Impacts of Heavy Rain and Typhoon on Allergic Disease

AbstractObjectivesAllergic disease may be increased by climate change. Recent reports have shown that typhoon and heavy rain increase allergic disease locally by concentration of airborne allergens of pollen, ozone, and fungus, which are causes of allergic disease. The objective of this study was to determine whether typhoon and heavy rain increase allergic disease in Korea.MethodsThis study included allergic disease patients of the area declared as a special disaster zone due to storms and heavy rains from 2003 to 2009. The study used information from the Korea Meteorological Administration, and from the National Health Insurance Service for allergic diseases (asthma, allergic rhinitis, and atopic dermatitis).ResultsDuring a storm period, the numbers of allergy rhinitis and atopic dermatitis outpatients increased [rate ratio (RR) = 1.191; range, 1.150–1.232] on the sixth lag day. However, the number of asthma outpatients decreased (RR = 0.900; range, 0.862–0.937) on the sixth lag day after a disaster period. During a storm period, the numbers of allergic rhinitis outpatients (RR = 1.075; range, 1.018–1.132) and atopy outpatients increased (RR = 1.134; range, 1.113–1.155) on the seventh lag day. However, the number of asthma outpatients decreased to RR value of 0.968 (range, 0.902–1.035) on the fifth lag day.ConclusionThis study suggests that typhoon and heavy rain increase allergic disease apart from asthma. More study is needed to explain the decrease in asthma

Metallic 1T Phase, 3d1 Electronic Configuration and Charge Density Wave Order in Molecular Beam Epitaxy Grown Monolayer Vanadium Ditelluride.

We present a combined experimental and theoretical study of monolayer vanadium ditelluride, VTe2, grown on highly oriented pyrolytic graphite by molecular-beam epitaxy. Using various in situ microscopic and spectroscopic techniques, including scanning tunneling microscopy/spectroscopy, synchrotron X-ray and angle-resolved photoemission, and X-ray absorption, together with theoretical analysis by density functional theory calculations, we demonstrate direct evidence of the metallic 1T phase and 3d1 electronic configuration in monolayer VTe2 that also features a (4 × 4) charge density wave order at low temperatures. In contrast to previous theoretical predictions, our element-specific characterization by X-ray magnetic circular dichroism rules out a ferromagnetic order intrinsic to the monolayer. Our findings provide essential knowledge necessary for understanding this interesting yet less explored metallic monolayer in the emerging family of van der Waals magnets

Correction to Metallic 1T Phase, 3d1 Electronic Configuration and Charge Density Wave Order in Molecular-Beam Epitaxy Grown Monolayer Vanadium Ditelluride.

It has been brought to our attention that a mistake exists in the author list. The author “Johnson Goh” in the original article should be “Kuan Eng Johnson Goh”. His primary corresponding email is [email protected]

Fetal inflammatory response is positively correlated with the progress of inflammation in chorionic plate

Introduction: No information exists about the relationship among the progress of inflammation in chorionic-plate, fetal inflammatory response (FIR), funisitis, amnionitis and early-onset neonatal sepsis (EONS) in patients with either preterm labor or preterm premature rupture of membranes (preterm-PROM). The objective of current study is to examine this issue. Methods: Study population included 247 singleton preterm gestations (21.6 weeks <= gestational age at delivery <= 36 weeks) who had either preterm-labor or preterm-PROM with acute placental inflammation. We examined the intensity of FIR, and the frequency of fetal inflammatory response syndrome (FIRS), funisitis, amnionitis and proven or suspected EONS according to the progress of inflammation in chorionic-plate. The intensity of FIR was measured with umbilical cord plasma (UCP)-CRP concentration (ng/ml) at birth, and FIRS was defined as an elevated UCP-CRP concentration (>= 200 ng/ml). The progress of inflammation in chorionic-plate was divided with a slight modification from previously reported-criteria as follows: stage-0, inflammation-free chorionicplate; stage-1, inflammation restricted to subchorionic fibrin (SCF); stage-2, inflammation in the connective tissue (CT) of chorionic-plate without chorionic vasculitis; stage-3, chorionic vasculitis. Results: 1) Stage-0, stage-1, stage-2 and stage-3 of inflammation in chorionic-plate were present in 36.8% (91/247), 29.6% (73/247), 25.5% (63/247), and 8.1% (20/247) of cases; 2) UCP-CRP concentration at birth was significantly and positively correlated with the progress of inflammation in chorionic-plate (Spearman's rank correlation test, P<.000001, gamma = 0.391 and Kruskal-Wallis test, P<.001); 3) Moreover, FIRS, funisitis, amnionitis, and EONS were significantly more frequent as a function of the progress of inflammation in chorionic-plate. Discussion: The intensity of FIR and the frequency of FIRS were positively correlated with the progress of inflammation in chorionic-plate in patients with either PTL or preterm-PROM. This suggests chorionic-plate may be an independent compartment for the analysis of inflammation.N

Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in "indicated`` than in "spontaneous`` preterm birth

Objectives: The onset of preterm labor has been proposed to have survival value and to be adaptive in nature. This hypothesis would predict that induced preterm birth may be associated with higher rates of complications than spontaneous preterm birth. The purpose of this study was to determine if there is a difference in the frequency of neonatal respiratory distress syndrome (RDS), the most common neonatal complication, according to the etiology of preterm birth (e. g., preterm labor [PTL], preterm PROM, or pregnancies which ended because of maternal-fetal indications). Study design: The relationship between the occurrence of RDS and the obstetrical circumstances leading to preterm birth was examined in 257 consecutive singleton preterm births (gestational age: 24-32 weeks). Cases with major congenital anomalies were excluded. The study population was divided into two groups according to the cause of preterm birth: 1) preterm birth due to PTL with intact membranes or preterm PROM (spontaneous preterm birth group); and 2) preterm birth due to maternal or fetal indications (indicated preterm birth group). Results: 1) RDS was diagnosed in 47% of cases; 2) RDS was more common in patients with indicated preterm birth than in those with spontaneous preterm birth group (58.1% vs. 38.4%, P = 0.002); 3) Patients with indicated preterm birth had a significantly higher mean gestational age at birth, but lower mean birth weight, lower rate of histological chorioamnionitis and higher rates of cesarean delivery, 5 min Apgar score of <7, and umbilical arterial blood pH of <7.15 than those with spontaneous preterm birth (P<0.05 for each); 4) Antenatal corticosteroids were used in 73.4% of cases with indicated preterm birth and in 76.9% of those with spontaneous preterm birth; 5) Multivariate analysis demonstrated that indicated preterm birth was associated with an increased risk of RDS after adjusting for confounding variables (OR = 2.29, 95% CI 1.22-4.29). Conclusions: 1) The rate of RDS is greater following "indicated`` rather than spontaneous preterm birth; 2) This observation supports the view that spontaneous preterm labor is adaptive in nature.Goldenberg RL, 2008, LANCET, V371, P75, DOI 10.1016/S0140-6736(08)60074-4Morken NH, 2007, PAEDIATR PERINAT EP, V21, P458Costa S, 2007, EUR J OBSTET GYN R B, V131, P154, DOI 10.1016/j.ejogrb.2006.05.006Ananth CV, 2006, J MATERN-FETAL NEO M, V19, P773, DOI 10.1080/14767050600965882ROBERTS D, 2006, COCHRANE DB SYST REV, V3, P4454, DOI DOI 10.1002/14651858.CD004454.PUB2Ananth CV, 2005, OBSTET GYNECOL, V105, P1084, DOI 10.1097/01.AOG.0000158124.96300.c7JOBE AH, 2005, J PERINATOL S2, V25, pS31Chang EY, 2004, AM J OBSTET GYNECOL, V191, P1414, DOI 10.1016/j.ajog.2004.06.097SHINWELL ES, 2004, ARCH DIS CHILD-FETAL, V89, pF145Elimian A, 2003, OBSTET GYNECOL, V102, P352, DOI 10.1016/S0029-7844(03)00485-XMoutquin JM, 2003, BJOG-INT J OBSTET GY, V110, P30, DOI 10.1016/S1470-0328(03)00021-1Moss TJM, 2002, AM J OBSTET GYNECOL, V187, P1059, DOI 10.1067/mob.2002.126296Kramer BW, 2002, AM J PHYSIOL-LUNG C, V283, pL452, DOI 10.1152/ajplung.00407.2001Kallapur SG, 2001, AM J PHYSIOL-LUNG C, V280, pL527Hacking D, 2001, ARCH DIS CHILD, V84, pF117Bry K, 2001, ACTA PAEDIATR, V90, P74Jobe AH, 2000, AM J RESP CRIT CARE, V162, P1656Shimoya K, 2000, HUM REPROD, V15, P2234Winn HN, 2000, J PERINAT MED, V28, P210Carvalho MA, 1997, INT J GYNECOL OBSTET, V58, P197Bry K, 1997, J CLIN INVEST, V99, P2992YOON BH, 1995, AM J OBSTET GYNECOL, V172, P960SHAH DM, 1995, J PERINATOL, V15, P264SCHIFF E, 1993, AM J OBSTET GYNECOL, V169, P1096SAVITZ DA, 1991, AM J OBSTET GYNECOL, V164, P467HJALMARSON O, 1981, ACTA PAEDIATR SCAND, V70, P773BUSTOS R, 1979, AM J OBSTET GYNECOL, V133, P899

