Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases

We define phosphovariants as genetic variations that change phosphorylation sites or their interacting kinases. Considering the essential role of phosphorylation in protein functions, it is highly likely that phosphovariants change protein functions and may constitute a proportion of the mechanisms by which genetic variations cause individual differences or diseases. We categorized phosphovariants into three subtypes and developed a system that predicts them. Our method can be used to screen important polymorphisms and help to identify the mechanisms of genetic diseases

Universal factorization property of certain polycyclic groups

AbstractLet H be a torsion-free strongly polycyclic (torsion-free virtually polycyclic, resp.) group. Let G be any group with maximal condition. We show that there exists a torsion-free strongly polycyclic (torsion-free virtually polycyclic, resp.) group G˜ and an epimorphism ε:G→G˜ such that for any homomorphism ϕ:G→H, it factors through G˜, i.e., there exists a homomorphism ϕ˜:G˜→H such that ϕ=ϕ˜∘ε. We show that this factorization property cannot be extended to any finitely generated group G. As an application of factorization, we give necessary and sufficient conditions for N(f,g)=R(f,g) to hold for maps f,g:X→Y between closed orientable n-manifolds where π1(X) has the maximal condition, Y is an infra-solvmanifold, N(f,g) and R(f,g) denote the Nielsen and Reidemeister coincidence numbers, respectively

Determination of Cutting Date and Interval on Native Grass Management of Agricultural Waterways in South Korea

Agricultural waterways provide a buffer zone between crop fields and adjacent rivers or streams. Waterways are important resource for agriculture water management, water quality and biodiversity conservation. The total linear distance of waterway in Korea is about 180,000 km, and about 40% are concrete and about 60% are grassed waterways. At present, the percentage of concrete waterways is increasing because of their water management efficiency. Some argue that continued expansion of concrete waterways is not sustainable because it leads to potential-degradation of the earth\u27s environment. This concern has led to renewed efforts to use grassed waterways as an alternative to concrete. In addition, grassed waterways enhance the environment-friendly image of agriculture that Korea farmers want to promote. The objective of this experiment was to determine the effect of cutting date and interval of native grasses for water management efficiency of agricultural waterway