Cartilage restoration of patellofemoral lesions: a systematic review

Purpose This study aimed to systematically analyze the postoperative clinical, functional, and imaging outcomes, complications, reoperations, and failures following patellofemoral cartilage restoration surgery. Methods This review was conducted according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). PubMed, EMBASE, and Cochrane Library databases were searched up to August 31, 2018, to identify clinical studies that assessed surgical outcomes of patellofemoral cartilage restoration surgery. The Methodological Index for Non-Randomized Studies (MINORS) was used to assess study quality. Results Forty-two studies were included comprising 1,311 knees (mean age of 33.7 years and 56% males) and 1,309 patellofemoral defects (891 patella, 254 trochlear, 95 bipolar, and 69 multiple defects, including the patella or trochlea) at a mean follow-up of 59.2 months. Restoration techniques included autologous chondrocyte implantation (56%), particulated juvenile allograft cartilage (12%), autologous matrix-induced chondrogenesis (9%), osteochondral autologous transplantation (9%), and osteochondral allograft transplantation (7%). Significant improvement in at least one score was present in almost all studies and these surpassed the minimal clinically important difference threshold. There was a weighted 19%, 35%, and 6% rate of reported complications, reoperations, and failures, respectively. Concomitant patellofemoral surgery (51% of patients) mostly did not lead to statistically different postoperative outcomes. Conclusion Numerous patellofemoral restoration techniques result in significant functional improvement with a low rate of failure. No definitive conclusions could be made to determine the best surgical technique since comparative studies on this topic are rare, and treatment choice should be made according to specific patient and defect characteristics

Programa terapêutico para mulheres na menopausa: relato de experiência do profissional de educaçaõ física residente

O propósito deste estudo é destacar as experiências de um programa terapêutico para mulheres na menopausa. O programa faz parte do Projeto Território Paulo Freire e UNESC atendendo mulheres da cidade de Criciúma - SC. As ações propostas são elaboradas por uma equipe interdisciplinar, composta por professores, residente, bolsistas e voluntários dos cursos de Educação Física, Psicologia e Enfermagem. Consideramos que os relatos das participantes retratam os benefícios de participar de um programa de saúde e evidenciam a importância de os profissionais da atenção básica se preocuparem e desenvolverem ações multiprofissionais de promoção de saúde.Palavras-chave: Exercício Físico. Menopausa. Promoção de Saúde

Programa terapêutico para mulheres na menopausa: relato de experiência do profissional de educaçaõ física residente

O propósito deste estudo é destacar as experiências de um programa terapêutico para mulheres na menopausa. O programa faz parte do Projeto Território Paulo Freire e UNESC atendendo mulheres da cidade de Criciúma - SC. As ações propostas são elaboradas por uma equipe interdisciplinar, composta por professores, residente, bolsistas e voluntários dos cursos de Educação Física, Psicologia e Enfermagem. Consideramos que os relatos das participantes retratam os benefícios de participar de um programa de saúde e evidenciam a importância de os profissionais da atenção básica se preocuparem e desenvolverem ações multiprofissionais de promoção de saúde.Palavras-chave: Exercício Físico. Menopausa. Promoção de Saúde

Energy transition process and community engagement on geographic islands: the case of Culatra Island (Ria Formosa, Portugal)

Islands have the potential to be precursors in the transition to clean energy, by adopting new technologies and applying innovative solutions that can serve as showcases at an international level. This paper is a contribution towards understating the importance of community engagement on energy transition processes. It covers multiple aspects of a green transition process, including technical, environmental, social, and economic issues. Starting by a participatory diagnosis process, the community of a small island located in Portugal (Culatra Island, Algarve), was challenged to lead the transition process and define different pillars of energy transition. The process brought together local authorities, academia, citizens and companies. Using practical examples, it is shown how the community is succeeding in tailoring new technological solutions for a green transition, according with the specific needs of the island, as expressed by the islanders themselves, including batteries, electric vehicles, retrofitting of homes, or heat pumps, which, when combined, could lay the foundations for the creation of a Renewable Energy Community and leverage socioeconomic benefits.info:eu-repo/semantics/acceptedVersio

Is bony morphology and morphometry associated with degenerative full-thickness rotator cuff tears? A systematic review and meta-analysis

To scope the scientific literature and analyze the influence of bony risk factors for degenerative full-thickness primary rotator cuff tear. Purpose To scope the scientific literature and analyze the influence of bony risk factors for degenerative full-thickness primary rotator cuff tear. Methods A systematic review of databases PubMed, Scopus, EMBASE, and Cochrane Library was performed up to June 30, 2018. Meta-analysis was performed with mean difference (MD) or risk ratio for degenerative full-thickness rotator cuff injury, and when there were ≥3 studies for the considered potential risk factor. Methodologic quality was assessed using the Newcastle-Ottawa scale. Results We analyzed 34 studies comprising 5,916 shoulders (3,369 shoulders with rotator cuff tear and 2,546 controls) and identified 19 potential risk factors for degenerative full-thickness rotator cuff tears. There was moderate evidence that a higher critical shoulder angle (MD = 4.41, 95% confidence interval [CI] 3.43 to 5.39), higher acromion index (MD = 0.06, 95% CI 0.04 to 0.09), and lower lateral acromion angles (MD = −7.11, 95% CI −8.32 to −5.90) were associated with degenerative full-thickness rotator cuff tears compared with controls. Moderate evidence showed that a type III acromion significantly increases the risk for full-thickness degenerative rotator cuff tear (risk ratio = 2.26, 95% CI 1.38 to 3.70). Conclusion There is moderate evidence that larger critical shoulder angle, higher acromion index, lower lateral acromion angles, and a type III acromion are significantly associated with degenerative full-thickness rotator cuff tears. Other potential risk factors identified showed insufficient evidence. Level of Evidence Level IV, systematic review of level II to IV studies

Resumos em andamento - Exercício e Saúde

Resumos em andamento - Exercício e Saúd

Resumos em andamento - Educação Física

Resumos em andamento - Educação Físic

Resumos concluídos - Enfermagem

Resumos concluídos - Enfermage

Symbiotic relationship of pharmacogenetics and drugs of abuse

Pharmacogenetics/pharmacogenomics is the study of how genetic variation affects pharmacology, the use of drugs to treat disease. When drug responses are predicted in advance, it is easier to tailor medications to different diseases and individuals. Pharmacogenetics provides the tools required to identify genetic predictors of probable drug response, drug efficacy, and drug-induced adverse events—identifications that would ideally precede treatment decisions. Drug abuse and addiction genetic data have advanced the field of pharmacogenetics in general. Although major findings have emerged, pharmacotherapy remains hindered by issues such as adverse events, time lag to drug efficacy, and heterogeneity of the disorders being treated. The sequencing of the human genome and high-throughput technologies are enabling pharmacogenetics to have greater influence on treatment approaches. This review highlights key studies and identifies important genes in drug abuse pharmacogenetics that provide a basis for better diagnosis and treatment of drug abuse disorders