Prenatal Diagnosis of Bilateral Pulmonary Agenesis: a Case Report

We report a case of bilateral pulmonary agenesis (BPA), which was suspected during a prenatal US examination and diagnosed by fetal magnetic resonance imaging (MRI). BPA is an extremely rare congenital anomaly and, although many fetal structural defects can be detected with a high degree of confidence after introducing high-resolution US, the prenatal diagnosis of BPA remains problematic. Other thoracic abnormalities, such as a congenital diaphragmatic hernia, congenital cystic adenomatoid malformation, and pulmonary sequestration, should be excluded from the list of possible diagnoses before coming to the conclusion of BPA, because BPA is absolutely incompatible with extrauterine life, and an accurate internal diagnosis can prevent a futile intervention from being performed.Lee EY, 2008, RADIOLOGY, V247, P632, DOI 10.1148/radiol.2473062124Moreno-Alvarez O, 2008, ULTRASOUND OBST GYN, V31, P164, DOI 10.1002/uog.5201Obenauer S, 2008, CLIN IMAG, V32, P48, DOI 10.1016/j.clinimag.2007.08.019Joshi S, 2007, EARLY HUM DEV, V83, P789, DOI 10.1016/j.earlhumdev.2007.09.007Jeanty C, 2007, ULTRASOUND OBST GYN, V29, P378, DOI 10.1002/uog.3958Nazir Z, 2006, J PEDIATR SURG, V41, P1165, DOI 10.1016/j.jpedsurg.2006.02.012Gabarre JA, 2005, J ULTRAS MED, V24, P865Levine D, 2003, RADIOLOGY, V228, P379, DOI 10.1148/radiol.2282020604Vettraino IM, 2003, J ULTRAS MED, V22, P723Yang JI, 2003, J CLIN ULTRASOUND, V31, P214, DOI 10.1002/jcu.10157Laudy JAM, 2000, ULTRASOUND OBST GYN, V16, P284Kalache KD, 1997, FETAL DIAGN THER, V12, P360ENGELLENNER W, 1989, PEDIATR PATHOL, V9, P725

Successful Vaginal Delivery of a Pregnant Woman with Cantrell's Pentalogy

Cantrell's Pentalogy is a rare condition that consists of defects involving the abdominal wall, lower sternum, anterior diaphragm, pericardium, and heart. In the literature to date, pregnant women with Cantrell's Pentalogy have not been discussed. We performed successful vaginal delivery of a 23-yr-old nulliparous, primigravid woman who had been diagnosed with this condition. Diagnosis was based on cardiac catheterization, angiography, and echocardiogram, and abdominopelvic CT. Vaginal delivery may be an option for women with Cantrell's Pentalogy and may be attempted with caution