kb

List of participating studies and number of Caucasian subjects included in at least one GxE analysis.

<p>List of participating studies and number of Caucasian subjects included in at least one GxE analysis.</p

Frequencies and ORs for the c.541C>T mutation among the different patient subgroups in the Helsinki, Tampere, Oulu, and Belarus series.

<p>Frequencies and ORs for the c.541C>T mutation among the different patient subgroups in the Helsinki, Tampere, Oulu, and Belarus series.</p